Guest guest Posted January 23, 2006 Report Share Posted January 23, 2006 Hi Dawn, DQ2 and DQ8 are the main genes known to cause Celiac Disease. A person with CD can have either or both, and it only takes one copy to cause the disease. If he tested positive for DQ2, then he does carry the genetics to cause CD. Did they run the antibody blood tests on him?? There are also some lesser known genes that can cause gluten intolerance and so it is possible to still have problems with gluten even if a person were negative for DQ2 and DQ8. My daughter and I both carry one copy of DQ2 and one copy of DQ3, but my sons don't have DQ2 or 8. One has DQ1 & 3, and one has 2 copies of DQ3. They both get really sick from gluten too... nn ~Original Message~ I was wondering if anyone could give me any insight to genetic testing results. My son tested positive to DQ2 and negative to DQ8. The pediatrician is not sure what it means and the specialist is out sick, so any insight anyone has would be greatly appreciated. Thanks. Dawn Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 24, 2006 Report Share Posted January 24, 2006 All I know is that it is much more likely that you will get celiac if you have either one of those genes. I'm interested in the responses - I also have the DQ2 and not the DQ8. --Trudy San , CA "People who believe in absurdities will eventually commit atrocities." ~Voltaire -------------- Original message -------------- From: tdleighty@... I was wondering if anyone could give me any insight to genetic testing results. My son tested positive to DQ2 and negative to DQ8. The pediatrician is not sure what it means and the specialist is out sick, so any insight anyone has would be greatly appreciated. Thanks. Dawn Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 24, 2006 Report Share Posted January 24, 2006 Two of my four children have DQ2 and not DQ8 but so far neither one has celiac disease. I never had genetic testing done so don't know what I have but suspect at very least it's the DQ2. I'm wondering if this means that the other two still have a possibility, albeit lower risk, of having celiac too or no chance of getting celiacs (which is what the endochrinologist told us since she ordered all the tests). :-) in VA Re: DQ2 and DQ8 All I know is that it is much more likely that you will get celiac if you have either one of those genes. I'm interested in the responses - I also have the DQ2 and not the DQ8. --Trudy San , CA "People who believe in absurdities will eventually commit atrocities." ~Voltaire -------------- Original message -------------- From: tdleighty@... I was wondering if anyone could give me any insight to genetic testing results. My son tested positive to DQ2 and negative to DQ8. The pediatrician is not sure what it means and the specialist is out sick, so any insight anyone has would be greatly appreciated. Thanks. Dawn Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 24, 2006 Report Share Posted January 24, 2006 Two of my four children have DQ2 and not DQ8 but so far neither one has celiac disease. I never had genetic testing done so don't know what I have but suspect at very least it's the DQ2. I'm wondering if this means that the other two still have a possibility, albeit lower risk, of having celiac too or no chance of getting celiacs (which is what the endochrinologist told us since she ordered all the tests). :-) in VA Re: DQ2 and DQ8 All I know is that it is much more likely that you will get celiac if you have either one of those genes. I'm interested in the responses - I also have the DQ2 and not the DQ8. --Trudy San , CA "People who believe in absurdities will eventually commit atrocities." ~Voltaire -------------- Original message -------------- From: tdleighty@... I was wondering if anyone could give me any insight to genetic testing results. My son tested positive to DQ2 and negative to DQ8. The pediatrician is not sure what it means and the specialist is out sick, so any insight anyone has would be greatly appreciated. Thanks. Dawn Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 24, 2006 Report Share Posted January 24, 2006 Two of my four children have DQ2 and not DQ8 but so far neither one has celiac disease. I never had genetic testing done so don't know what I have but suspect at very least it's the DQ2. I'm wondering if this means that the other two still have a possibility, albeit lower risk, of having celiac too or no chance of getting celiacs (which is what the endochrinologist told us since she ordered all the tests). :-) in VA Re: DQ2 and DQ8 All I know is that it is much more likely that you will get celiac if you have either one of those genes. I'm interested in the responses - I also have the DQ2 and not the DQ8. --Trudy San , CA "People who believe in absurdities will eventually commit atrocities." ~Voltaire -------------- Original message -------------- From: tdleighty@... I was wondering if anyone could give me any insight to genetic testing results. My son tested positive to DQ2 and negative to DQ8. The pediatrician is not sure what it means and the specialist is out sick, so any insight anyone has would be greatly appreciated. Thanks. Dawn Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 24, 2006 Report Share Posted January 24, 2006 You can't rule it out. I was diagnosed, even though my blood tests were normal except one "slightly elevated" and I had a negative biopsy. Watch for some of the non *classic* symptoms like dark circles under the eyes, anxiety, mood swings, etc. The problem for me is that most of my symptoms take time to manifest. After my body went through the *trauma* of pregnancy, I started having the bloating and big D too. --Trudy San , CA "People who believe in absurdities will eventually commit atrocities." ~Voltaire -------------- Original message -------------- Two of my four children have DQ2 and not DQ8 but so far neither one has celiac disease. I never had genetic testing done so don't know what I have but suspect at very least it's the DQ2. I'm wondering if this means that the other two still have a possibility, albeit lower risk, of having celiac too or no chance of getting celiacs (which is what the endochrinologist told us since she ordered all the tests). :-) in VA Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 24, 2006 Report Share Posted January 24, 2006 DQ2 is the gene most commonly associated with Celiac Disease, DQ8 being less common. You only need one gene to have the ability to DEVELOP Celiac Disease - Having the gene does not mean you have Celiac Disease. Many people have DQ2 or DQ8, and never get Celiac Disease. Suzie RE: DQ2 and DQ8 Hi Dawn, DQ2 and DQ8 are the main genes known to cause Celiac Disease. A person with CD can have either or both, and it only takes one copy to cause the disease. If he tested positive for DQ2, then he does carry the genetics to cause CD. Did they run the antibody blood tests on him?? There are also some lesser known genes that can cause gluten intolerance and so it is possible to still have problems with gluten even if a person were negative for DQ2 and DQ8. My daughter and I both carry one copy of DQ2 and one copy of DQ3, but my sons don't have DQ2 or 8. One has DQ1 & 3, and one has 2 copies of DQ3. They both get really sick from gluten too... nn ~Original Message~ I was wondering if anyone could give me any insight to genetic testing results. My son tested positive to DQ2 and negative to DQ8. The pediatrician is not sure what it means and the specialist is out sick, so any insight anyone has would be greatly appreciated. Thanks. Dawn Quote Link to comment Share on other sites More sharing options...
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