Guest guest Posted February 23, 2004 Report Share Posted February 23, 2004 Has anyone used Amiodarone to come out of Afib...and if so, was it successful? Answer: Amio. has a very long half life therefore I don't believe that it could be used to stop AF. My wife has been on Amio. approx. 15 ys, thank God, with great success but Amio. has to reach a certain level in the system in order to be effective. I'll be glad to hear from you, Ervin Amiodarone Greetings from Southern California on Monday morning, Has anyone used Amiodarone to come out of Afib...and if so, was it successful? In addition, would anyone with info re this drug/medicine send it to me louisecalabrese@... Thank you! Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 23, 2004 Report Share Posted February 23, 2004 > Has anyone used Amiodarone to come out of Afib...and if so, was it > successful? > Answer: Amio. has a very long half life therefore I don't believe that it > could be used to stop AF. Ervin, could you expand on this comment please. I'm curious to know why you think its large half life would prevent this. The half life is related to how quickly amiodarone leaves the system. My understanding is whilst it does take long time for amiodarone to reach a steady state for long term use a single high dosage of amiodarone achieves peak plasma levels within 3—7 hours. If one is to be given it long term it is often given first at a high dosage to load the system and then the dosage is reduced. A one off high dosage is also used in ER situations to try to terminate AF. (it was tried twice on me in the ER) Many thanks -- D Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 24, 2004 Report Share Posted February 24, 2004 > From: Driscoll > Date: 2/23/04, 5:21 PM -0500 > > > > Has anyone used Amiodarone to come out of Afib... > > and if so, was it successful? > > Answer: Amio. has a very long half life therefore > > I don't believe that it could be used to stop AF. > > Ervin, could you expand on this comment please. I'm > curious to know why you think its large half life > would prevent this. This argument, that amiodarone will not convert BECAUSE it has a long elimination half life, is rubbish - there is no correlation brtween the half life and the efficacy of a pharmacological cardioversion agent. Actually, amiodarone is one of the most effective ones. See: http://www.fpnotebook.com/CV7.htm Quote Link to comment Share on other sites More sharing options...
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