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Re: THE MOSS REPORTS

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Unfortunately,this is not new news-or unique to Erbitux.If you read

the actual clinical trial result data for any chemo drug you will

find that the " significant improvements " in progression time or over-

all survival time are often only a few weeks or months. BUT,each of

these new drugs have and will work more effectively for some

individuals and you just never know, you or your family member may be

one of the lucky ones.You have to decide if the risk is worth the

possible outcome. Also,if the quality of life is improved,even

without extension, it is well worth it.And, the chances of being here

to try something else that may be better or may work for you improve

with every month.It's what allows all of us to have Hope.

You're right,the Moss reports are not a profit gimmick,they just make

data available in an easier format.You can obtain the same info for

free by reading the clinical trial results on the cancer.gov or

national cancer intitute websites(the sites are linked)

Keep your chin up!!!

> Interesting about Erbitux's weaknesses. Is Avastin going to be

> better? Why go through the hell of side effects for an extran month

> and a half? Doesn't look like Dr. Moss has a commercial agenda

other

> than his own books. Hopefuly oncologists will shake out a

effective

> use of Erbitux as they administer it to patients.

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Unfortunately,this is not new news-or unique to Erbitux.If you read

the actual clinical trial result data for any chemo drug you will

find that the " significant improvements " in progression time or over-

all survival time are often only a few weeks or months. BUT,each of

these new drugs have and will work more effectively for some

individuals and you just never know, you or your family member may be

one of the lucky ones.You have to decide if the risk is worth the

possible outcome. Also,if the quality of life is improved,even

without extension, it is well worth it.And, the chances of being here

to try something else that may be better or may work for you improve

with every month.It's what allows all of us to have Hope.

You're right,the Moss reports are not a profit gimmick,they just make

data available in an easier format.You can obtain the same info for

free by reading the clinical trial results on the cancer.gov or

national cancer intitute websites(the sites are linked)

Keep your chin up!!!

> Interesting about Erbitux's weaknesses. Is Avastin going to be

> better? Why go through the hell of side effects for an extran month

> and a half? Doesn't look like Dr. Moss has a commercial agenda

other

> than his own books. Hopefuly oncologists will shake out a

effective

> use of Erbitux as they administer it to patients.

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An example of material available to the general public.Today's newspaper

reported that the FDA had approved AVASTIN as a treatment for colorectal cancer.

It is

not a cure,it helps prolong life,as much as five months to three years in

some in-

stances.We were part of an initial clinical trial that in the beginning

yielded tremendous results. Livert mets all but disappeared. Then some 6 months

later they

reappeared,larger and more widespread. Still the initial results,combined

with chemo-

therapy were indeed positive. You,and your oncologist have to decide whether

the

risks outweigh the benefits or whether,it might be the only option available.

It is

exactly as printed,not a cure,results vary by indivuals,stage or progression

of the

diesase and other medical conditions existing at the same time. Sometimes

those

conducting the studies get carried away but then that tempers as time and

nature

define the inevitable. I truly believe that someday,somewhere,somehow there

will be

a cure. Whether it will be bio-engineered,the result of automated and

computerized

technology,or the culmination of may efforts on several different fronts.

There will

always be controversy,people will disagree as to why some results occurred

and

why they were only temporary. research is not an exact science and like

snowflakes

each of us has out own genetic phisiology. Just some thoughts from ' been

there,done that.'

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Nick- Thank you for being part of the clinical trial.

I hear that only a small number of people are ever evaluated for

clinical trials, even though especially the Phase 2 trials are the

only way to get access to very new promising treatments, in addition

to the routine " gold standard " treatment.

Although I have unexpectedly been doing well on just oxaliplatin/

Xeloda, I was not eligble for the clinical trials for EGF or VEGF

inhibitors when my tumor was rapidly progressing 9 mth ago and my

oncologist was pessimistic that I would respond again to

oxaliplatin. My oncologist (who participated in the Avastin trials)

has been anxious to have access to it again for patients like me who

may need it in the near future. Your participation and sucess with

it has opened some new options for others of us in this fight.

Thank you,

Kris

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