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Thanks for relating/Katy

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Beading of the bile ducts is a common finding with PSC. Basically, there's

a narrowing, followed by a " ballooning " , followed by a narrowing, etc. The

standard " rule of thumb " is that PSC probably started 10 years before any

symptoms, so it is an indication of progression, but not a very good one.

The endoscopic procedure is probably an ERCP (Endoscopic Retrograde

Cholangiopancreatography), the predecessor of MRCP. If they are suggesting

an ERCP, the PSC is probably most prominent in the common bile duct, where

they can access it (as opposed to ducts within the liver). They will most

likely be able to insert a balloon catheter and expand the affected portion

of the bile duct. They may insert a stent (small tube) to keep the duct

open while it heals to the new diameter. See

http://digestive.niddk.nih.gov/ddiseases/pubs/ercp/index.htm for a more

thorough explanation.

This typically works pretty well. I had my last ERCP in 2001 - I've been

symptom free since. Some people require frequent ERCPs, some don't. The

most common complication is pancreatitis, a painful inflammation of the

pancreas. He should not be released until that is ruled out. In my case,

it occurred several hours after the ERCP, and resulted in an additional 4-5

days in the hospital. They really don't know why it happens, and efforts to

eliminate that complication have not been very successful.

Hope this helps.

Arne

55 - UC 1977, PSC 2000

Alive and (mostly) well in Minnesota

________________________________

From: [mailto: ] On

Behalf Of Katy Kelley

Hi -

I just found out today that my son's possible diagnosis of PSC is a reality.

There goes that little hope I was cherishing... But he feels fine, he hasn't

had any symptoms at all, so now i guess we hope that continues longer

rather than shorter time, and that research will develop something, and that

i can be tough enough to support him through whatever comes....

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Share on other sites

Beading of the bile ducts is a common finding with PSC. Basically, there's

a narrowing, followed by a " ballooning " , followed by a narrowing, etc. The

standard " rule of thumb " is that PSC probably started 10 years before any

symptoms, so it is an indication of progression, but not a very good one.

The endoscopic procedure is probably an ERCP (Endoscopic Retrograde

Cholangiopancreatography), the predecessor of MRCP. If they are suggesting

an ERCP, the PSC is probably most prominent in the common bile duct, where

they can access it (as opposed to ducts within the liver). They will most

likely be able to insert a balloon catheter and expand the affected portion

of the bile duct. They may insert a stent (small tube) to keep the duct

open while it heals to the new diameter. See

http://digestive.niddk.nih.gov/ddiseases/pubs/ercp/index.htm for a more

thorough explanation.

This typically works pretty well. I had my last ERCP in 2001 - I've been

symptom free since. Some people require frequent ERCPs, some don't. The

most common complication is pancreatitis, a painful inflammation of the

pancreas. He should not be released until that is ruled out. In my case,

it occurred several hours after the ERCP, and resulted in an additional 4-5

days in the hospital. They really don't know why it happens, and efforts to

eliminate that complication have not been very successful.

Hope this helps.

Arne

55 - UC 1977, PSC 2000

Alive and (mostly) well in Minnesota

________________________________

From: [mailto: ] On

Behalf Of Katy Kelley

Hi -

I just found out today that my son's possible diagnosis of PSC is a reality.

There goes that little hope I was cherishing... But he feels fine, he hasn't

had any symptoms at all, so now i guess we hope that continues longer

rather than shorter time, and that research will develop something, and that

i can be tough enough to support him through whatever comes....

Link to comment
Share on other sites

Beading of the bile ducts is a common finding with PSC. Basically, there's

a narrowing, followed by a " ballooning " , followed by a narrowing, etc. The

standard " rule of thumb " is that PSC probably started 10 years before any

symptoms, so it is an indication of progression, but not a very good one.

The endoscopic procedure is probably an ERCP (Endoscopic Retrograde

Cholangiopancreatography), the predecessor of MRCP. If they are suggesting

an ERCP, the PSC is probably most prominent in the common bile duct, where

they can access it (as opposed to ducts within the liver). They will most

likely be able to insert a balloon catheter and expand the affected portion

of the bile duct. They may insert a stent (small tube) to keep the duct

open while it heals to the new diameter. See

http://digestive.niddk.nih.gov/ddiseases/pubs/ercp/index.htm for a more

thorough explanation.

This typically works pretty well. I had my last ERCP in 2001 - I've been

symptom free since. Some people require frequent ERCPs, some don't. The

most common complication is pancreatitis, a painful inflammation of the

pancreas. He should not be released until that is ruled out. In my case,

it occurred several hours after the ERCP, and resulted in an additional 4-5

days in the hospital. They really don't know why it happens, and efforts to

eliminate that complication have not been very successful.

Hope this helps.

Arne

55 - UC 1977, PSC 2000

Alive and (mostly) well in Minnesota

________________________________

From: [mailto: ] On

Behalf Of Katy Kelley

Hi -

I just found out today that my son's possible diagnosis of PSC is a reality.

There goes that little hope I was cherishing... But he feels fine, he hasn't

had any symptoms at all, so now i guess we hope that continues longer

rather than shorter time, and that research will develop something, and that

i can be tough enough to support him through whatever comes....

Link to comment
Share on other sites

It's so good to hear that sometimes something works. The Drs haven't really

been a ray of sunshine, and we've only met the liver specialist, Tom Boyer,

once. So it's hard to tell if the lack of encouragement is just their

standard mode, or if something about my son's case looks esp. bad. I'm

pretty twitchy at the moment. I think Drs should be followed around by

communicator/counselor/question answerers, so after the Dr leads you out to

to the ledge and whisks away, there's someone there to talk you down.

I'm kicking myself for going to a lower level of coverage with my district's

HMO. I had the highest, verge-of-unaffordable coverage last year and we

didn't need it, so I backed it off this year. The only difference is in

coverage of hospital stays, so the proposed ECRP could be a problem. I'll

just hope for the best, but I'd rather they didn't chance making him sicker

while he needs to be finishing his last semester at college. He has to stay

well until he graduates and gets a job, or there's no health coverage at

all. Yikes. I have more worries than brain cells at the moment, and I

suspect I'm not really back to rational yet.

Sorry for rambling on. Thanks for the info - I'm making a file!

Katy

>

>Reply-To:

>To: < >

>Subject: RE: Thanks for relating/Katy

>Date: Wed, 30 Aug 2006 05:12:48 -0500

>

>Beading of the bile ducts is a common finding with PSC. Basically, there's

>a narrowing, followed by a " ballooning " , followed by a narrowing, etc. The

>standard " rule of thumb " is that PSC probably started 10 years before any

>symptoms, so it is an indication of progression, but not a very good one.

>

_________________________________________________________________

All-in-one security and maintenance for your PC. Get a free 90-day trial!

http://www.windowsonecare.com/trial.aspx?sc_cid=msn_hotmail

Link to comment
Share on other sites

It's so good to hear that sometimes something works. The Drs haven't really

been a ray of sunshine, and we've only met the liver specialist, Tom Boyer,

once. So it's hard to tell if the lack of encouragement is just their

standard mode, or if something about my son's case looks esp. bad. I'm

pretty twitchy at the moment. I think Drs should be followed around by

communicator/counselor/question answerers, so after the Dr leads you out to

to the ledge and whisks away, there's someone there to talk you down.

I'm kicking myself for going to a lower level of coverage with my district's

HMO. I had the highest, verge-of-unaffordable coverage last year and we

didn't need it, so I backed it off this year. The only difference is in

coverage of hospital stays, so the proposed ECRP could be a problem. I'll

just hope for the best, but I'd rather they didn't chance making him sicker

while he needs to be finishing his last semester at college. He has to stay

well until he graduates and gets a job, or there's no health coverage at

all. Yikes. I have more worries than brain cells at the moment, and I

suspect I'm not really back to rational yet.

Sorry for rambling on. Thanks for the info - I'm making a file!

Katy

>

>Reply-To:

>To: < >

>Subject: RE: Thanks for relating/Katy

>Date: Wed, 30 Aug 2006 05:12:48 -0500

>

>Beading of the bile ducts is a common finding with PSC. Basically, there's

>a narrowing, followed by a " ballooning " , followed by a narrowing, etc. The

>standard " rule of thumb " is that PSC probably started 10 years before any

>symptoms, so it is an indication of progression, but not a very good one.

>

_________________________________________________________________

All-in-one security and maintenance for your PC. Get a free 90-day trial!

http://www.windowsonecare.com/trial.aspx?sc_cid=msn_hotmail

Link to comment
Share on other sites

It's so good to hear that sometimes something works. The Drs haven't really

been a ray of sunshine, and we've only met the liver specialist, Tom Boyer,

once. So it's hard to tell if the lack of encouragement is just their

standard mode, or if something about my son's case looks esp. bad. I'm

pretty twitchy at the moment. I think Drs should be followed around by

communicator/counselor/question answerers, so after the Dr leads you out to

to the ledge and whisks away, there's someone there to talk you down.

I'm kicking myself for going to a lower level of coverage with my district's

HMO. I had the highest, verge-of-unaffordable coverage last year and we

didn't need it, so I backed it off this year. The only difference is in

coverage of hospital stays, so the proposed ECRP could be a problem. I'll

just hope for the best, but I'd rather they didn't chance making him sicker

while he needs to be finishing his last semester at college. He has to stay

well until he graduates and gets a job, or there's no health coverage at

all. Yikes. I have more worries than brain cells at the moment, and I

suspect I'm not really back to rational yet.

Sorry for rambling on. Thanks for the info - I'm making a file!

Katy

>

>Reply-To:

>To: < >

>Subject: RE: Thanks for relating/Katy

>Date: Wed, 30 Aug 2006 05:12:48 -0500

>

>Beading of the bile ducts is a common finding with PSC. Basically, there's

>a narrowing, followed by a " ballooning " , followed by a narrowing, etc. The

>standard " rule of thumb " is that PSC probably started 10 years before any

>symptoms, so it is an indication of progression, but not a very good one.

>

_________________________________________________________________

All-in-one security and maintenance for your PC. Get a free 90-day trial!

http://www.windowsonecare.com/trial.aspx?sc_cid=msn_hotmail

Link to comment
Share on other sites

10. Re: Thanks for relating/Katy

Posted by: " Katy Kelley " inkywretch42@... inkywretch42

Date: Wed Aug 30, 2006 4:43 pm (PDT)

The only difference is in

coverage of hospital stays, so the proposed ERCP could be a problem. I'll

just hope for the best, but I'd rather they didn't chance making him sicker

while he needs to be finishing his last semester at college. He has to stay

well until he graduates and gets a job, or there's no health coverage at

all. Yikes. I have more worries than brain cells at the moment, and I

suspect I'm not really back to rational yet.

Hi Katy, You and your son do not necessarily have to agree to an ERCP or you

may agree to it but after he graduates. You decision should be based on the

reasons the doctors have for wanting it done. Many doctors like to do an ERCP

for screening and monitoring reasons. This is because many doctors are more

familiar with ERCP that MRCP. Also they can take brushings of tissue, which

allows them to look for bile duct cancer. However, as Arne told you an ERCP can

cause painful and dangerous side effects. In addition to pancreatitis, and ERCP

can cause bile duct infections. On the other hand, if your son has symptoms of

bile duct blockage that are causing discomfort or health problems, an ERCP may

be needed to dilate one or more ducts to improve the flow of bile out of the

liver.

I urge you to ask your doctor to explain why he is recommending the ERCP and

whether or not this procedure is urgent. Please also ask him/her to discuss how

the risks balance against the benefits in your son's case. Just because he/she

wants to insert a stent or do a dilation does not mean your son needs one before

graduation. PSC is tricky, it may be progressing quickly or slowly. There is no

way to tell how long your son has had it.

My experience is a case in point. When I was first diagnosed I got a diagnostic

ERCP that included inserting a stent; 10 days later I was hospitalized with a

bile duct infection and needed an emergency ERCP to remove the stent. It is now

6 years since diagnosis and I never got another ERCP. Although the ERCP and MRCP

show major strictures in all extrahepatic bile ducts and total destruction of

ducts in my left lobe, I am asymptomatic except for fatigue and occasional

itching. My alk. phos is elevated but nothing else is. The point is don't

assume the worst and don't assume your son needs aggressive intervention such as

an ERCP.

If your doctor has little experience with PSC I would consider getting a second

opinion from a hepatologist who does have such experience. If you let us know

where you live, someone in the group may be able to refer you to an experienced,

competent doctor. Also, Mayo Clinic, Rochester is the best in the U.S.

I wish you and your son all the best for a slowly progressing disease and a

successful career.

(Sacramento) dx UC and PSC 2001.

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Thanks jennifer -

I added your info to my ever-expanding file! I'm not sure yet that they'll

want to do the ERCP; it was mentioned as a possibility. There wasn't any

mention of a stent, I don't think. I'm so glad to hear of your (mostly)

lack of symptoms; it gives me hope for Trev.

Since the onset of Crohn's in 2001 he's been seeing Dr. Fayed Ghishan, head

of pediatrics at Univ. Med. Center. Dr Ghishan referred him to Dr.

Boyer, also of UMC. Apparently he's pretty well known as a liver

specialist. I think he's supposed to be experienced with PSC. He mentioned

Urso but kinda shrugged it off, so that wasn't encouraging. He's not big on

encouragement, I think, like a lot of docs. You get just the facts, if

you're that lucky.

There's a Mayo clinic over in sdale; I was wondering if they're up on

the latest.

Thanks again,

Katy

>

>Reply-To:

>To:

>Subject: Thanks for relating/Katy

>Date: Thu, 31 Aug 2006 16:22:14 -0700

>

>

>10. Re: Thanks for relating/Katy

> Posted by: " Katy Kelley " inkywretch42@... inkywretch42

> Date: Wed Aug 30, 2006 4:43 pm (PDT)

>

>

>The only difference is in

>coverage of hospital stays, so the proposed ERCP could be a problem. I'll

>just hope for the best, but I'd rather they didn't chance making him sicker

>while he needs to be finishing his last semester at college. He has to

>stay

>well until he graduates and gets a job, or there's no health coverage at

>all. Yikes. I have more worries than brain cells at the moment, and I

>suspect I'm not really back to rational yet.

>

>

>Hi Katy, You and your son do not necessarily have to agree to an ERCP or

>you may agree to it but after he graduates. You decision should be based

>on the reasons the doctors have for wanting it done.

>

>

_________________________________________________________________

All-in-one security and maintenance for your PC. Get a free 90-day trial!

http://www.windowsonecare.com/trial.aspx?sc_cid=msn_hotmail

Link to comment
Share on other sites

Thanks jennifer -

I added your info to my ever-expanding file! I'm not sure yet that they'll

want to do the ERCP; it was mentioned as a possibility. There wasn't any

mention of a stent, I don't think. I'm so glad to hear of your (mostly)

lack of symptoms; it gives me hope for Trev.

Since the onset of Crohn's in 2001 he's been seeing Dr. Fayed Ghishan, head

of pediatrics at Univ. Med. Center. Dr Ghishan referred him to Dr.

Boyer, also of UMC. Apparently he's pretty well known as a liver

specialist. I think he's supposed to be experienced with PSC. He mentioned

Urso but kinda shrugged it off, so that wasn't encouraging. He's not big on

encouragement, I think, like a lot of docs. You get just the facts, if

you're that lucky.

There's a Mayo clinic over in sdale; I was wondering if they're up on

the latest.

Thanks again,

Katy

>

>Reply-To:

>To:

>Subject: Thanks for relating/Katy

>Date: Thu, 31 Aug 2006 16:22:14 -0700

>

>

>10. Re: Thanks for relating/Katy

> Posted by: " Katy Kelley " inkywretch42@... inkywretch42

> Date: Wed Aug 30, 2006 4:43 pm (PDT)

>

>

>The only difference is in

>coverage of hospital stays, so the proposed ERCP could be a problem. I'll

>just hope for the best, but I'd rather they didn't chance making him sicker

>while he needs to be finishing his last semester at college. He has to

>stay

>well until he graduates and gets a job, or there's no health coverage at

>all. Yikes. I have more worries than brain cells at the moment, and I

>suspect I'm not really back to rational yet.

>

>

>Hi Katy, You and your son do not necessarily have to agree to an ERCP or

>you may agree to it but after he graduates. You decision should be based

>on the reasons the doctors have for wanting it done.

>

>

_________________________________________________________________

All-in-one security and maintenance for your PC. Get a free 90-day trial!

http://www.windowsonecare.com/trial.aspx?sc_cid=msn_hotmail

Link to comment
Share on other sites

Thanks jennifer -

I added your info to my ever-expanding file! I'm not sure yet that they'll

want to do the ERCP; it was mentioned as a possibility. There wasn't any

mention of a stent, I don't think. I'm so glad to hear of your (mostly)

lack of symptoms; it gives me hope for Trev.

Since the onset of Crohn's in 2001 he's been seeing Dr. Fayed Ghishan, head

of pediatrics at Univ. Med. Center. Dr Ghishan referred him to Dr.

Boyer, also of UMC. Apparently he's pretty well known as a liver

specialist. I think he's supposed to be experienced with PSC. He mentioned

Urso but kinda shrugged it off, so that wasn't encouraging. He's not big on

encouragement, I think, like a lot of docs. You get just the facts, if

you're that lucky.

There's a Mayo clinic over in sdale; I was wondering if they're up on

the latest.

Thanks again,

Katy

>

>Reply-To:

>To:

>Subject: Thanks for relating/Katy

>Date: Thu, 31 Aug 2006 16:22:14 -0700

>

>

>10. Re: Thanks for relating/Katy

> Posted by: " Katy Kelley " inkywretch42@... inkywretch42

> Date: Wed Aug 30, 2006 4:43 pm (PDT)

>

>

>The only difference is in

>coverage of hospital stays, so the proposed ERCP could be a problem. I'll

>just hope for the best, but I'd rather they didn't chance making him sicker

>while he needs to be finishing his last semester at college. He has to

>stay

>well until he graduates and gets a job, or there's no health coverage at

>all. Yikes. I have more worries than brain cells at the moment, and I

>suspect I'm not really back to rational yet.

>

>

>Hi Katy, You and your son do not necessarily have to agree to an ERCP or

>you may agree to it but after he graduates. You decision should be based

>on the reasons the doctors have for wanting it done.

>

>

_________________________________________________________________

All-in-one security and maintenance for your PC. Get a free 90-day trial!

http://www.windowsonecare.com/trial.aspx?sc_cid=msn_hotmail

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