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Sounds like his PSC is almost as bad as it can get. The next step as

his liver failure worsens is for all those symptoms and signs to get

worse, unfortunately. The ascites will get worse. The bleeding from his

gums and any sores will get worse. The varices will get worse. The

swelling of his feet and ankles will get worse. About the only good

thing will be that his MELD goes up. A low animal protein diet might be

of some help reducing the risk of Hepatic Encephalopathy (confusion and

coma related to worsening hepatic failure). I'm glad 's being

evaluated for tx as it's obvious he's had PSC for quite a while. Best

of luck.

Aubrey, MD

PSC '81, UC '90, LTX '98, Recurrence '05

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