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Re: IGA Nephropathy and Gout

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Hy C.J.

Gout is caused by increased uric acid. In IgA and CRF

mild increase in uric acid can occur and in most of

the cases it does not cause symptoms. I think yr Uric

acid level has increased much more.

--- DaboCJ@... wrote:

>

> , Pierre, and others...Hello!!

>

> My name is C.J. I have been a subscriber to

> this website for several

> months. This is my first email. I was wondering

> whether anyone knows if there

> is direct correllation between IGAN and Gout?

>

> I was diagnosed with IGAN presumptively in 1987

> and this was confirmed by

> biopsy in 1995. I have been very fortunate over the

> years with respect to

> IGAN. However, over the past two years I have had

> recurring Gout attacks. 7 in

> the last two years. Most recently this past summer

> where I had three acute

> attacks back to back, lasting from the end of Jun to

> the end of August.

>

> Any information on whether there is a direct

> correllation between the

> IGAN and Gout would be much appreciated.

>

> Thanks,

>

> C.J.

>

>

> [Non-text portions of this message have been

> removed]

>

>

>

>

>

________________________________________________________________________

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Hi C.J.

A very warm welcome to our group! I am glad you posted. We always love

welcoming new members. You must be doing well with your IgAN to be almost 20

years into it and still be able to call yourself fortunate. I hope that means

your levels are good and you are stable.

With chronic renal insufficiency, uric acid can built up and some of our

members have struggled with gout. There is a medication which I can't recall

right now that you can take to prevent attacks. Hopefully another member will

write in with the name of it. Perhaps you can ask your Nephrologist about

taking

it proactively.

Welcome again.

In a message dated 10/4/2004 5:51:55 PM Pacific Daylight Time, DaboCJ@...

writes:

>

> , Pierre, and others...Hello!!

>

> My name is C.J. I have been a subscriber to this website for several

> months. This is my first email. I was wondering whether anyone knows if

> there

> is direct correllation between IGAN and Gout?

>

> I was diagnosed with IGAN presumptively in 1987 and this was confirmed by

> biopsy in 1995. I have been very fortunate over the years with respect to

> IGAN. However, over the past two years I have had recurring Gout attacks.

> 7 in

> the last two years. Most recently this past summer where I had three acute

> attacks back to back, lasting from the end of Jun to the end of August.

>

> Any information on whether there is a direct correllation between the

> IGAN and Gout would be much appreciated.

>

> Thanks,

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Thanks and ! Allopurinol was just the med I was thinking of but

could not quite remember.

In a message dated 10/5/2004 9:31:07 AM Pacific Daylight Time,

jpman@... writes:

> C.J.,

>

> I too have had bouts with gout in the past.

>

> My understanding is that I have two big strikes that make me more susceptive

> to gout:

>

> 1. Overweight

> 2. IGA Nephropathy (the lack of filtration causing uric acid build-ups, as

> I was told by my Neph)

>

> I was given allopurinol to take daily. It has worked really well. I was

> also given Colchicine as an " emergency pill " when it flares up. I keep up

> with my daily dose of allopurinol and I have not had a gout flare-up in

> about 2 years.

>

> I hope this helps.

>

> Remember, your thoughts are Golden.

>

> Regards,

> Hodges

> San Marcos, Texas

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C.J.,

I too have had bouts with gout in the past.

My understanding is that I have two big strikes that make me more susceptive

to gout:

1. Overweight

2. IGA Nephropathy (the lack of filtration causing uric acid build-ups, as

I was told by my Neph)

I was given allopurinol to take daily. It has worked really well. I was

also given Colchicine as an " emergency pill " when it flares up. I keep up

with my daily dose of allopurinol and I have not had a gout flare-up in

about 2 years.

I hope this helps.

Remember, your thoughts are Golden.

Regards,

Hodges

San Marcos, Texas

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To kind of sum up what others have already posted, there is nothing specific

about IgA nephropathy that causes gout. However, some aspects of the chronic

renal insufficiency that eventually develops from the IgA nephropathy can

increase the chances of gout in some people who may already have some

predisposition to it (tendency to for uric acid to form crystals) (some of

these may have never had gout previously). To my knowledge, it doesn't make

any difference what kidney disease caused the chronic renal insufficiency.

Luckily for those who have it, gout is usually easily treated these days.

Pierre

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The only other thing I can add is that you should get some

colchicine and keep it with you at all times so at the very first

inkling of a gout attack, start taking it. I used to take one every

two hours until I couldn't stand the diarrhea when I felt it flare

up. The diarrhea was better than the gout attack by far. If I

didn't take it right during the initial symptoms, then it

would be almost impossible to stop and I would have to let it run

its course, colchicine or no colchicine.

The other thing is to avoid alchohol. That will trigger an flare up

in most people. Allopurinnol, which others have mentioned, helps as

well.

Note; I have had no attacks since my TX.

>

> , Pierre, and others...Hello!!

>

> My name is C.J. I have been a subscriber to this website for

several

> months. This is my first email. I was wondering whether anyone

knows if there

> is direct correllation between IGAN and Gout?

>

> I was diagnosed with IGAN presumptively in 1987 and this was

confirmed by

> biopsy in 1995. I have been very fortunate over the years with

respect to

> IGAN. However, over the past two years I have had recurring Gout

attacks. 7 in

> the last two years. Most recently this past summer where I had

three acute

> attacks back to back, lasting from the end of Jun to the end of

August.

>

> Any information on whether there is a direct correllation

between the

> IGAN and Gout would be much appreciated.

>

> Thanks,

>

> C.J.

>

>

>

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CJ, and others with gout, Very quick note here just to put my 2 cents in. Yes,

Colchicine is a " safe " drug for kidneys, but the dose must be correlated to the

degree of renal function. When GFR is decreased the dose of colchicine must be

decreased as well. The dose listed below (0.6 mg every 2 hours until pain is

relieved, or diarrhea or nausea ensues) is for a perfectly normal GFR. The

usual dose of my patients with impaired renal function is 0.6 every day, until

pain is relieved, nausea/vomiting or diarrhea. (But again the dose will be

based on GFR, so may vary from patient to patient, or even vary for 1 patient

that has deteriorating renal function. Allopurinol is the drug that is used

" long term " to decrease uric acid (and absolutely not used for an acute attack

of gout) must also be dosed " special " for renal insufficiency patients.

(usually 100 mg per day, not 300mg per day as for patients with normal renal

function). One must always check with their physician and/or

nephrologist and/or pharmacist. We all have computer programs where we put the

medication in the program and input GFR data to come out with the appropriate

dose for any particular medication. All NSAIDS are contraindicated in Ig A,

especially ones like Indocin, which we used to use all the time for patients

with gout.

Regarding your question though re: Ig A and gout, I am not aware of any

correlation to speak of. OK, back to work......Bonnie

leadpencil1 wrote:

The only other thing I can add is that you should get some

colchicine and keep it with you at all times so at the very first

inkling of a gout attack, start taking it. I used to take one every

two hours until I couldn't stand the diarrhea when I felt it flare

up. The diarrhea was better than the gout attack by far. If I

didn't take it right during the initial symptoms, then it

would be almost impossible to stop and I would have to let it run

its course, colchicine or no colchicine.

The other thing is to avoid alchohol. That will trigger an flare up

in most people. Allopurinnol, which others have mentioned, helps as

well.

Note; I have had no attacks since my TX.

>

> , Pierre, and others...Hello!!

>

> My name is C.J. I have been a subscriber to this website for

several

> months. This is my first email. I was wondering whether anyone

knows if there

> is direct correllation between IGAN and Gout?

>

> I was diagnosed with IGAN presumptively in 1987 and this was

confirmed by

> biopsy in 1995. I have been very fortunate over the years with

respect to

> IGAN. However, over the past two years I have had recurring Gout

attacks. 7 in

> the last two years. Most recently this past summer where I had

three acute

> attacks back to back, lasting from the end of Jun to the end of

August.

>

> Any information on whether there is a direct correllation

between the

> IGAN and Gout would be much appreciated.

>

> Thanks,

>

> C.J.

>

>

>

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I don't know of any studies on the relative incidence of IgAN and gout, but

I do know a number of kidney patients (including IgAN, MPGN and a FSGS

gentleman) who have gout. Just from personal observation, the incidence

seems a little skewed.

Cy

Re: Re: IGA Nephropathy and Gout

>

> CJ, and others with gout, Very quick note here just to put my 2 cents in.

Yes, Colchicine is a " safe " drug for kidneys, but the dose must be

correlated to the degree of renal function. When GFR is decreased the dose

of colchicine must be decreased as well. The dose listed below (0.6 mg

every 2 hours until pain is relieved, or diarrhea or nausea ensues) is for a

perfectly normal GFR. The usual dose of my patients with impaired renal

function is 0.6 every day, until pain is relieved, nausea/vomiting or

diarrhea. (But again the dose will be based on GFR, so may vary from

patient to patient, or even vary for 1 patient that has deteriorating renal

function. Allopurinol is the drug that is used " long term " to decrease uric

acid (and absolutely not used for an acute attack of gout) must also be

dosed " special " for renal insufficiency patients. (usually 100 mg per day,

not 300mg per day as for patients with normal renal function). One must

always check with their physician and/or

> nephrologist and/or pharmacist. We all have computer programs where we

put the medication in the program and input GFR data to come out with the

appropriate dose for any particular medication. All NSAIDS are

contraindicated in Ig A, especially ones like Indocin, which we used to use

all the time for patients with gout.

> Regarding your question though re: Ig A and gout, I am not aware of any

correlation to speak of. OK, back to work......Bonnie

>

> leadpencil1 wrote:

>

> The only other thing I can add is that you should get some

> colchicine and keep it with you at all times so at the very first

> inkling of a gout attack, start taking it. I used to take one every

> two hours until I couldn't stand the diarrhea when I felt it flare

> up. The diarrhea was better than the gout attack by far. If I

> didn't take it right during the initial symptoms, then it

> would be almost impossible to stop and I would have to let it run

> its course, colchicine or no colchicine.

>

> The other thing is to avoid alchohol. That will trigger an flare up

> in most people. Allopurinnol, which others have mentioned, helps as

> well.

>

> Note; I have had no attacks since my TX.

>

>

> >

> > , Pierre, and others...Hello!!

> >

> > My name is C.J. I have been a subscriber to this website for

> several

> > months. This is my first email. I was wondering whether anyone

> knows if there

> > is direct correllation between IGAN and Gout?

> >

> > I was diagnosed with IGAN presumptively in 1987 and this was

> confirmed by

> > biopsy in 1995. I have been very fortunate over the years with

> respect to

> > IGAN. However, over the past two years I have had recurring Gout

> attacks. 7 in

> > the last two years. Most recently this past summer where I had

> three acute

> > attacks back to back, lasting from the end of Jun to the end of

> August.

> >

> > Any information on whether there is a direct correllation

> between the

> > IGAN and Gout would be much appreciated.

> >

> > Thanks,

> >

> > C.J.

> >

> >

> >

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I was checked out for it when I had knee problems this summer, but

I'm ok. However in conversation with someone in work who suffers

badly from gout, he mentioned cherry juice, which he reckons works

really well to alleviate symptoms, this is what led to me trying

various fruit juices for the knee problems I had and then I noticed

that they help my flank pain, cherry, pineapple, apple, all work for

me.

> > >

> > > , Pierre, and others...Hello!!

> > >

> > > My name is C.J. I have been a subscriber to this website

for

> > several

> > > months. This is my first email. I was wondering whether anyone

> > knows if there

> > > is direct correllation between IGAN and Gout?

> > >

> > > I was diagnosed with IGAN presumptively in 1987 and this was

> > confirmed by

> > > biopsy in 1995. I have been very fortunate over the years with

> > respect to

> > > IGAN. However, over the past two years I have had recurring

Gout

> > attacks. 7 in

> > > the last two years. Most recently this past summer where I had

> > three acute

> > > attacks back to back, lasting from the end of Jun to the end of

> > August.

> > >

> > > Any information on whether there is a direct correllation

> > between the

> > > IGAN and Gout would be much appreciated.

> > >

> > > Thanks,

> > >

> > > C.J.

> > >

> > >

> > >

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I wonder if these juices help with your flank pain because they are a bit

acidic?

Pierre

Re: IGA Nephropathy and Gout

>

>

>

> I was checked out for it when I had knee problems this summer, but

> I'm ok. However in conversation with someone in work who suffers

> badly from gout, he mentioned cherry juice, which he reckons works

> really well to alleviate symptoms, this is what led to me trying

> various fruit juices for the knee problems I had and then I noticed

> that they help my flank pain, cherry, pineapple, apple, all work for

> me.

>

>

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not all juices work, grape juice, nothing. Can't do citrus as they

give me migraines. Mind you my wife told me they give people on

their last legs (so to speak) a big dose of vitamin C to get the

kidneys working, they don't don't know how it works, but it helps

apparently.

> I wonder if these juices help with your flank pain because they are

a bit

> acidic?

> Pierre

>

> Re: IGA Nephropathy and Gout

>

>

> >

> >

> >

> > I was checked out for it when I had knee problems this summer, but

> > I'm ok. However in conversation with someone in work who suffers

> > badly from gout, he mentioned cherry juice, which he reckons works

> > really well to alleviate symptoms, this is what led to me trying

> > various fruit juices for the knee problems I had and then I

noticed

> > that they help my flank pain, cherry, pineapple, apple, all work

for

> > me.

> >

> >

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To All that replied to my email,

Thank you for the warm welcome to the group and thank you all for the input

you provided regarding IGA and gout.

I see the nephrologist this coming Thursday. So, I will speak to him

regarding the Allopurinol, Colchisine and the juice you all talked about. I

have

been boning up on Gout on the web so I will be an informed patient.

Again Many Thanks!!

Sincerely,

C.J.

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