Re: can liver cirrhosis occur almost immediately after PSC diagnosis ?

[Guest guest]

I obviously don't know what is going on with your husband, but I can say that when I became symptomatic both my CA19-9 and CEA were far above normal. Both came down after the obstruction was removed and are now in the lower half of the scale.

About the cirrhosis I can't tell you a lot. It appears to me he probably had the cirrhosis before the dx and they are now finding out about it. But that is just a guess.

Shalom from the holy land.

-----Original Message-----From: [mailto: ]On Behalf Of prichsySent: Monday, October 23, 2006 8:17 AMTo: Subject: can liver cirrhosis occur almost immediately after PSC diagnosis ?

Hubby is doing his ERGC today, but Hepatologist thinks it won't be a dominant stricture, rather that there is liver scarring which is most likely liver cirrhosis which is giving him the symptoms of obstruction.Also, hubby's CA19-9 is elevated and the CEA is elevated too, so I am so so so worried.........Please pray with me...Need it desperately.

[Guest guest]

I obviously don't know what is going on with your husband, but I can say that when I became symptomatic both my CA19-9 and CEA were far above normal. Both came down after the obstruction was removed and are now in the lower half of the scale.

About the cirrhosis I can't tell you a lot. It appears to me he probably had the cirrhosis before the dx and they are now finding out about it. But that is just a guess.

Shalom from the holy land.

-----Original Message-----From: [mailto: ]On Behalf Of prichsySent: Monday, October 23, 2006 8:17 AMTo: Subject: can liver cirrhosis occur almost immediately after PSC diagnosis ?

Hubby is doing his ERGC today, but Hepatologist thinks it won't be a dominant stricture, rather that there is liver scarring which is most likely liver cirrhosis which is giving him the symptoms of obstruction.Also, hubby's CA19-9 is elevated and the CEA is elevated too, so I am so so so worried.........Please pray with me...Need it desperately.

[Guest guest]

ERCP done. No cirrhosis.Dominant stricture as well as other

strictures found. Temporary stent done. Balloon... to be done in

some weeks.Also, brushings were taken. Thankfully they were wrong

about the cirrhosis. Can't understand why the MRCP didn't catch the

dominant stricture.Hopefully brushings will be negative for cancer

and the ca19 and cea will get back to normal range now the

obstruction is cleared.

> I obviously don't know what is going on with your husband, but I

can say

> that when I became symptomatic both my CA19-9 and CEA were far

above normal.

> Both came down after the obstruction was removed and are now in

the lower

> half of the scale.

>

> About the cirrhosis I can't tell you a lot. It appears to me he

probably had

> the cirrhosis before the dx and they are now finding out about it.

But that

> is just a guess.

>

> Shalom from the holy land.

>

>

> can liver cirrhosis occur almost

immediately after

> PSC diagnosis ?

>

>

> Hubby is doing his ERGC today, but Hepatologist thinks it won't

be a

> dominant stricture, rather that there is liver scarring which is

most

> likely liver cirrhosis which is giving him the symptoms of

obstruction.

> Also, hubby's CA19-9 is elevated and the CEA is elevated too, so

I am

> so so so worried.........

> Please pray with me...

> Need it desperately.

>

[Guest guest]

ERCP done. No cirrhosis.Dominant stricture as well as other

strictures found. Temporary stent done. Balloon... to be done in

some weeks.Also, brushings were taken. Thankfully they were wrong

about the cirrhosis. Can't understand why the MRCP didn't catch the

dominant stricture.Hopefully brushings will be negative for cancer

and the ca19 and cea will get back to normal range now the

obstruction is cleared.

> I obviously don't know what is going on with your husband, but I

can say

> that when I became symptomatic both my CA19-9 and CEA were far

above normal.

> Both came down after the obstruction was removed and are now in

the lower

> half of the scale.

>

> About the cirrhosis I can't tell you a lot. It appears to me he

probably had

> the cirrhosis before the dx and they are now finding out about it.

But that

> is just a guess.

>

> Shalom from the holy land.

>

>

> can liver cirrhosis occur almost

immediately after

> PSC diagnosis ?

>

>

> Hubby is doing his ERGC today, but Hepatologist thinks it won't

be a

> dominant stricture, rather that there is liver scarring which is

most

> likely liver cirrhosis which is giving him the symptoms of

obstruction.

> Also, hubby's CA19-9 is elevated and the CEA is elevated too, so

I am

> so so so worried.........

> Please pray with me...

> Need it desperately.

>

[Guest guest]

ERCP done. No cirrhosis.Dominant stricture as well as other

strictures found. Temporary stent done. Balloon... to be done in

some weeks.Also, brushings were taken. Thankfully they were wrong

about the cirrhosis. Can't understand why the MRCP didn't catch the

dominant stricture.Hopefully brushings will be negative for cancer

and the ca19 and cea will get back to normal range now the

obstruction is cleared.

> I obviously don't know what is going on with your husband, but I

can say

> that when I became symptomatic both my CA19-9 and CEA were far

above normal.

> Both came down after the obstruction was removed and are now in

the lower

> half of the scale.

>

> About the cirrhosis I can't tell you a lot. It appears to me he

probably had

> the cirrhosis before the dx and they are now finding out about it.

But that

> is just a guess.

>

> Shalom from the holy land.

>

>

> can liver cirrhosis occur almost

immediately after

> PSC diagnosis ?

>

>

> Hubby is doing his ERGC today, but Hepatologist thinks it won't

be a

> dominant stricture, rather that there is liver scarring which is

most

> likely liver cirrhosis which is giving him the symptoms of

obstruction.

> Also, hubby's CA19-9 is elevated and the CEA is elevated too, so

I am

> so so so worried.........

> Please pray with me...

> Need it desperately.

>

[Guest guest]

Good news about the cirrhosis, I am now waiting for the good news about the brushings. If I remember well both CEA and CA19-9 took a while to go down. ERCP sounds so scary at first, but once you "get used" to the idea, and see how helpful it can be, you will proceed to have a love/hate relationship with it.

can liver cirrhosis occur almost immediately after> PSC diagnosis ?> > > Hubby is doing his ERGC today, but Hepatologist thinks it won't be a> dominant stricture, rather that there is liver scarring which is most> likely liver cirrhosis which is giving him the symptoms of obstruction.> Also, hubby's CA19-9 is elevated and the CEA is elevated too, so I am> so so so worried.........> Please pray with me...> Need it desperately.>

[Guest guest]

Good news about the cirrhosis, I am now waiting for the good news about the brushings. If I remember well both CEA and CA19-9 took a while to go down. ERCP sounds so scary at first, but once you "get used" to the idea, and see how helpful it can be, you will proceed to have a love/hate relationship with it.

can liver cirrhosis occur almost immediately after> PSC diagnosis ?> > > Hubby is doing his ERGC today, but Hepatologist thinks it won't be a> dominant stricture, rather that there is liver scarring which is most> likely liver cirrhosis which is giving him the symptoms of obstruction.> Also, hubby's CA19-9 is elevated and the CEA is elevated too, so I am> so so so worried.........> Please pray with me...> Need it desperately.>

[Guest guest]

Sounds like good news! MRCP is still relatively new, and generally works fine

for diagnositic purposes. However, if you need therapy (balloon dilatation and

stenting for elevated LFTs, jaundice, cholangitis, etc.), there's no substitute

for an ERCP.

Of course, I've never had an MRCP, so my thoughts are somewhat suspect.

Arne

============================================================

ERCP done. No cirrhosis.Dominant stricture as well as other

strictures found. Temporary stent done. Balloon... to be done in some

weeks.Also, brushings were taken. Thankfully they were wrong about the

cirrhosis. Can't understand why the MRCP didn't catch the dominant

stricture.Hopefully brushings will be negative for cancer and the ca19 and cea

will get back to normal range now the obstruction is cleared.

[Guest guest]

Sounds like good news! MRCP is still relatively new, and generally works fine

for diagnositic purposes. However, if you need therapy (balloon dilatation and

stenting for elevated LFTs, jaundice, cholangitis, etc.), there's no substitute

for an ERCP.

Of course, I've never had an MRCP, so my thoughts are somewhat suspect.

Arne

============================================================

ERCP done. No cirrhosis.Dominant stricture as well as other

strictures found. Temporary stent done. Balloon... to be done in some

weeks.Also, brushings were taken. Thankfully they were wrong about the

cirrhosis. Can't understand why the MRCP didn't catch the dominant

stricture.Hopefully brushings will be negative for cancer and the ca19 and cea

will get back to normal range now the obstruction is cleared.

[Guest guest]

That's great, congrats. We're all hoping the brushings turn out

negative as well. Meanwhile, I know what you mean about the MRCP - my

husband's MRCP was entirely normal as well and then the liver biopsy

came back with Stage 2-3 fibrosis, so I'm less impressed with that tool

than others. best,

nina

husband PSC 4/06

>

> ERCP done. No cirrhosis.Dominant stricture as well as other

> strictures found. Temporary stent done. Balloon... to be done in

> some weeks.Also, brushings were taken. Thankfully they were wrong

> about the cirrhosis. Can't understand why the MRCP didn't catch the

> dominant stricture.Hopefully brushings will be negative for cancer

> and the ca19 and cea will get back to normal range now the

> obstruction is cleared.

[Guest guest]

>

> ERCP done. No cirrhosis.Dominant stricture as well as other

> strictures found. Temporary stent done. Balloon... to be done in

> some weeks.Also, brushings were taken. Thankfully they were wrong

> about the cirrhosis.

Great all went well, is your husband feeling OK.

Good luck for the future.

Best wishes , from the bottom of the world in New Zealand.

[Guest guest]

>

> ERCP done. No cirrhosis.Dominant stricture as well as other

> strictures found. Temporary stent done. Balloon... to be done in

> some weeks.Also, brushings were taken. Thankfully they were wrong

> about the cirrhosis.

Great all went well, is your husband feeling OK.

Good luck for the future.

Best wishes , from the bottom of the world in New Zealand.

[Guest guest]

>

> ERCP done. No cirrhosis.Dominant stricture as well as other

> strictures found. Temporary stent done. Balloon... to be done in

> some weeks.Also, brushings were taken. Thankfully they were wrong

> about the cirrhosis.

Great all went well, is your husband feeling OK.

Good luck for the future.

Best wishes , from the bottom of the world in New Zealand.

[Guest guest]

Good that the ERCP went well. From his symptoms alone one might have suspected a

dominant stricture. Do have him monitor his temperature for the next few days.

MRCP doesn't catch everything. It can be done in several ways, though I don't

understand

the technicalities. But there are differences in the contrast, and also in the

delay and

weighting of the parameters. If you can talk with the radiologist before it can

help him/her

to know what to look for. Mine a year ago did indicate a stricture, but this was

inferred

from the pooling of bile in the ducts above, it didn't show the actual narrowed

place. In

fact the stricture was not dominant, and still isn't, but it is pretty narrow.

MRCP very

clearly showed the atrophy of the left lobe, something that ERCP can't. So from

my

experience it was useful- or at least would have been had the stricture been

treatable. We

make another attempt Friday with the new and improved " spy scope " .

Martha (MA)

> ERCP done. No cirrhosis.Dominant stricture as well as other

> strictures found.

Can't understand why the MRCP didn't catch the

> dominant stricture.