Re: STUDY - Pomegranate juice

[Guest guest]

Barb,

How do you possibly find the time to know so much. I am always amazed. A translation would still be in order though and I know that there is one other study. We've been drinking the stuff and will be soon. It tastes like a better version of cranberry juice and it's a lot easier to consume than an actual pomegrenate.

There's one other study that I know of.

Joan

STUDY - Pomegranate juice

Nitric Oxide. 2006 Jan 11; [Epub ahead of print]

Pomegranate juice reduces oxidized low-density lipoprotein downregulation of endothelial nitric oxide synthase in human coronary endothelial cells.de Nigris F, -Ignarro S, Botti C, Sica V, Ignarro LJ, Napoli C.Department of General Pathology and Excellence Research Center on Cardiovascular Disease, University of Naples, Italy.We examined the hypothesis that pomegranate juice (PJ) can revert the potent downregulation of the expression of endothelial nitric-oxide synthase (NOSIII) induced by oxidized low-density liporotein (oxLDL) in human coronary endothelial cells. Western blot and Northern blot analyses showed a significant decrease of NOSIII expression after a 24-h treatment with oxLDL. Accordingly, we observed a significant dose-dependent reduction in nitric oxide bioactivity represented by both basal and bradykinin-stimulated cellular cGMP accumulation. These phenomena were corrected significantly by the concomitant treatment with PJ. Our data suggest that PJ can exert beneficial effects on the evolution of clinical vascular complications, coronary heart disease, and atherogenesis in humans by enhancing the NOSIII bioactivity.PMID: 16413211 [PubMed - as supplied by publisher]

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