ACE Inhibitors may be better than Calcium Channel Blockers

[Guest guest]

I found a new study (July 7, 2004) on PubMed today that seems to say

that for fibbers with high blood pressure get better results (more

reduction in fib episodes)when their blood pressure is treated with

ACE inhibitors than with calcium channel blockers. Here is a tiny URL

link: http://tinyurl.com/2eefz

H, Charlotte NC

60M, flecainide 150mg x 2, aspirin 325mg

[Guest guest]

> I found a new study (July 7, 2004) on PubMed today that seems to say

> that for fibbers with high blood pressure get better results (more

> reduction in fib episodes)when their blood pressure is treated with

> ACE inhibitors than with calcium channel blockers. Here is a tiny URL

> link: http://tinyurl.com/2eefz

> H, Charlotte NC

> 60M, flecainide 150mg x 2, aspirin 325mg

- I take both. Cardizem for rate control if needed and blood

pressure and enalapril (generic vasotec) for blood pressure. The

combination seems to be doing the job better for me than either has by

itself.

Ed in VA

[Guest guest]

> I found a new study (July 7, 2004) on PubMed today that seems to

say

> that for fibbers with high blood pressure get better results (more

> reduction in fib episodes)when their blood pressure is treated

with

> ACE inhibitors than with calcium channel blockers. Here is a tiny

URL

> link: http://tinyurl.com/2eefz

> H, Charlotte NC

> 60M, flecainide 150mg x 2, aspirin 325mg

Hi ,

I was on quinapril (an Ace inhibitor) for high blood pressure and I

ended up in hospital for nearly three weeks with AFIB. I may be the

exception, but if I got a better result re AFIB being on an ACE

Inhibitor - I can't even imagine what being on a Calcium Channel

blocker would have been like.

Germaine

Canada

propafenone, atenolol, warfarin

[Guest guest]

> From: sinusrhythm58

> Date: 7/8/04, 1:57 PM -0400

>

> I found a new study (July 7, 2004) on PubMed today that seems to say

> that for fibbers with high blood pressure get better results (more

> reduction in fib episodes)when their blood pressure is treated with

> ACE inhibitors than with calcium channel blockers. Here is a tiny URL

> link:

(I tried to upload the full article but it didn't work.

If someone is interested I will send it directly.)

Journal of the American College of Cardiology

Volume 44, Issue 1 , 7 July 2004, Pages 159-164

" Angiotensin-Converting Enzyme Inhibition in

Hypertensive Patients Is Associated With a

Reduction in the Occurrence of Atrial Fibrillation "

This study compared ACEIs with CCBs as to their effect

on A-fib, and the investigators concluded,

" Angiotensin-converting enzyme inhibition was associated

with a reduced incidence of AF for patients with

hypertension in a managed care setting. "

" The absolute incidence of AF in this cohort of

hypertensive patients was 10.6% versus 13.0% at six

years and 19.4% versus 22.1% at seven years in the

ACEI and CCB groups, respectively. "

Of the selected patients it is said, " Clinical and

demographic characteristics were nearly identical in

both groups (Table 1), " yet 19.6% of the CCB group

also received BBs while only 15.5% of the ACEI group

received BBs. Because BBs can reduce the frequency of

A-fibs the higher percentage of patients in the CCB

group receiving BBs must have had a positive effect

on the CCB group, and without this distortion the

results would have been even more in favor of the ACEI

group.

My doc believes ACEIs are benificial.

http://tinyurl.com/2jusg

> H, Charlotte NC

> 60M, flecainide 150mg x 2, aspirin 325mg

, you obviously have no problem with the flecainide,

but as a precaution, did your doc discuss the use of a

negative chronotrop? http://tinyurl.com/yr8xy

[Guest guest]

(snip)

> , you obviously have no problem with the flecainide,

> but as a precaution, did your doc discuss the use of a

> negative chronotrop? http://tinyurl.com/yr8xy

Fred:

No. I am an active exerciser, with a resting heart rate in the 50's.

The only times they have given me any rate control med (Toprol) was

during the course of a conversion from an afib episode.

.

[Guest guest]

(snip)

> , you obviously have no problem with the flecainide,

> but as a precaution, did your doc discuss the use of a

> negative chronotrop? http://tinyurl.com/yr8xy

Fred:

No. I am an active exerciser, with a resting heart rate in the 50's.

The only times they have given me any rate control med (Toprol) was

during the course of a conversion from an afib episode.

.

[Guest guest]

Sending it again - 7/12/04, 8:38 PM -0400 mailing

didn't make it to the list.

-----------------------------------

> From: fredmcc@...

> Date: 7/11/04, 1:51 AM -0400

>

snip

> (I tried to upload the full article but it didn't work.

> If someone is interested I will send it directly.)

>

> Journal of the American College of Cardiology

> Volume 44, Issue 1 , 7 July 2004, Pages 159-164

>

> " Angiotensin-Converting Enzyme Inhibition in

> Hypertensive Patients Is Associated With a

> Reduction in the Occurrence of Atrial Fibrillation "

I tried the upload again and this time it worked:

http://tinyurl.com/36dnm

j_am_college_v44_1_p159.pdf

ACEIs reduce occurrence of A-fib

[Guest guest]

Sending it again - 7/12/04, 8:38 PM -0400 mailing

didn't make it to the list.

-----------------------------------

> From: fredmcc@...

> Date: 7/11/04, 1:51 AM -0400

>

snip

> (I tried to upload the full article but it didn't work.

> If someone is interested I will send it directly.)

>

> Journal of the American College of Cardiology

> Volume 44, Issue 1 , 7 July 2004, Pages 159-164

>

> " Angiotensin-Converting Enzyme Inhibition in

> Hypertensive Patients Is Associated With a

> Reduction in the Occurrence of Atrial Fibrillation "

I tried the upload again and this time it worked:

http://tinyurl.com/36dnm

j_am_college_v44_1_p159.pdf

ACEIs reduce occurrence of A-fib