Guest guest Posted January 20, 2004 Report Share Posted January 20, 2004 > Has anyone ever used a DMSA suppository? Lots of people have. I do not recommend them, especially flipping from oral to other end use of DMSA. > My doctor would like to try > this with my two kids at night. Tell him to experiment on his own kids, just give you oral stuff so your kid gets better. >He can adjust the amount they get > through the pharmacy. He says that it will bypass the gut and more > will get into their system through a suppository. Unlikely in the extreme. There is also the issue of whether there is any DMSA in the suppostiory. The pharmacy may put it in, but unless the suppository is absolutely anhydrous there won't be any in a few days. Water is surprisingly soluble in fats and oils. > He also said that I > wouldn't have to wake them up in the middle of the night if I used > the suppository. Nonsense. Doesn't matter which end it goes in, it still only lasts 4 hours. >Any thoughts would be helpful. The doctor sounds pretty dangerously out of control. > Also, I thought that you had to use DMSA when you used ALA to make > sure the mercury didn't just stay in the body. No, that isn't why you do it. ALA removes it from the body just fine. The DMSA keeps the mercury that the ALA removes from the brain from having a chance to sneak back in - which most does not but some does. >Thanks for any advice - > I am just trying to get answers so that I can begin chelation. > Sharla Wiatt Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 12, 2006 Report Share Posted April 12, 2006 > > Hi all, > > I was able to attend the DAN conference last weekend. A couple >speakers mentioned that TD-DMSA was not showing impressive metal >pulls and they had been seeing great things with IVs and >suppositories. The trouble is that the objective of these speakers seems to be to get impressive 'metal pulls' using urine testing that is unreliable. I think that a better objective would be to remove metals in a way that leads to improvement of symptoms. IVs and suppositories give too much drug too fast and lead to too much metals being stirred up and redistributed to areas where they can do harm and may be difficult to remove later. The release of drug from suppositories is erratic. Oral dosing is much more reliable. J My kids are on TD-DMSA and have not really pulled anything to speak of. We did see little improvements after the first round but I don't think they were sustained. Both my children have terrible gut/yeast problems. I am very interested in the suppositories because of recent elevated liver enzymes (one speaker mentioned suppositories bypassing the liver?). They also mentioned that it was considerably less expensive than the TDs. With the half life of DMSA, would the suppository have to be a timed release? How would dosing work? Thanks for any thoughts or feedback. > > > --------------------------------- > Talk is cheap. Use Messenger to make PC-to-Phone calls. Great rates starting at 1 & cent;/min. > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 12, 2006 Report Share Posted April 12, 2006 > > > > Hi all, > > > > I was able to attend the DAN conference last weekend. A couple > >speakers mentioned that TD-DMSA was not showing impressive metal > >pulls and they had been seeing great things with IVs and >suppositories. 1. IV's are inappropriate, very dangerous, do not help, and I frankly question the sanity of any physician who uses iv DMPS routinely given the inevitable string of problems such as those described at www.dmpsbackfire.com that happen with this therapy. 2. Physicians as a rule can't do mass balance calculations, which are presented in the appendix of my book Amalgam Illness ( www.noamalgam.com ) where you can see that much more metal is removed by proper oral chelation than by iv therapy. 3. EDTA (a common iv) is useless for mercury. This has been known for a very long time and is discussed in standard MAINSTREAM medical texts such as the 1975 edition of Goodman and Gilman's Pharmacological Basis of Therapeutics. > The trouble is that the objective of these speakers seems to be to get > impressive 'metal pulls' using urine testing that is unreliable. It appears you know more about medicine than they do! > I think that a better objective would be to remove metals in a way > that leads to improvement of symptoms. I hope you can convince some doctors to come around to your view here! > IVs and suppositories give too much drug too fast and lead to too much > metals being stirred up and redistributed to areas where they can do > harm and may be difficult to remove later. > > The release of drug from suppositories is erratic. Oral dosing is > much more reliable. > > J I don't actually know if suppository absorption is erratic, but since nobody is going to stuff suppositories up their kid's behind every 3-4 hours (or even every 8) all the problems of harmful, dangerous and inappropriate protocols come along with their use. > My kids are on TD-DMSA and have not really pulled anything to speak > of. We did see little improvements after the first round but I don't > think they were sustained. Try oral administration. > Both my children have terrible gut/yeast problems. Most parents on this list who used oral chelation also had this situation and figured out how to deal with it. A few just had to bull their way through it and found it was well worth doing. >I am very interested in the suppositories because of recent > elevated liver enzymes (one speaker mentioned suppositories bypassing > the liver?). Suppositories do not bypass the liver any more than oral chelators do. TD does. > They also mentioned that it was considerably less > expensive than the TDs. With the half life of DMSA, would the > suppository have to be a timed release? Time release doesn't work. You have to give time release DMSA every 4 hours anyway. > How would dosing work? Every 4 hours or not at all. > Thanks > for any thoughts or feedback. > > > > > > --------------------------------- > > Talk is cheap. Use Messenger to make PC-to-Phone calls. > Great rates starting at 1 & cent;/min. > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 12, 2006 Report Share Posted April 12, 2006 They did mention better clinical improvement also. One MD claimed a child in his practice recovered on three IVs (not DMSA). They claimed more gains with the suppositories as well as greater pulls. I certain am concerned about the redistribution, that is why I am asking all of you. Thanks. > > > > Hi all, > > > > I was able to attend the DAN conference last weekend. A couple > >speakers mentioned that TD-DMSA was not showing impressive metal > >pulls and they had been seeing great things with IVs and >suppositories. > > > The trouble is that the objective of these speakers seems to be to get > impressive 'metal pulls' using urine testing that is unreliable. > > I think that a better objective would be to remove metals in a way > that leads to improvement of symptoms. > > IVs and suppositories give too much drug too fast and lead to too much > metals being stirred up and redistributed to areas where they can do > harm and may be difficult to remove later. > > The release of drug from suppositories is erratic. Oral dosing is > much more reliable. > > J > > > > > > > > My kids are on TD-DMSA and have not really pulled anything to speak > of. We did see little improvements after the first round but I don't > think they were sustained. Both my children have terrible gut/yeast > problems. I am very interested in the suppositories because of recent > elevated liver enzymes (one speaker mentioned suppositories bypassing > the liver?). They also mentioned that it was considerably less > expensive than the TDs. With the half life of DMSA, would the > suppository have to be a timed release? How would dosing work? Thanks > for any thoughts or feedback. > > > > > > --------------------------------- > > Talk is cheap. Use Messenger to make PC-to-Phone calls. > Great rates starting at 1 & cent;/min. > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 12, 2006 Report Share Posted April 12, 2006 > > They did mention better clinical improvement also. One MD claimed a > child in his practice recovered on three IVs (not DMSA). They > claimed more gains with the suppositories as well as greater pulls. The questions I'd like to ask them are what about the rest of the patients -- did any of them repond very badly to the IVs? Did any not respond either way? How many patients have been treated using that particular protocol? A few great stories is not enough info. Nell Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 12, 2006 Report Share Posted April 12, 2006 > > > > > > Hi all, > > > > > > I was able to attend the DAN conference last weekend. A couple > > >speakers mentioned that TD-DMSA was not showing impressive metal > > >pulls and they had been seeing great things with IVs and > >suppositories. > > > > > > The trouble is that the objective of these speakers seems to be to > get > > impressive 'metal pulls' using urine testing that is unreliable. > > > > I think that a better objective would be to remove metals in a way > > that leads to improvement of symptoms. > > > > IVs and suppositories give too much drug too fast and lead to too > much > > metals being stirred up and redistributed to areas where they can > do > > harm and may be difficult to remove later. > > > > The release of drug from suppositories is erratic. Oral dosing is > > much more reliable. > > > > J > > > > > > > > > > > > > > > > My kids are on TD-DMSA and have not really pulled anything to > speak > > of. We did see little improvements after the first round but I > don't > > think they were sustained. Both my children have terrible > gut/yeast > > problems. I am very interested in the suppositories because of > recent > > elevated liver enzymes (one speaker mentioned suppositories > bypassing > > the liver?). They also mentioned that it was considerably less > > expensive than the TDs. With the half life of DMSA, would the > > suppository have to be a timed release? How would dosing work? > Thanks > > for any thoughts or feedback. > > > > > > > > > --------------------------------- > > > Talk is cheap. Use Messenger to make PC-to-Phone calls. > > Great rates starting at 1 & cent;/min. > > > > > > Quote Link to comment Share on other sites More sharing options...
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