Re: Plasma Cysteine/Sulfate Test Results-Please Help Analyze

[Guest guest]

Here's how to interpret the plasma cysteine and sulfate:

http://health.groups.yahoo.com/group/Autism-Mercury/message/57707

W.

[Guest guest]

Here's how to interpret the plasma cysteine and sulfate:

http://health.groups.yahoo.com/group/Autism-Mercury/message/57707

W.

[Guest guest]

Here's how to interpret the plasma cysteine and sulfate:

http://health.groups.yahoo.com/group/Autism-Mercury/message/57707

W.

[Guest guest]

>

> Here's how to interpret the plasma cysteine and sulfate:

>

> http://health.groups.yahoo.com/group/Autism-Mercury/message/57707

>

> W.

>

Thanks, (my name's , too!). I had seen that post by Andy,

but I didn't understand it. For example, I am case 1. My Questions are

in CAPS:

The interpretation depends on the following TWO results:

Plasma cysteine, and plasma sulfate.

The possible combinations are:

1. Cys low SO4 low

2. Cys normal SO4 low

3. Cys elevated SO4 low

4. Cys low SO4 normal

5. Cys normal SO4 normal

6. Cys elevated SO4 normal

7. Cys low SO4 elevated

8. Cys normal SO4 elevated

9. Cys elevated SO4 elevated

In cases 1, 4 and 7 thiols and their precursors should be maximized in

the diet and supplements IF and ONLY if the patient shows obvious

improvement with doing this.

WHAT ARE THIOLS AND THEIR PRECURSORS? IS THERE A SUPPLEMENT CALLED

THIOL? ARE THIOLS SUPPLEMENTS LIKE GLUTATHIONE OR IT'S PRECURSOR,

N-ACETYL CYSTEINE? WHAT FOODS ARE THIOLS IN?

In cases 1, 2 and 3 sulfate should be supplemented orally,

transdermally and by epsom salt bath.

WHAT TYPE OF SULFATE ORALLY?

In cases 1, 2 and 3 the pool of available sulfate is inadequate and

dietary restriction of things requiring sulfation may be helpful.

WHAT FOODS REQUIRE SULFATION?

In all cases, how the person responds to these interventions is a more

accurate guide to appropriate treatment than are numbers on a piece of

paper that comes from a laboratory.

Low = sulfate depleted, it isn't there to use when needed. Do anything

and everything to increase sulfate levels. both supplementation and

dietary exclusion help here.

> Do low levels in both blood and urine just mean that they need to

add more sulphury foods to the diet?

No, this is never appropriate under any circumstances. This is not

the way to increase sulfate. When you want more sulfate, give more

sulfate. Decide what to do with thiols depending on cysteine level.

DOES THIS MEAN I SHOULD AVOID SULPHUR FOODS SUCH AS ONIONS, GARLIC, ???

In cases where cysteine is low and sulfate is low, or cysteine is high

and sulfate is high, there is some ambiguity as to what is going on.

I'M STILL CONFUSED.

[Guest guest]

I had seen that post by Andy,

> but I didn't understand it. For example, I am case 1. My Questions

are

> in CAPS:

>

> The interpretation depends on the following TWO results:

>

> Plasma cysteine, and plasma sulfate.

>

> The possible combinations are:

>

> 1. Cys low SO4 low

> 2. Cys normal SO4 low

> 3. Cys elevated SO4 low

> 4. Cys low SO4 normal

> 5. Cys normal SO4 normal

> 6. Cys elevated SO4 normal

> 7. Cys low SO4 elevated

> 8. Cys normal SO4 elevated

> 9. Cys elevated SO4 elevated

>

> In cases 1, 4 and 7 thiols and their precursors should be

maximized in

> the diet and supplements IF and ONLY if the patient shows obvious

> improvement with doing this.

>

> WHAT ARE THIOLS AND THEIR PRECURSORS?

TK--- you can look this up very easily with a google search.

bacically Thiols are sulfer compounds. -

http://en.wikipedia.org/wiki/Thiol

IS THERE A SUPPLEMENT CALLED

> THIOL?

TK--- no

ARE THIOLS SUPPLEMENTS LIKE GLUTATHIONE OR IT'S PRECURSOR,

> N-ACETYL CYSTEINE?

TK--- they are a couple of them

WHAT FOODS ARE THIOLS IN?

TK-- many

>

> In cases 1, 2 and 3 sulfate should be supplemented orally,

> transdermally and by epsom salt bath.

>

> WHAT TYPE OF SULFATE ORALLY?

TK--- epsom salt and other sulfates like glucosamine sulfate

>

> In cases 1, 2 and 3 the pool of available sulfate is inadequate and

> dietary restriction of things requiring sulfation may be helpful.

>

> WHAT FOODS REQUIRE SULFATION?

TK-- You may want to review this, it may help explain the process

further - I do not know if it is entirely correct but it may help

explain things - http://www.tuberose.com/Liver_Detoxification.html

>

> In all cases, how the person responds to these interventions is a

more

> accurate guide to appropriate treatment than are numbers on a

piece of

> paper that comes from a laboratory.

>

> Low = sulfate depleted, it isn't there to use when needed. Do

anything

> and everything to increase sulfate levels. both supplementation and

> dietary exclusion help here.

>

> > Do low levels in both blood and urine just mean that they need to

> add more sulphury foods to the diet?

>

> No, this is never appropriate under any circumstances. This is not

> the way to increase sulfate. When you want more sulfate, give more

> sulfate. Decide what to do with thiols depending on cysteine level.

>

> DOES THIS MEAN I SHOULD AVOID SULPHUR FOODS SUCH AS ONIONS,

GARLIC, ???

TK--- most people need to some people don't, exclusion - then trial

and error are the only way to really tell if they make you worse or

make you feel better, for most they make them worse which is why in

general they are recommended not to use.

>

> In cases where cysteine is low and sulfate is low, or cysteine is

high

> and sulfate is high, there is some ambiguity as to what is going

on.

>

> I'M STILL CONFUSED.

TK--- Yes it cam be

>

[Guest guest]

I had seen that post by Andy,

> but I didn't understand it. For example, I am case 1. My Questions

are

> in CAPS:

>

> The interpretation depends on the following TWO results:

>

> Plasma cysteine, and plasma sulfate.

>

> The possible combinations are:

>

> 1. Cys low SO4 low

> 2. Cys normal SO4 low

> 3. Cys elevated SO4 low

> 4. Cys low SO4 normal

> 5. Cys normal SO4 normal

> 6. Cys elevated SO4 normal

> 7. Cys low SO4 elevated

> 8. Cys normal SO4 elevated

> 9. Cys elevated SO4 elevated

>

> In cases 1, 4 and 7 thiols and their precursors should be

maximized in

> the diet and supplements IF and ONLY if the patient shows obvious

> improvement with doing this.

>

> WHAT ARE THIOLS AND THEIR PRECURSORS?

TK--- you can look this up very easily with a google search.

bacically Thiols are sulfer compounds. -

http://en.wikipedia.org/wiki/Thiol

IS THERE A SUPPLEMENT CALLED

> THIOL?

TK--- no

ARE THIOLS SUPPLEMENTS LIKE GLUTATHIONE OR IT'S PRECURSOR,

> N-ACETYL CYSTEINE?

TK--- they are a couple of them

WHAT FOODS ARE THIOLS IN?

TK-- many

>

> In cases 1, 2 and 3 sulfate should be supplemented orally,

> transdermally and by epsom salt bath.

>

> WHAT TYPE OF SULFATE ORALLY?

TK--- epsom salt and other sulfates like glucosamine sulfate

>

> In cases 1, 2 and 3 the pool of available sulfate is inadequate and

> dietary restriction of things requiring sulfation may be helpful.

>

> WHAT FOODS REQUIRE SULFATION?

TK-- You may want to review this, it may help explain the process

further - I do not know if it is entirely correct but it may help

explain things - http://www.tuberose.com/Liver_Detoxification.html

>

> In all cases, how the person responds to these interventions is a

more

> accurate guide to appropriate treatment than are numbers on a

piece of

> paper that comes from a laboratory.

>

> Low = sulfate depleted, it isn't there to use when needed. Do

anything

> and everything to increase sulfate levels. both supplementation and

> dietary exclusion help here.

>

> > Do low levels in both blood and urine just mean that they need to

> add more sulphury foods to the diet?

>

> No, this is never appropriate under any circumstances. This is not

> the way to increase sulfate. When you want more sulfate, give more

> sulfate. Decide what to do with thiols depending on cysteine level.

>

> DOES THIS MEAN I SHOULD AVOID SULPHUR FOODS SUCH AS ONIONS,

GARLIC, ???

TK--- most people need to some people don't, exclusion - then trial

and error are the only way to really tell if they make you worse or

make you feel better, for most they make them worse which is why in

general they are recommended not to use.

>

> In cases where cysteine is low and sulfate is low, or cysteine is

high

> and sulfate is high, there is some ambiguity as to what is going

on.

>

> I'M STILL CONFUSED.

TK--- Yes it cam be

>

[Guest guest]

I had seen that post by Andy,

> but I didn't understand it. For example, I am case 1. My Questions

are

> in CAPS:

>

> The interpretation depends on the following TWO results:

>

> Plasma cysteine, and plasma sulfate.

>

> The possible combinations are:

>

> 1. Cys low SO4 low

> 2. Cys normal SO4 low

> 3. Cys elevated SO4 low

> 4. Cys low SO4 normal

> 5. Cys normal SO4 normal

> 6. Cys elevated SO4 normal

> 7. Cys low SO4 elevated

> 8. Cys normal SO4 elevated

> 9. Cys elevated SO4 elevated

>

> In cases 1, 4 and 7 thiols and their precursors should be

maximized in

> the diet and supplements IF and ONLY if the patient shows obvious

> improvement with doing this.

>

> WHAT ARE THIOLS AND THEIR PRECURSORS?

TK--- you can look this up very easily with a google search.

bacically Thiols are sulfer compounds. -

http://en.wikipedia.org/wiki/Thiol

IS THERE A SUPPLEMENT CALLED

> THIOL?

TK--- no

ARE THIOLS SUPPLEMENTS LIKE GLUTATHIONE OR IT'S PRECURSOR,

> N-ACETYL CYSTEINE?

TK--- they are a couple of them

WHAT FOODS ARE THIOLS IN?

TK-- many

>

> In cases 1, 2 and 3 sulfate should be supplemented orally,

> transdermally and by epsom salt bath.

>

> WHAT TYPE OF SULFATE ORALLY?

TK--- epsom salt and other sulfates like glucosamine sulfate

>

> In cases 1, 2 and 3 the pool of available sulfate is inadequate and

> dietary restriction of things requiring sulfation may be helpful.

>

> WHAT FOODS REQUIRE SULFATION?

TK-- You may want to review this, it may help explain the process

further - I do not know if it is entirely correct but it may help

explain things - http://www.tuberose.com/Liver_Detoxification.html

>

> In all cases, how the person responds to these interventions is a

more

> accurate guide to appropriate treatment than are numbers on a

piece of

> paper that comes from a laboratory.

>

> Low = sulfate depleted, it isn't there to use when needed. Do

anything

> and everything to increase sulfate levels. both supplementation and

> dietary exclusion help here.

>

> > Do low levels in both blood and urine just mean that they need to

> add more sulphury foods to the diet?

>

> No, this is never appropriate under any circumstances. This is not

> the way to increase sulfate. When you want more sulfate, give more

> sulfate. Decide what to do with thiols depending on cysteine level.

>

> DOES THIS MEAN I SHOULD AVOID SULPHUR FOODS SUCH AS ONIONS,

GARLIC, ???

TK--- most people need to some people don't, exclusion - then trial

and error are the only way to really tell if they make you worse or

make you feel better, for most they make them worse which is why in

general they are recommended not to use.

>

> In cases where cysteine is low and sulfate is low, or cysteine is

high

> and sulfate is high, there is some ambiguity as to what is going

on.

>

> I'M STILL CONFUSED.

TK--- Yes it cam be

>

[Guest guest]

>

> WHAT FOODS ARE THIOLS IN?

>

>

Lots of posts from Andy here:

http://home.earthlink.net/~moriam/ANDY_INDEX.html#sulfur

Partial list of high sulfur foods here:

http://health.groups.yahoo.com/group/Autism-Mercury/message/36183

J

(another !!)

[Guest guest]

>

> WHAT FOODS ARE THIOLS IN?

>

>

Lots of posts from Andy here:

http://home.earthlink.net/~moriam/ANDY_INDEX.html#sulfur

Partial list of high sulfur foods here:

http://health.groups.yahoo.com/group/Autism-Mercury/message/36183

J

(another !!)

[Guest guest]

This suggests you are one of the people who will feel better on a high sulfur

diet, and

taking high doses of ALA. Give it a try. Read about the " sulfur food reaction "

in Amalgam

Illness and be aware of it, it is not entirely obvious and simple.

Taking epsom salt baths, taking 1000 or more mcg a day of molybdenum, and not

eating

a lot of berries and fruit may also be helpful in terms of feeling good.

Andy

>

> I just received test results for the Great Smokies (now Genova) Detox

> Profile, which includes Plasma Cysteine and Plasma Sulfate. The doctor

> said the results were good... In other words, she didn't know how to

> interpret this test. I was not on a round when I took this test, but

> have done several rounds with DMPS (up to 75mg every 6 hours) and am

> on my second round with ALA (25mg every 3 hours) for 7 days. I would

> really appreciate any insight into what this all means. My results are:

>

> Phase I: Caffeine Clearance Results Reference Range

> 0.8 0.5-1.6 mL/min/kg

>

> Phase II: Plasma Cysteine 2.89 3.10-3.90 mg/dL

> Plasma Sulfate 2.98 4.80-5.30 mg/dL

>

> Glutathione Conjugation

> Acetaminophen Mercapturate %Recovery 5.9 5.6-11.4

>

> Glycine Conjugation

> Salicyluric Acid %Recovery 61 30-53

>

> Sulfation

> Acetaminophen Sulfate %Recovery 22 16-36

>

> Glucuronidation

> Acetamenophen Glucuronide %Recovery 42 27-56

>

> Ratios

> Plasma Cysteine/Sulfate 0.97 0.60-0.78

> Phase 1/Sulfation 3.6 3.5-13.0

> Phase 1/Glycination 1.3 1.3-3.5

> Phase 1/Glucuronidation 1.9 1.9-4.2

>

> Free Radical Markers

> Catechol %Recovery 0.014 <0.024

> 2,3 DHBA %Recovery 0.0032 <0.0072

> Urine Lipid Peroxides mmol/g Creat. 5.2 <10.0

> Glutathione micromol/L 633 >669

> Glutathione Peroxidase U/g Hb 15.8 9.0-20.0

> Superoxide Dismutase U/g Hb 3,629 5,275-16,662

>