Guest guest Posted October 9, 2002 Report Share Posted October 9, 2002 Cheryl, Thank you for your message. It gave me a lot of hope and I wish you luck with your ultrasound and ttc. Roxie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 9, 2002 Report Share Posted October 9, 2002 Cheryl, Thank you for your message. It gave me a lot of hope and I wish you luck with your ultrasound and ttc. Roxie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 9, 2002 Report Share Posted October 9, 2002 Cheryl, Thank you for your message. It gave me a lot of hope and I wish you luck with your ultrasound and ttc. Roxie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 9, 2002 Report Share Posted October 9, 2002 Cheryl, Good Luck for tomorrow. Lesia Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 10, 2002 Report Share Posted October 10, 2002 Cheryl P, Thanks for updating us. Yes you are right. Your update is so relevant to members who are wanting to have that second AS baby. But it is also helpful for us to understand more things about ashermans. My theory is that your RE saying that the uterus gets back to "normal" means that the scarring is more or less completely "broken" up and removed because the uterus has stretched. The endometrium lining would be another theory to look into because it would involve the thickness of the lining rather than anything to do with the scarring. Keep updating us. Poly p.s - Can't believe that your baby is already 11 1/2 years old!!!!!!!! Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 10, 2002 Report Share Posted October 10, 2002 Cheryl P, Thanks for updating us. Yes you are right. Your update is so relevant to members who are wanting to have that second AS baby. But it is also helpful for us to understand more things about ashermans. My theory is that your RE saying that the uterus gets back to "normal" means that the scarring is more or less completely "broken" up and removed because the uterus has stretched. The endometrium lining would be another theory to look into because it would involve the thickness of the lining rather than anything to do with the scarring. Keep updating us. Poly p.s - Can't believe that your baby is already 11 1/2 years old!!!!!!!! Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 10, 2002 Report Share Posted October 10, 2002 Cheryl P, Thanks for updating us. Yes you are right. Your update is so relevant to members who are wanting to have that second AS baby. But it is also helpful for us to understand more things about ashermans. My theory is that your RE saying that the uterus gets back to "normal" means that the scarring is more or less completely "broken" up and removed because the uterus has stretched. The endometrium lining would be another theory to look into because it would involve the thickness of the lining rather than anything to do with the scarring. Keep updating us. Poly p.s - Can't believe that your baby is already 11 1/2 years old!!!!!!!! Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 10, 2002 Report Share Posted October 10, 2002 My measurement after the 4th Sx...w/o hormones was 4mm. I was on estradiol(I believe the dosage was 2.5mg 2x/day). Another time I was on estinyl(.02mg 2x/day). The dosage is different for each because they all get absorbed by the body differently. My shots were 2 amps. of Gonal-F/day for about 12 days and then a shot of HCG to trigger ovulation. My lining was 6.5mm when I got pg. That was in the thickest spot they could find...so most of my uterus was thinner. I ovulated 5 eggs, so that one found the healthiest spot. And that is another reason for injectibles; not just to thicken the lining, but to improve the overall chances per cycle of getting pg by producing more eggs. Oh....I also took baby aspirin after my surgeries in addition with the hormones and injectibles. Try not to worry too much(hard, I know). My lining never thickened after the surgeries, until I started injectibles. Then it did enough to get pg.....and now I have a beautiful 11 1/2 month old. I'll update with my lining measurement tomorrow. cheryl ://faith.yahoo.com Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 10, 2002 Report Share Posted October 10, 2002 My measurement after the 4th Sx...w/o hormones was 4mm. I was on estradiol(I believe the dosage was 2.5mg 2x/day). Another time I was on estinyl(.02mg 2x/day). The dosage is different for each because they all get absorbed by the body differently. My shots were 2 amps. of Gonal-F/day for about 12 days and then a shot of HCG to trigger ovulation. My lining was 6.5mm when I got pg. That was in the thickest spot they could find...so most of my uterus was thinner. I ovulated 5 eggs, so that one found the healthiest spot. And that is another reason for injectibles; not just to thicken the lining, but to improve the overall chances per cycle of getting pg by producing more eggs. Oh....I also took baby aspirin after my surgeries in addition with the hormones and injectibles. Try not to worry too much(hard, I know). My lining never thickened after the surgeries, until I started injectibles. Then it did enough to get pg.....and now I have a beautiful 11 1/2 month old. I'll update with my lining measurement tomorrow. cheryl ://faith.yahoo.com Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 10, 2002 Report Share Posted October 10, 2002 My measurement after the 4th Sx...w/o hormones was 4mm. I was on estradiol(I believe the dosage was 2.5mg 2x/day). Another time I was on estinyl(.02mg 2x/day). The dosage is different for each because they all get absorbed by the body differently. My shots were 2 amps. of Gonal-F/day for about 12 days and then a shot of HCG to trigger ovulation. My lining was 6.5mm when I got pg. That was in the thickest spot they could find...so most of my uterus was thinner. I ovulated 5 eggs, so that one found the healthiest spot. And that is another reason for injectibles; not just to thicken the lining, but to improve the overall chances per cycle of getting pg by producing more eggs. Oh....I also took baby aspirin after my surgeries in addition with the hormones and injectibles. Try not to worry too much(hard, I know). My lining never thickened after the surgeries, until I started injectibles. Then it did enough to get pg.....and now I have a beautiful 11 1/2 month old. I'll update with my lining measurement tomorrow. cheryl ://faith.yahoo.com Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 10, 2002 Report Share Posted October 10, 2002 CORRECTION POLY.....thank god I havent been a member that long, but Abbie is 11 1/2 MONTHS old!!! Hope your family is doing great!! > p.s - Can't believe that your baby is already 11 1/2 years old!!!!!!!! Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 10, 2002 Report Share Posted October 10, 2002 CORRECTION POLY.....thank god I havent been a member that long, but Abbie is 11 1/2 MONTHS old!!! Hope your family is doing great!! > p.s - Can't believe that your baby is already 11 1/2 years old!!!!!!!! Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 11, 2002 Report Share Posted October 11, 2002 Cheryl, Whoops!!! Yes, you are right. Sorry. I have a terrible cold at the moment and you can see what it is doing to me!! Poly Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 11, 2002 Report Share Posted October 11, 2002 Cheryl: You mention that your lining didn't thicken after your surgeries until you took injectibles. Does that mean you did not get a period? I am currently faced with a similar situation, and am trying to decide if I have a chance to get pregnant or if I should seek alternatives. I've had two surgeries, and have not had a period. Right now, I'm on my third round of hormones, Estrodial, 4mg each day for two weeks, the 6 mg each day for two weeks, then withdrawal (using some drug other than Provera). Do you think if this doesn't work that I could try injectibles could as the last resort? Also, what dosage of baby aspirin did you take, and how often did you take it? I've been trying that recently as well. Thanks for any insight you may have! Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 11, 2002 Report Share Posted October 11, 2002 Cheryl: You mention that your lining didn't thicken after your surgeries until you took injectibles. Does that mean you did not get a period? I am currently faced with a similar situation, and am trying to decide if I have a chance to get pregnant or if I should seek alternatives. I've had two surgeries, and have not had a period. Right now, I'm on my third round of hormones, Estrodial, 4mg each day for two weeks, the 6 mg each day for two weeks, then withdrawal (using some drug other than Provera). Do you think if this doesn't work that I could try injectibles could as the last resort? Also, what dosage of baby aspirin did you take, and how often did you take it? I've been trying that recently as well. Thanks for any insight you may have! Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 12, 2002 Report Share Posted October 12, 2002 As far as I know, all the injectable gonadotropin medications do for the endometrium is increase the estrogen level by however many follicles they stimulate. Basically, pretty much all those medications do (when they work) is stimulate formation of lots of eggs. If you aren't getting any endometrial response to increased estrogen levels from oral or topical estrogen, I don't know that you would get any response to the increased estrogen levels with injectable medications. I think they can get pretty high estrogen levels with oral/topical estrogen and as far as I know estrogen from oral or topical estrogen does reach the endometrium (however, I heard from one of the fellows training in the fertility clinic where I'm treated, that progesterone suppositories deliver greater amounts of progesterone to the uterus than oral progesterone). The injectable medications very expensive and uncomfortable and not altogether safe (risk of overstimulation of the ovary). You should ask your doctor, but it seems to me that unless there is good reason to believe there would be some specific added benefit from injectable gonadotropins (e.g., Gonal F), you would be taking on unnecessary risk and expense that wouldn't do you a bit of good. What medication will you be using to induce withdrawal bleeding this month? Helen Marie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 12, 2002 Report Share Posted October 12, 2002 As far as I know, all the injectable gonadotropin medications do for the endometrium is increase the estrogen level by however many follicles they stimulate. Basically, pretty much all those medications do (when they work) is stimulate formation of lots of eggs. If you aren't getting any endometrial response to increased estrogen levels from oral or topical estrogen, I don't know that you would get any response to the increased estrogen levels with injectable medications. I think they can get pretty high estrogen levels with oral/topical estrogen and as far as I know estrogen from oral or topical estrogen does reach the endometrium (however, I heard from one of the fellows training in the fertility clinic where I'm treated, that progesterone suppositories deliver greater amounts of progesterone to the uterus than oral progesterone). The injectable medications very expensive and uncomfortable and not altogether safe (risk of overstimulation of the ovary). You should ask your doctor, but it seems to me that unless there is good reason to believe there would be some specific added benefit from injectable gonadotropins (e.g., Gonal F), you would be taking on unnecessary risk and expense that wouldn't do you a bit of good. What medication will you be using to induce withdrawal bleeding this month? Helen Marie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 13, 2002 Report Share Posted October 13, 2002 Helen Marie: Thank you for your response. It was very helpful. Have you heard of anyone ever not responding to oral estrogen? Do you know of anyone that has just never been able to develop the endometrium again? I am not certain of what's going to be used to withdraw me, but it sounds like the doctor will use something other than Provera this time, as this last attempt failed again. Thanks again. B Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 13, 2002 Report Share Posted October 13, 2002 Helen Marie: Thank you for your response. It was very helpful. Have you heard of anyone ever not responding to oral estrogen? Do you know of anyone that has just never been able to develop the endometrium again? I am not certain of what's going to be used to withdraw me, but it sounds like the doctor will use something other than Provera this time, as this last attempt failed again. Thanks again. B Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 13, 2002 Report Share Posted October 13, 2002 I don't understand your message to me. I get my period so I don't need meds. for a w/drawal bleed. The benefits of the injectibles are getting pg!!! Which worked the 2nd cycle that I was on them. I had 7 mature follicles---all producing estrogen. And I also took oral and vaginal estrogen. Shots increase your chance of conceiving by increasing estrogen ie. number of eggs ovulated/cycle. cheryl ps. the RE follows you closely by doing US every other day to avoid hyperstim. > What medication will you be using to induce withdrawal bleeding this > month? > > Helen Marie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 13, 2002 Report Share Posted October 13, 2002 I don't understand your message to me. I get my period so I don't need meds. for a w/drawal bleed. The benefits of the injectibles are getting pg!!! Which worked the 2nd cycle that I was on them. I had 7 mature follicles---all producing estrogen. And I also took oral and vaginal estrogen. Shots increase your chance of conceiving by increasing estrogen ie. number of eggs ovulated/cycle. cheryl ps. the RE follows you closely by doing US every other day to avoid hyperstim. > What medication will you be using to induce withdrawal bleeding this > month? > > Helen Marie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 13, 2002 Report Share Posted October 13, 2002 I didn't respond to Premarin too well. But I did with estradiol and vaginal estrace. This was also minimal(2.5mm). But it was enough to get pg. cheryl Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 13, 2002 Report Share Posted October 13, 2002 I didn't respond to Premarin too well. But I did with estradiol and vaginal estrace. This was also minimal(2.5mm). But it was enough to get pg. cheryl Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 14, 2002 Report Share Posted October 14, 2002 I don't respond very much to estrogen. My endometrium grows by about 2 mm, but I do get a period. I can see endometrium grow on ultrasound on 50-75% of my uterus, but there is no growth in some areas. My doctors, at various points along the way, told me that I might not be able to regrow any endometrium or stay open. I think the doctor is still concerned that I could get recurrent adhesions and close down again. They do endometrial ablation deliberately for women who are having a lot of bleeding problems (e.g., around menopause) and 60% of them never bleed again (despite continued ovulation). So, it is possible to lose all your endometrium and not bleed at all in response to estrogen. As I understand it, if you lose the lining all the way down to the muscle below, it doesn't regrow normally. Just like someone with a third degree burn will not regrow hair and sweat glands. Even though they grow a scar to cover the wound, it is not normal skin. But, I think the first is to make sure whether or not your uterus is open. Have you had a HSG showing it is open? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 14, 2002 Report Share Posted October 14, 2002 I don't respond very much to estrogen. My endometrium grows by about 2 mm, but I do get a period. I can see endometrium grow on ultrasound on 50-75% of my uterus, but there is no growth in some areas. My doctors, at various points along the way, told me that I might not be able to regrow any endometrium or stay open. I think the doctor is still concerned that I could get recurrent adhesions and close down again. They do endometrial ablation deliberately for women who are having a lot of bleeding problems (e.g., around menopause) and 60% of them never bleed again (despite continued ovulation). So, it is possible to lose all your endometrium and not bleed at all in response to estrogen. As I understand it, if you lose the lining all the way down to the muscle below, it doesn't regrow normally. Just like someone with a third degree burn will not regrow hair and sweat glands. Even though they grow a scar to cover the wound, it is not normal skin. But, I think the first is to make sure whether or not your uterus is open. Have you had a HSG showing it is open? Quote Link to comment Share on other sites More sharing options...
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