Re: About fish oil, ACE inhibators, and Prednisone

[Guest guest]

About fish oil, ACE inhibators, and Prednisone

> Hello

> Thanks Pierre to have accepted me on this forum, since I am writing a

> novel. Not easy to combinate together school with writing, since

> writing involves a lot of research.

> But I am trying to finish my novel that I called " Kiriaki " . It'll be

> published in French. I hope to finish it quickly in order to publish

> it. Pierre, are you able to read French ?

> I am not here to discuss about my novel, but to ask you some

> questions. Since I come to this forum, I have noticed that at the

> begining of IgAN, doctors prescribe fish oil and ACE inhibators. I

> have compared with what nephs do, in France at the begining of IgAN

> they just monitor carefully the renal function.

> Somebody can give me proof that fish oil is really efficient for

> that ? Never heard about it, since in France they never use it for

> kidney function.

> And what are ACE inhibator ? I can deduce that they inhibe something,

> but what ? I haven't done enough English at school to understand well

> the medical vocabulary. And what are their mecanism ?

> What is Prednisone ? What effect its has ?

Your antibodies are immunoglobulins. There are 5 classes (IgA, IgD, IgE,

IgM, IgG) each with a certain function. There are alco subclasses of each

and IgA has two...IgA1 and IgA2. IgA protects against infections of the

mucous membranes of the mouth, airways and digestive tract. Immunoglobulins

are glycoroteins and the initiating cause of IgA Nephropathy is an aberrant

form of IgA1 with a defective sugar attachment. The defective IgA binds to

IgG on the mesangium. The mesangium is a thin layer of cells that helps

support the capillaries of the renal glomerulus. The IgA1+IgG stimulates

the complement cascade that results in the MAC (membrane attack complex)

that damages the mesangium. The injured kidney releases an enzyme called

renin which converts a protein secreted by the liver (angiotensinogen) into

angiotensin I. Angiotensin I is then " snipped shorter " by an enzyme to

produce angiotensin II which is responsible for elevating the blood

pressure. An ACE inhibitor is a molecule that prevents the Angiotensin

Converting Enzyme (ACE) from " snipping " Angiotensin I..hence no angiotensin

II and the BP drops. Otherwise there can be a vicious circle of more kidney

damage due to high blood pressure....more renin..etc. ACE inhibitors

therefore slow down kidney damage and stabilize blood pressure. Fish oil

contains two essential fatty acids (EPA and DHA) that MAY help preserve

tissue integrity...but the jury is still out. I, for one, think fish oil is

useful. ACE inhibitors are essential and I hope those French doctors are

also monitoring hypertension.

Jack

[Guest guest]

Thanks Rita.

You know when you learn a foreign language, it's not always easy to

understand medical vocabulary, but since that 90 % of it comes from

Greek, it helps a lot.

I told only that I haven't done enough English to understand

everything about medical vocabulary.

Thanks a lot and e-mail me when you want.

[Guest guest]

Thanks Rita.

You know when you learn a foreign language, it's not always easy to

understand medical vocabulary, but since that 90 % of it comes from

Greek, it helps a lot.

I told only that I haven't done enough English to understand

everything about medical vocabulary.

Thanks a lot and e-mail me when you want.

[Guest guest]

Thanks Rita.

You know when you learn a foreign language, it's not always easy to

understand medical vocabulary, but since that 90 % of it comes from

Greek, it helps a lot.

I told only that I haven't done enough English to understand

everything about medical vocabulary.

Thanks a lot and e-mail me when you want.