Re: Sorry another question

July 6, 2004

Hi Billie,

Proteinuria does not reflect remaining kidney function. Some people spill very

little protein right up until the end and other folks lose a lot of protein from

the very beginning. The reason you want to get urine protein under control is

to extend the useful live of the kidney. However, getting this under control

will not reverse existing scarring.

As Pierre reminded everyone recently, there are factors (namely immune

deposition) other than proteinuria that contribute to renal decline. However,

unlike immune deposition, which remains pretty uncontrollable, proteinuria can

be controlled in some people to a certain extent. When you are down to 18%

function, it's probably unlikely that you will regain a signifigant amount of

function left - so the emphasis is on preserving what you have.

Cy

vintagecrazy2003 wrote:

Once you loose down to 18% function is it possible if you lower

the protein in your urine you could regain some kidney function

with iga? I had the last neph. in my (6) Dr. group state that it is

possible to regain back up to 45-50% but never 100%-the others

never mentioned that before but this Dr. only saw me five

minutes-my 24 hr urine came back as 1/2 gr protein per day after

taking the cytoxan two weeks with the predisone when two

months ago it was 3 grams a day so that is a big change but my

creatitine was 2.9. What do you all think? Thanks Billie

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Thank you

July 6, 2004

Hi Billie,

Proteinuria does not reflect remaining kidney function. Some people spill very

little protein right up until the end and other folks lose a lot of protein from

the very beginning. The reason you want to get urine protein under control is

to extend the useful live of the kidney. However, getting this under control

will not reverse existing scarring.

As Pierre reminded everyone recently, there are factors (namely immune

deposition) other than proteinuria that contribute to renal decline. However,

unlike immune deposition, which remains pretty uncontrollable, proteinuria can

be controlled in some people to a certain extent. When you are down to 18%

function, it's probably unlikely that you will regain a signifigant amount of

function left - so the emphasis is on preserving what you have.

Cy

vintagecrazy2003 wrote:

Once you loose down to 18% function is it possible if you lower

the protein in your urine you could regain some kidney function

with iga? I had the last neph. in my (6) Dr. group state that it is

possible to regain back up to 45-50% but never 100%-the others

never mentioned that before but this Dr. only saw me five

minutes-my 24 hr urine came back as 1/2 gr protein per day after

taking the cytoxan two weeks with the predisone when two

months ago it was 3 grams a day so that is a big change but my

creatitine was 2.9. What do you all think? Thanks Billie

To edit your settings for the group, go to our Yahoo Group

home page:

http://groups.yahoo.com/group/iga-nephropathy/

To unsubcribe via email,

iga-nephropathy-unsubscribe

Visit our companion website at www.igan.ca. The site is entirely supported by

donations. If you would like to help, go to:

http://www.igan.ca/id62.htm

Thank you

July 6, 2004

Hi Billie,

Proteinuria does not reflect remaining kidney function. Some people spill very

little protein right up until the end and other folks lose a lot of protein from

the very beginning. The reason you want to get urine protein under control is

to extend the useful live of the kidney. However, getting this under control

will not reverse existing scarring.

As Pierre reminded everyone recently, there are factors (namely immune

deposition) other than proteinuria that contribute to renal decline. However,

unlike immune deposition, which remains pretty uncontrollable, proteinuria can

be controlled in some people to a certain extent. When you are down to 18%

function, it's probably unlikely that you will regain a signifigant amount of

function left - so the emphasis is on preserving what you have.

Cy

vintagecrazy2003 wrote:

Once you loose down to 18% function is it possible if you lower

the protein in your urine you could regain some kidney function

with iga? I had the last neph. in my (6) Dr. group state that it is

possible to regain back up to 45-50% but never 100%-the others

never mentioned that before but this Dr. only saw me five

minutes-my 24 hr urine came back as 1/2 gr protein per day after

taking the cytoxan two weeks with the predisone when two

months ago it was 3 grams a day so that is a big change but my

creatitine was 2.9. What do you all think? Thanks Billie

To edit your settings for the group, go to our Yahoo Group

home page:

http://groups.yahoo.com/group/iga-nephropathy/

To unsubcribe via email,

iga-nephropathy-unsubscribe

Visit our companion website at www.igan.ca. The site is entirely supported by

donations. If you would like to help, go to:

http://www.igan.ca/id62.htm

Thank you

July 6, 2004

Cy answered you quite well. At 18% it's more a game of how slow can you go

rather than how much can you get back. You might see a bit of improvement

if your function is being depressed by inflammation along with plain old

scaring. You can see a slight rise when the inflammation is under control.

It happened to me but we are talking like a 6-8% increase not the roughly

30% your doctor is saying you might gain back. I went from 35-37% up to

about 45% function after starting prednisone treatment. So far, with the

exception of severe temporary loss of function due to infection, I haven't

come across anyone who has gained back that amount with treatment.

Keeping the protein spill under control is going to help keep what

function you have left going for a while longer. The prednisone and cytoxan

will help with inflammation issues if there are any and you may see an

increase in function due to the inflammation being controlled.

Amy

Sorry another question

> Once you loose down to 18% function is it possible if you lower

> the protein in your urine you could regain some kidney function

> with iga? I had the last neph. in my (6) Dr. group state that it is

> possible to regain back up to 45-50% but never 100%-the others

> never mentioned that before but this Dr. only saw me five

> minutes-my 24 hr urine came back as 1/2 gr protein per day after

> taking the cytoxan two weeks with the predisone when two

> months ago it was 3 grams a day so that is a big change but my

> creatitine was 2.9. What do you all think? Thanks Billie

>

> To edit your settings for the group, go to our Yahoo Group

> home page:

> http://groups.yahoo.com/group/iga-nephropathy/

>

> To unsubcribe via email,

> iga-nephropathy-unsubscribe

> Visit our companion website at www.igan.ca. The site is entirely supported

by donations. If you would like to help, go to:

> http://www.igan.ca/id62.htm

>

> Thank you

>

July 6, 2004