Re: Can't get the lead out!!

[Guest guest]

In a message dated 29/6/03 5:43:44 am, dagmarjahr@... writes:

> My understanding is, that the DMSA takes the lead out of the blood and that

> the lead then leaks out of the bones back into the blood.

>

Could this actually happen? Wouldn't it mean the disintegration of bone?

would any body explain this to me? I'm not being sarcastic, am geniunely

wondering. Nicky has lead.

What about trying EDTA instead of DMSA? Would that make any difference?

marti

[Guest guest]

It is my understanding that it takes longer to get lead out because it is

stored in the bones and gradually " dumps " so it takes much longer to

chelate lead. Correct me if I am wrong or not explaining it quite right.

[ ] Can't get the lead out!!

> Hello -

>

> I have a ten year old that has been undergoing chelation on DMSA for

> a year and a half and still his test results show high lead. Anyone

> have a case this stubborn or have any suggestions?

>

> It's not that his lead hasn't reduced, but it's hover around the same

> number for the past 10 months. It's like he's re-accumulating lead,

> but I can't imagine from where.

>

> Thanks for any help,

> Sheri

>

>

>

> =======================================================

>

[Guest guest]

Hi Sheri,

How do you test for the lead? If you test urine, maybe it is to be expected,

that the lead level is fairly constant. My understanding is, that the DMSA takes

the lead out of the blood and that the lead then leaks out of the bones back

into the blood. The reduction of lead might therefore be mostly in the bones

where I expect you can't test. Maybe the reduction in the blood will be only

right at the end, when there is no lead left in the bones to leak into the

blood.

Dagmar.

[ ] Can't get the lead out!!

Hello -

I have a ten year old that has been undergoing chelation on DMSA for

a year and a half and still his test results show high lead. Anyone

have a case this stubborn or have any suggestions?

It's not that his lead hasn't reduced, but it's hover around the same

number for the past 10 months. It's like he's re-accumulating lead,

but I can't imagine from where.

Thanks for any help,

Sheri

[Guest guest]

Hi Marti,

I expect the lead in the bones would be replaced by calcium again. I am no

expert, but this is my understanding.

Dagmar.

Re: [ ] Can't get the lead out!!

In a message dated 29/6/03 5:43:44 am, dagmarjahr@... writes:

> My understanding is, that the DMSA takes the lead out of the blood and that

> the lead then leaks out of the bones back into the blood.

>

Could this actually happen? Wouldn't it mean the disintegration of bone?

would any body explain this to me? I'm not being sarcastic, am geniunely

wondering. Nicky has lead.

What about trying EDTA instead of DMSA? Would that make any difference?

marti

[Guest guest]

> Hello -

>

> I have a ten year old that has been undergoing chelation on DMSA for

> a year and a half and still his test results show high lead. Anyone

> have a case this stubborn or have any suggestions?

I would suggest that you keep chelating.

Also, if you did not initially look for lead exposure sources,

I would also suggest doing that.

>

> It's not that his lead hasn't reduced, but it's hover around the same

> number for the past 10 months. It's like he's re-accumulating lead,

> but I can't imagine from where.

I concur with the comments others have made about lead taking a long

time to remove from the body. This is normal. It takes a couple

of years?

Moria

[Guest guest]

Sheri,

What media are they testing? Blood, urine, hair?

>

You've tested water at home and school (some still use lead pipes and school

water fountains are often a source)? soil around the house (from paint chips or

fallout from leaded gasoline use)? Paint at home and in the school?

>

Also, if he's on a calcium suplement you need to know the source since dolomite

(cow bones) and oyster shell are both known to contain lead.

>

Lead does take a long time to chelate.

S

I have a ten year old that has been undergoing chelation on DMSA for <BR>

a year and a half and still his test results show high lead.  Anyone <BR>

have a case this stubborn or have any suggestions?<BR>

<BR>

It's not that his lead hasn't reduced, but it's hover around the same <BR>

number for the past 10 months.  It's like he's re-accumulating lead, <BR>

but I can't imagine from where.<BR>

<BR>

Thanks for any help, <BR>

Sheri  <BR>

=======================================================<BR>

[Guest guest]

> > My understanding is, that the DMSA takes the lead out of the blood

and that

> > the lead then leaks out of the bones back into the blood.

> >

>

> Could this actually happen?

yep.

> Wouldn't it mean the disintegration of bone?

no, bones (and every other body tissue) are replacing cells

all the time.

> would any body explain this to me? I'm not being sarcastic, am

geniunely

> wondering. Nicky has lead.

My understanding is that lead is stored in the bones. What

happens is that as the REST of the body (and blood) get

cleared of lead, SOME of the lead in the bones will get

redistributed. I think of it as a process of equalibrium.

The amount of lead is " being equalized " or rebalanced.

Then some more gets chelated out. Then some more rebalancing

as lead from bones is moved out.

Bones detox RELATIVELY slower than other body tissues, so

that is why this results in a long slow process.

>

> What about trying EDTA instead of DMSA? Would that make any

difference?

>

No, the body mechanisms would be the same, regardless of

chelation agent. There may be other reasons to prefer one

or another chelation agent, but it won't make the bones

drop all the lead right away.

best,

Moria

[Guest guest]

Hopefully the lead would be replaced with calcium...???

Re: [ ] Can't get the lead out!!

>

> In a message dated 29/6/03 5:43:44 am, dagmarjahr@... writes:

>

>

> > My understanding is, that the DMSA takes the lead out of the blood and

that

> > the lead then leaks out of the bones back into the blood.

> >

>

> Could this actually happen? Wouldn't it mean the disintegration of bone?

> would any body explain this to me? I'm not being sarcastic, am geniunely

> wondering. Nicky has lead.

>

> What about trying EDTA instead of DMSA? Would that make any difference?

>

> marti

>

>

>

[Guest guest]

Hi

I started chelation knowing I'd be at it for years. I figure on 70+ plus

rounds of 3/11 followed by another couple years at once

monthly..............only

done 35. Sam has high Lead and other stuff hence the 70 rounds 3/11. I

mporvemnts are small, subtle but sustained, repeat after me .............this is

a

marathon not a sprint LOL!

Mandi in UK

[Guest guest]

>

> My understanding is that lead is stored in the bones. What

> happens is that as the REST of the body (and blood) get

> cleared of lead, SOME of the lead in the bones will get

> redistributed. I think of it as a process of equalibrium.

> The amount of lead is " being equalized " or rebalanced.

> Then some more gets chelated out. Then some more rebalancing

> as lead from bones is moved out.

>

> Bones detox RELATIVELY slower than other body tissues, so

> that is why this results in a long slow process.

>

Here's another extract from

http://www.leadpoison.net/treat/american.htm

Our understanding of the pharmacokinetics of lead and its alteration

by chelating agents is rudimentary. Human lead pharmacokinetics has

been studied in small series.4 Isotopic lead administered at, low

doses in adult human subjects revealed that lead has an extremely

long terminal elimination half-life in blood of more than 30 days and

similarly long rates of uptake into tissue. Rates of elimination from

bone were so long that they could not be determined but are estimated

in years. It is therefore extremely difficult to estimate the total

body burden of lead on the basis of blood lead concentrations. In the

face of increases in lead intake, the blood concentration may be

artificially elevated until equilibration occurs. Similarly, drug

therapy that removes lead primarily from the blood or soft tissue may

have a limited impact on the total body burden but may lower the

blood lead concentration until deeply stored lead reequilibrates into

the circulation. It may be predicted, then, that chelation of

chronically lead-ex-posed individuals would be followed by

significant reequilibration and that long-term therapy may be

necessary to assure that total body burden has been reduced despite

falling serum concentrations of lead. Concerns about the safety of

chelation have focused on experimental evidence from animals that

chelating agents may cause lead distribution into certain body

tissues, particularly the brain,5 These results may not apply to

children, who typically have chronic, low-level exposure. The long-

term outcome after treatment with succimer is the subject of an

ongoing multicenter study sponsored by the National Institute of

Environmental Health Sciences.

[Guest guest]

In a message dated 30/6/03 1:29:23 am, mycowbells@... writes:

> Concerns about the safety of

> chelation have focused on experimental evidence from animals that

> chelating agents may cause lead distribution into certain body

> tissues, particularly the brain,5

>

Oh great....