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Re: to plus A TIP FOR ALL OUT THERE

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In a message dated 12/17/2003 9:59:17 PM Central Standard Time,

ptclub@... writes:

and tonight I am not sleeping but at least I

am " talking " to some people who listens and understands me.

Thank you for that…….. and good morning to all of you!

Exactly how I feel most nights, Tia!! Anyway, I wanted to say welcome to the

family, and by the way, I think you have GREAT english!!!

Love Lana

" 'Be who you are and say what you feel because those

who mind don't matter and those who matter don't mind.' "

Dr. Suess

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to plus " A TIP FOR ALL OUT THERE "

PS: Oh, , what is Fentenyal patch and what is oxycontin and

what do you mean when you say " save for my back " .

Fentenyal patch is a pain reliever patch or can be a lolly pop/sucker that

you suck on. Here's info from Medscape

Fentanyl citrate is a strong analgesic used preoperatively, during surgery,

in the immediate postoperative period for its analgesic action. Fentanyl

citrate also is used intrabuccally (transmucosally) in the management of

breakthrough cancer pain.In addition, the drug may be used to prevent or

relieve tachypnea and postoperative emergence delirium. Fentanyl citrate is

used parenterally to provide preoperative anxiolysis and sedation and as a

supplement to anesthesia. The drug may be especially useful preoperatively

before surgery of short duration or minor surgery in outpatients and in

diagnostic procedures or treatments that require the patient to be awake or

very lightly anesthetized. Fentanyl citrate may be used as a supplement to

general or regional anesthesia, including neuroleptanalgesia in which it is

often used in combination with droperidol. When attenuation of the response

to surgical stress is especially important, fentanyl citrate may be

administered with oxygen and a skeletal muscle relaxant to provide

anesthesia without the use of additional anesthetic agents.Fentanyl citrate

intrabuccal (transmucosal) lozenges (Actiq®) are used for the management of

breakthrough cancer pain in patients who are already being treated with, and

are tolerant of, opiates used for chronic cancer pain.Patients are

considered opiate tolerant if they have been receiving at least 60 mg of

morphine sulfate daily, 50 mcg of transdermal fentanyl per hour, or an

equianalgesic dosage of another opiate for at least 1 week. Because of the

risk of life-threatening respiratory depression (e.g., hypoventilation),

intrabuccal (transmucosal) lozenges of fentanyl citrate (Actiq®) are

contraindicated in the management of acute or postoperative pain.In

addition, intrabuccal (transmucosal) lozenges of fentanyl citrate (Actiq®)

should not be used in patients who are not opiate tolerant.The manufacturer

states that intrabuccal (transmucosal) lozenges of fentanyl citrate (Actiq®)

should be administered only under the supervision of qualified clinicians

who are experienced in the use of opiates for the management of cancer

pain.The efficacy of intrabuccal (transmucosal) lozenges of fentanyl citrate

(Actiq®) for the management of breakthrough cancer pain has been studied in

a double-blind, placebo-controlled, randomized study in cancer patients 18

years of age and older who were already receiving the equivalent dosage of

at least 60 mg of oral morphine sulfate daily or at least 50 mcg of

transdermal fentanyl per hour for the management of chronic cancer pain and

who experienced at least one occurrence of breakthrough pain daily.

Oxycontin

Conventional preparations of oxycodone are used orally for the management of

moderate to moderately severe pain,such as that associated with bursitis,

injuries, dislocations, simple fractures, and neuralgia. Conventional

preparations also are used in the treatment of postoperative,

postextractional, and postpartum pain. Extended-release preparations are

used orally for the management of moderate to severe pain when a continuous,

around-the-clock analgesic is needed for an extended period of time;uses

include the treatment of cancer pain and nonmalignant pain, such as back

pain, osteoarthritis-related pain, and pain during rehabilitation following

total knee arthroplasty. The manufacturer states that oxycodone

hydrochloride extended-release tablets are not indicated for preoperative

(preemptive) analgesia, or for the relief of pain in the immediate (initial

12-24 hours ) postoperative period in patients not already receiving the

drug or in those whose pain is mild or not expected to persist for an

extended period of time. Oxycodone extended-release tablets are indicated

for postoperative use only in patients receiving the drug prior to surgery

or if the postoperative pain is expected to be moderate to severe and to

persist for an extended period of time.The extended-release preparation is

not intended for use on an as-needed (''prn'') basis.Dosage and

Administration from AHFS DIT

Administration

Oxycodone is administered orally as the hydrochloride salt or as the

hydrochloride and terephthalate salts, most often in combination with

acetaminophen or aspirin.Oxycodone hydrochloride extended-release tablets

should be swallowed whole and should not be broken, chewed, or crushed since

such physical alteration of the tablets could result in rapid release of the

drug and absorption of a potentially toxic dose.The manufacturer states that

oxycodone hydrochloride extended-release tablets should not be administered

rectally because of increased bioavailability and peak plasma concentrations

compared with oral administration.(See Pharmacokinetics.) Although food does

not substantially affect the extent of oral absorption of oxycodone

extended-release tablets, patients whose dosage is initially titrated to the

160-mg tablets (currently not commercially available in the US) should be

cautioned about dietary intake to prevent increases in peak plasma

concentrations resulting from administration with high-fat meals. (See

Pharmacokinetics.)Patients should be advised that the matrix core of the

tablets does not completely dissolve and may be passed in the stool.

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