RECTAL ROCKET & CAPSAICEN THOUGHTS.

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HI all..

Yoy!! I just don't know how to condense, so fair warning this is long. LOL

I'm going to first add a clip from a newsletter called ''The Compounder" that I've been receiving for a long time by a compounding pharmacist by the name of Larry Frieders. Not that I've used him (Petes still my fav) but some of his newsletters are very interesting, others have points I totally disagree with. *smile* But he definitely seems like a guy that truly wants to help in whatever way he can.

Anyway this was the latest one and two items (one, the Rectal Rocket and the other 'Sinusbuster',) were mentioned (items they compound themselves and sell) that really perked my ears up as a possibility for some of us. *smile* I'll let you read it then I'll continue below with some thoughts and why I wrote to Larry.

HEMORRHOIDS - A REAL PAIN IN THE BEHIND

Larry Frieders, R.Ph.

The Rectal Rocket Heals Hemorrhoids in 3 Days or Less Our Rectal Rocket is a special suppository designed to heal hemorrhoids in 3 days or less. It is more comfortable to use and more effective than a traditional suppository because of its unique design.

It does not get lost in the rectum but stays comfortably in place for many hours to soothe and heal inflamed tissue.

It treats both internal and external hemorrhoids simultaneously, so messy creams are not required.

The Rectal Rocket remains in place because a special groove permits the passage of gas.

Overnight use is convenient and doesn't interrupt daily activities.

Available in immediate-release and sustained-release formulations.

How Does the Rectal Rocket Work?

It's the design. The Rectal Rocket has a contoured front end and a flared bottom, so it treats both internal and external hemorrhoids simultaneously. It treats internal hemorrhoids by remaining at the point of insertion; it does not lapse into the rectum. The flared bottom remains in continuous contact with the outer surface of the anus to treat external hemorrhoids. The Rectal Rocket always remains in place because a special groove permits the passage of gas. Why Use the Rectal Rocket?

Comfort, Effectiveness, and Convenience! Suppositories are not the most pleasant form of medication, but if you're dealing with hemorrhoids, you don't have many options. When compared with traditional suppositories, Rectal Rockets offer excellent absorption and superior comfort, and they usually heal both internal and external hemorrhoids with as few as 3 applications. They are used at bedtime, and they provide immediate relief from pain and itching.

Better Drug Absorption. The Rectal Rocket’s design allows it to remain in continuous contact with internal and external inflamed areas throughout absorption. Immediate or Extended Release. Formulations that allow the drug to be absorbed immediately or over several hours can be made.

Hemorrhoids Heal with Fewer Doses. Traditional suppositories can lapse into the rectum, and when they lose direct contact with inflamed tissue, both types of hemorrhoids remain untreated. The extended-release Rectal Rocket can dramatically bring about healing in as few as 3 doses.

Better Comfort = Better Compliance. No need to use a traditional suppository plus a cream! The Rectal Rocket offers prolonged relief in 1 dosage form for both types of hemorrhoids.

The basic formulation provides lidocaine (an anesthetic) and hydrocortisone (an anti-inflammatory) in a special suppository blend.

Find Out More. . .Your doctor can prescribe a customized Rectal Rocket formulation for you. We also have formulas for treating systemic pain and anal fissures. Doctors who want specifics about these preparations or more information about the many possible Rectal Rocket formulations may contact the pharmacists at The Compounder or Info@....

The Compounder also Recommends:

SINUSBUSTERS

So many of us are plagued by sinus problems - headaches, dripping, sneezing, allergies, colds, and so on. Over the years I've tried all sorts of remedies and I never found anything that worked as well as these various sprays.

They each contain capsaicin - the stuff that makes peppers HOT. It is in a very weak solution, but it still burns when you first use it. This exhilarating bite is not a burn -- the formulas are non-caustic and non-addictive. When you introduce the capsicum to the blood vessels in your nose, the feeling is quite powerful. In fact, it’s quite similar to the sensation felt when you catch a little whiff of black pepper up your nose while cooking or seasoning your food -- only a bit stronger. But, WOW, does it ever work. I use these formulas myself and I don't hesitate to recommend them. -

Larry

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Dee here again.

So.... I read that and I thought first about women who have vaginal LP (lichen Planus) and since they often have to use anal suppository steroids but in the vagina for the pain and to prevent adhesions, I thought this 'might' be a perfect product for them.

Then I thought about others with hemmorhoids or anal fissures so that was a natural 'fit', (no pun intended, LOL).... Plus those with LS, since it can go around the rectum as well as the vulva that perhaps that might work for them too, since both LSers and LPers use a strong steroid like Clobetasol. His suppository would be quite mild by comparison but would bring pain relief I'm thinking. (with hydrocortisone and lidocaine)

And secondly the other item I was thinking about was those who've used or might try the Capsaicen cream/ointment on the vulva (That is sometimes suggested by K. Spadt and others) and the science behind it with it blocking substance P makes good sense to me as I understand it, but usually it can be extremely irritating that many don't stay with it very long... so again I thought gosh this product doesn't sound nearly as potent plus being a spray it might work even better than what is typically used on the vulva.

Anyway I wrote Larry and explained our groups and various conditions in some detail as to the pain suffered etc.etc.,and about how both items just 'may' be something we could possibly use and wondered what he thought about it using it as I described the situation.

This was his reply:

Hello Dee;

Thanks for writing.

Regarding the Rectal Rockets for vaginal use... On first thought, I'd think the anatomical differences would reduce the usefulness in the vagina. However, it may be worth a try for a couple of reasons.

The base I use melts and can flow around the vaginal cavity - both inside and out. "Regular" suppositories usually release their medication directly. The melting feature of our base might allow the medication to be more evenly distributed. The flared end may keep the Rectal Rocket in contact with the outer part of the vagina more effectively than a "standard" suppository. The groove would not offer any advantage for this use - but it will be there nonetheless because it's part of the mold.

I can incorporate practically any medications into the Rectal Rocket.

(I loved that idea, Dee)

Of course, using the Rectal Rocket in the anal area could be VERY helpful for those women where the condition affects that area.

Again, the melting aspect can deliver medication over a larger area and the shape can help apply the medicine to both the internal and external space.

When the condition ONLY affects the exterior anal ring I can make the Rectal Rocket in two stages - the inner part being mostly inert and the outer part containing most of the medication.

(Comment by Dee...I really liked this idea and would be perfect for those with anal 'LS' since it doesn't go inside the rectum...(that part would not have the medication) PLUS even for the vagina since LS doesn't go inside there either, But LP may/does and why I thought of it for vaginal LP.)

The variations are extensive. Clobetasol (a steroid) is easy to incorporate into this formulation. The most common formula for hemorrhoids is a combination of hydrocortisone (similar to clobetasol but not as potent, a mild steroid) and lidocaine (an anesthetic).

I'm a compounder so I can include almost anything the doctor would want.

(secondly)

About Capsaicin, that is the active ingredient in hot peppers. The level of "burn" is directly related to the concentration of that chemical. A person would want to be very careful using capsaicin around the vaginal or rectal areas.

You have a creative mind Dee - considering a mild 'Sinusbuster' spray for vaginal use. It seems like something worth trying. Before fully agreeing I'd want to compare the strength in the spray with the concentrations that doctors have recommended.

If the Sinusbuster is still too strong I might be able to formulate something more acceptable - maybe even incorporating a dose (of the capsaicin) into the suppository base I use for Rectal Rockets. This is definitely worth considering. I'd be happy to work with doctors and patients to arrive at a solution that meets the need.

Regards

Larry J Frieders, RPh, MMgt, MAhttp://www.thecompounder.com/340 Marshall Ave Unit 100

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Me once again. *smile*

Anyway I thought I'd throw it out there as it made some sense to me and I trust the guy, though like I said I do not agree with some few of his ideas (mainly progesterone,*grin*) but doesn't mean he's not excellent with other things.

Plus the fact that steroids can be wonderful for V. skin pain relief and we really shouldn't be afraid of one (mild for most conditions and potent for LS or LP) but if it's used judiciously for any kind of skin conditions (once all pathogens have been ruled out) they really can work wonders used correctly and not abused or overused.

Plus he uses a very mild steroid AND it has the lidocaine in it. But no doubt he could make that combo up in a cream base as well, and the Rectal Rocket (LOL) sounds great for those who do have hemmoroids..

AND about the Capsaicen? I know we haven't discussed that in a long time on group...(by the way this is NOT for LS but for vulvodynia or vestibulitis etc.,) and it's still a treatment that is offered and his may be a little milder 'and a spray' as long as a doctor is willing to talk with him to make it to the patients needs.. it'd be worth a try I would think.

Anyway I got the biggest chuckle out of the 'Rectal Rocket' name, LOL and thought it great that he responded so quickly. So for what it's worth.

Always writing others and seeking help or ideas for us.*smile*

hugs to all, Dee~