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Hysteroid Dysphoria

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Before I comment on what a phony crock of shit this nonsense is, here

it is for you to read:

http://psychiatry.mc.duke.edu/Residents/Depression.html

Author:

Aiken, M.D.

Hysteroid Dysphoria

Definition:

A subgroup of depressed patients, usually women

with histrionic character traits, whose depressions

are often precipitated by rejection or loss of

romantic attachment. These episodes are brief, improve

with attention or praise, and are characterized by

oversleeping, overeating (esp. sweets), and inertia

or leaden paralysis.

History:

Proposed by Klein in 1969, he conceptualized

hysteroid dysphoria as a state rather than trait

condition with a differential response to MAOIs1.

Klein argued for its inclusion in the 1980 DSM-III,

but it was left out due to a lack of formal data.

Spitzer then tested its validity in 1982 by

sending a brief questionnaire to 4,000 psychiatrists

which asked them to examine two of their

patients with mild depression for hysteroid

features. " Syndromal validity " was not found, meaning that

the 4 basic hysteroid-dysphoric features did not

significantly associate together2. Spitzer and Klein

continued to argue over these results3, but with

Spitzer at the helm of the DSM task force, hysteroid

dyphoria was ultimately left out of future editions.

Hysteroid dysphoria exhibits overlap with atypical

depression, bipolar-II disorder, cyclothymia and

personality disorders. While several studies have

found evidence of a differential effect of MAOIs on

hysteroid dysphoria1,4, this difference was not

found in a study that separated atypical from

hysteroid depressives5.

Fun Fact:

The craving for chocolate may come from

phenylethylamine, which facilitates

l-tryptophan uptake, potentially increasing

endogenous antidepressants.

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