Guest guest Posted December 29, 2003 Report Share Posted December 29, 2003 what qualifies a person to get ammune testing done? AUTISM Ten years ago one in 10,000 Five years ago one in 500 Today one in 150 SCARED YET? www.momsonamissionforautism.org http://www.mercola.com/2001/sep/15/vaccines.htm Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 27, 2006 Report Share Posted May 27, 2006 I saw an immunologist, who ordered these tests and has made no comments about them. Would like to get feedback from those in the know. Abnormal results: Immune Deficiency Profile VIII Absolute cd 4 helper 1777 range 359-1519 %CD4 Pos Lymph 65.8 range 30.8-58.5 CD4/CD8 Ratio 4.11 range .92-3.72 WBC 14.3 range 4-10.5 RDW 17.4 range 11.7-15.0 Neutrophils 77 range 40-74 Monocytes 3 range 4-13 Neutrophils Absolute 11 range 1.8-7.8 ABS.CD3 + CD25 + Lymphs 1343 range 79-535 % CD3+CD25+Lymphs 49.75 range 4.93-25.85 IGG Subclass 1 341 range 422-1292 Complement C4 serum 55 range 9-36 C Reactive protein Quant. 23.1 range 0-4.9 Tumor Necrosis Factor Alpha 11.3 range 0-8.1 Natural Killer Cell Function LU30 4 range 8-170. Herpes Virus 6 IGG 40 hi Normal results: Raji cell quantitative normal 9.4 range <15.1 ANA Direct 25 range negative <100 Immune Complex c1q binding normal <1.2 negative <4.4 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 28, 2006 Report Share Posted May 28, 2006 it looks like these tests show many of the markers that are abnormal in CFS. it looks like the DR you went to follows much of the immune research that has gone on for CFS. the only test i really know anything about is th IGG1 which is the major subclass of IGG immunoglobulins. if this level is low enough they may reccomend treatment with IVIG - intravenous Immunoglobulins from pooled donated IGG. you can google IGG subclass deficiency and get more info on this topic. some PWCs have reported some benefit from this treatment. if you don't mind me asking, who is the DR that ran these tests? thanks bill > > I saw an immunologist, who ordered these tests and has made no comments about > them. Would like to get feedback from those in the know. > > Abnormal results: > > Immune Deficiency Profile VIII > Absolute cd 4 helper 1777 range 359-1519 > %CD4 Pos Lymph 65.8 range 30.8-58.5 > CD4/CD8 Ratio 4.11 range .92-3.72 > WBC 14.3 range 4-10.5 > RDW 17.4 range 11.7-15.0 > Neutrophils 77 range 40-74 > Monocytes 3 range 4-13 > Neutrophils Absolute 11 range 1.8-7.8 > ABS.CD3 + CD25 + Lymphs 1343 range 79-535 > % CD3+CD25+Lymphs 49.75 range 4.93-25.85 > IGG Subclass 1 341 range 422-1292 > Complement C4 serum 55 range 9-36 > C Reactive protein Quant. 23.1 range 0-4.9 > Tumor Necrosis Factor Alpha 11.3 range 0-8.1 > Natural Killer Cell Function LU30 4 range 8-170. > Herpes Virus 6 IGG 40 hi > > Normal results: > > Raji cell quantitative normal 9.4 range <15.1 > ANA Direct 25 range negative <100 > > > Immune Complex c1q binding normal <1.2 negative <4.4 > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 29, 2006 Report Share Posted May 29, 2006 Hi, I'm not an immune expert but it seems clear that your body is fighting an active infection based on elevated WBC count and CRP or possibly an auto immune disorder given this and your elevated TNF. I would guess infection. Your HHV-6 antibodies although positive are barely there and it's highly doubtful you have an active HHV-6 infection. I believe my IgG is, or was, 640. It's sad that he had no comments because these results are an indicator for further testing, in my opinion. Not to trash Immunologists but their primary interest is AIDS. I'm guessing you're either feeling fluish and/or pain with a fever? If you haven't already done so, I would have a full viral panel done, all the herpes viruses, along with coxsackie, echo and hepatitis along with bacterial testing including Chlamydia, Mycoplasma and Lyme. I'd also test for RA and Lupus to start. That is if you haven't already done so. You may have something that is very treatable, you just have to (hopefully) find out what is causing all that inflammation in your body. Try your best to find the source with pathogen testing. How long have you been sick? Terry > > I saw an immunologist, who ordered these tests and has made no comments about > them. Would like to get feedback from those in the know. > > Abnormal results: > > Immune Deficiency Profile VIII > Absolute cd 4 helper 1777 range 359-1519 > %CD4 Pos Lymph 65.8 range 30.8-58.5 > CD4/CD8 Ratio 4.11 range .92-3.72 > WBC 14.3 range 4-10.5 > RDW 17.4 range 11.7-15.0 > Neutrophils 77 range 40-74 > Monocytes 3 range 4-13 > Neutrophils Absolute 11 range 1.8-7.8 > ABS.CD3 + CD25 + Lymphs 1343 range 79-535 > % CD3+CD25+Lymphs 49.75 range 4.93-25.85 > IGG Subclass 1 341 range 422-1292 > Complement C4 serum 55 range 9-36 > C Reactive protein Quant. 23.1 range 0-4.9 > Tumor Necrosis Factor Alpha 11.3 range 0-8.1 > Natural Killer Cell Function LU30 4 range 8-170. > Herpes Virus 6 IGG 40 hi > > Normal results: > > Raji cell quantitative normal 9.4 range <15.1 > ANA Direct 25 range negative <100 > > > Immune Complex c1q binding normal <1.2 negative <4.4 > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 29, 2006 Report Share Posted May 29, 2006 Hi Terry I am not experienced at all in IgG and HHV-6 testing, but I saw that the immune test posted below showed low IgG subclass 1, maybe, as somebody posted, that could indicate an IgG subclass 1 deficiency. My daughter has serum IgA deficiency. IgA is supposed to protect against infections at mucosal surfaces, but I think since serum IgA in my daughter`s case cannot increase, her tests for IgA to different bacteria cannot be trusted, as IgA is always low, no matter if there is a mucosal infection or not. So my question is - could the same apply to IgG testing for HHV-6 - so that if one has IgG defiency, then there will not be very high HHV-6 IgG? ne > > > > I saw an immunologist, who ordered these tests and has made no > comments about > > them. Would like to get feedback from those in the know. > > Abnormal results: > > Immune Deficiency Profile VIII > > Absolute cd 4 helper 1777 range 359-1519 > > %CD4 Pos Lymph 65.8 range 30.8-58.5 > > CD4/CD8 Ratio 4.11 range .92-3.72 > > WBC 14.3 range 4-10.5 > > RDW 17.4 range 11.7-15.0 > > Neutrophils 77 range 40-74 > > Monocytes 3 range 4-13 > > Neutrophils Absolute 11 range 1.8-7.8 > > ABS.CD3 + CD25 + Lymphs 1343 range 79-535 > > % CD3+CD25+Lymphs 49.75 range 4.93-25.85 > > IGG Subclass 1 341 range 422-1292 > > Complement C4 serum 55 range 9-36 > > C Reactive protein Quant. 23.1 range 0-4.9 > > Tumor Necrosis Factor Alpha 11.3 range 0-8.1 > > Natural Killer Cell Function LU30 4 range 8-170. > > Herpes Virus 6 IGG 40 hi Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 29, 2006 Report Share Posted May 29, 2006 I had tested positive Bartonella henselae PCR test came back positive (cat scratch fever). Luekacyte Alkaline Phosphotate (LAP) abnormal. Result 322 range 32-182 Previous Herpes virus 6 Human IgG Antib >=1:1280 normal is , 1:80 titer In a message dated 5/29/2006 2:39:30 PM Eastern Standard Time, robin_tani@... writes: If I were to guess without knowing anything other than the data provided here, I would say you have a bacterial infection of some sort. You have elevated Neutophils, WBC, CRP (inflamation marker), and TNF. These are significantly more associated with markers of a bacterial infection than a viral infection. The HHV-6 IGG of 1:40 seems rather unremarkable. It's usually understood that titlers > 1:160 signifies a new recent infection of a reactivation of the virus. In any case, antibody testing for herpes viruses can't for sure rule out active infections and apparently neither can PCR tests. But really, from the numbers here it really sounds more like a bacterial infection. Have you even taken any extended course of antibiotics ? did you ever respond well to them ? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 29, 2006 Report Share Posted May 29, 2006 If I were to guess without knowing anything other than the data provided here, I would say you have a bacterial infection of some sort. You have elevated Neutophils, WBC, CRP (inflamation marker), and TNF. These are significantly more associated with markers of a bacterial infection than a viral infection. The HHV-6 IGG of 1:40 seems rather unremarkable. It's usually understood that titlers > 1:160 signifies a new recent infection of a reactivation of the virus. In any case, antibody testing for herpes viruses can't for sure rule out active infections and apparently neither can PCR tests. But really, from the numbers here it really sounds more like a bacterial infection. Have you even taken any extended course of antibiotics ? did you ever respond well to them ? > > I saw an immunologist, who ordered these tests and has made no comments about > them. Would like to get feedback from those in the know. > > Abnormal results: > > Immune Deficiency Profile VIII > Absolute cd 4 helper 1777 range 359-1519 > %CD4 Pos Lymph 65.8 range 30.8-58.5 > CD4/CD8 Ratio 4.11 range .92-3.72 > WBC 14.3 range 4-10.5 > RDW 17.4 range 11.7-15.0 > Neutrophils 77 range 40-74 > Monocytes 3 range 4-13 > Neutrophils Absolute 11 range 1.8-7.8 > ABS.CD3 + CD25 + Lymphs 1343 range 79-535 > % CD3+CD25+Lymphs 49.75 range 4.93-25.85 > IGG Subclass 1 341 range 422-1292 > Complement C4 serum 55 range 9-36 > C Reactive protein Quant. 23.1 range 0-4.9 > Tumor Necrosis Factor Alpha 11.3 range 0-8.1 > Natural Killer Cell Function LU30 4 range 8-170. > Herpes Virus 6 IGG 40 hi > > Normal results: > > Raji cell quantitative normal 9.4 range <15.1 > ANA Direct 25 range negative <100 > > > Immune Complex c1q binding normal <1.2 negative <4.4 > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 29, 2006 Report Share Posted May 29, 2006 ne, Have you tried increasing the IgA with with glutamine??? I would use 3-5000 a day. Away from other protein. Janet in SanDiego s_fibaek <s_fibaek@...> wrote: Hi Terry I am not experienced at all in IgG and HHV-6 testing, but I saw that the immune test posted below showed low IgG subclass 1, maybe, as somebody posted, that could indicate an IgG subclass 1 deficiency. My daughter has serum IgA deficiency. IgA is supposed to protect against infections at mucosal surfaces, but I think since serum IgA in my daughter`s case cannot increase, her tests for IgA to different bacteria cannot be trusted, as IgA is always low, no matter if there is a mucosal infection or not. So my question is - could the same apply to IgG testing for HHV-6 - so that if one has IgG defiency, then there will not be very high HHV-6 IgG? ne > > > > I saw an immunologist, who ordered these tests and has made no > comments about > > them. Would like to get feedback from those in the know. > > Abnormal results: > > Immune Deficiency Profile VIII > > Absolute cd 4 helper 1777 range 359-1519 > > %CD4 Pos Lymph 65.8 range 30.8-58.5 > > CD4/CD8 Ratio 4.11 range .92-3.72 > > WBC 14.3 range 4-10.5 > > RDW 17.4 range 11.7-15.0 > > Neutrophils 77 range 40-74 > > Monocytes 3 range 4-13 > > Neutrophils Absolute 11 range 1.8-7.8 > > ABS.CD3 + CD25 + Lymphs 1343 range 79-535 > > % CD3+CD25+Lymphs 49.75 range 4.93-25.85 > > IGG Subclass 1 341 range 422-1292 > > Complement C4 serum 55 range 9-36 > > C Reactive protein Quant. 23.1 range 0-4.9 > > Tumor Necrosis Factor Alpha 11.3 range 0-8.1 > > Natural Killer Cell Function LU30 4 range 8-170. > > Herpes Virus 6 IGG 40 hi This list is intended for patients to share personal experiences with each other, not to give medical advice. If you are interested in any treatment discussed here, please consult your doctor. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 30, 2006 Report Share Posted May 30, 2006 In a message dated 5/30/2006 2:55:26 PM Eastern Standard Time, robin_tani@... writes: Well that explains it. So are you getting antibiotics for the Bartonella infection ?? Any improvements since ? I was for awhile, felt very sick, had lots of side effects, never felt any improvement.. The next PCR test was negative. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 30, 2006 Report Share Posted May 30, 2006 Well that explains it. So are you getting antibiotics for the Bartonella infection ?? Any improvements since ? > > I had tested positive > Bartonella henselae PCR test came back positive (cat scratch fever). > > Luekacyte Alkaline Phosphotate (LAP) abnormal. Result 322 range 32-182 > > Previous Herpes virus 6 Human IgG Antib >=1:1280 normal is , 1:80 titer > > In a message dated 5/29/2006 2:39:30 PM Eastern Standard Time, > robin_tani@... writes: > If I were to guess without knowing anything other than the data > provided here, I would say you have a bacterial infection of some > sort. You have elevated Neutophils, WBC, CRP (inflamation marker), > and TNF. These are significantly more associated with markers of a > bacterial infection than a viral infection. The HHV-6 IGG of 1:40 > seems rather unremarkable. It's usually understood that titlers > > 1:160 signifies a new recent infection of a reactivation of the virus. > In any case, antibody testing for herpes viruses can't for sure rule > out active infections and apparently neither can PCR tests. > > But really, from the numbers here it really sounds more like a > bacterial infection. Have you even taken any extended course of > antibiotics ? did you ever respond well to them ? > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 31, 2006 Report Share Posted May 31, 2006 In a message dated 5/31/2006 2:54:57 PM Eastern Standard Time, robin_tani@... writes: Sorry to hear you had such a bad reaction to the antibiotics. What antibiotics were you taking and for how long ? Zithromax at hi doses, don't recall the exact amount for about 3 weeks. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 31, 2006 Report Share Posted May 31, 2006 Sorry to hear you had such a bad reaction to the antibiotics. What antibiotics were you taking and for how long ? > > In a message dated 5/30/2006 2:55:26 PM Eastern Standard Time, > robin_tani@... writes: > Well that explains it. So are you getting antibiotics for the > Bartonella infection ?? Any improvements since ? > I was for awhile, felt very sick, had lots of side effects, never felt any > improvement.. The next PCR test was negative. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 1, 2006 Report Share Posted June 1, 2006 It sounds really odd. During the course of these antibiotics, you never felt any better ? Not even for a day ? > > In a message dated 5/31/2006 2:54:57 PM Eastern Standard Time, > robin_tani@... writes: > Sorry to hear you had such a bad reaction to the antibiotics. What > antibiotics were you taking and for how long ? > Zithromax at hi doses, don't recall the exact amount for about 3 weeks. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 9, 2008 Report Share Posted August 9, 2008 How the antibody levels look? BARBIE Immune testing Is there a place to see what tests should be performed and what " normal " #'s are. I just got a copy of Tristens lab work IgG: 699 IgA: 61 IgM: 65 IgG1:553 IgG2: 111 IgG3: 33 IgG4: 40 She then had her Pneumovax, w/ 12 serotypes Diptheria: .92 Influenza B: .20 Tetanus: .21 That's all that was tested. Should I ask for more to be done before she starts her immunoglobulin therapy? She did have another Pneumovax today, since her #'s were low. Thanks for the help! le Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 20, 2008 Report Share Posted September 20, 2008 Hello--I'm not a medical expert by far, but I don't think being on atbs will affect the IGG panel. Atbs can affect the results of cultures, but I don't think they will affect the IGG numbers. I would definitely ask the doc before going to the lab, to make sure he's aware! Good luck, mom to Mark 7 CVID > > > > > > > > > > > > Hi all, > > A friend of mine has orders to get her son's IgG, IgM and CH50 drawn. He is currently sick with a sinus infection. > Does being sick alter any of those labs? > If so, how long do you wait, after being sick and how long after being off antibiotics? > > Thanks, > > Best Regards, > Krystena s > Ambassador, United Mitochondrial Disease Foundation > http://www.umdf.org/site/c.dnJEKLNqFoG/b.3041929/ > Region 4 " Genetics Care Coordation " > phone:859-749-7366 > fax:859-499-3477 > > > > > > Quote Link to comment Share on other sites More sharing options...
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