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Re: ARB+Beta blocker

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Hi Ram,

I am afraid that Pierre is our resident BP expert, and he is in the midst of

moving so he won't be on line for a couple of days. I don't know if Bonnie

can help out here or not.

I can tell you that for me, I have had to mix and match several different

drugs before I found a combination that worked to get my BP below 140/90.

I take Cozaar, Lopressor and Plendil, and that seems to have done the trick.

I have also tried adding a diuretic in the past. I think the doctor has to

play with the meds and see how your body responds.

Sorry to not be of more help, but this is really an area of weakness as far

as my knowledge goes for me.

Pierre should be back on line before too many days go by and I am sure he

will have a much better answer than I can give you.

I hope the new meds work to get your BP lower for you.

In a message dated 9/16/2004 7:16:42 PM Pacific Daylight Time,

job4ram2002@... writes:

> Hi

>

> I have been taking 300mg of ARB (Irbesartan)

> but I had a BP reading of 140/88 with

> a heart rate of 104 at neph's office.

>

> I have proteinuria (about 800mg/day), a lot of

> microscopic hematuria and hyaline casts.

>

> Neph has added a beta-blocker, Tenormin 25mg/day (atenolol)

> to bring down my heart rate.

>

> I request members of this egroup to kindly share

> any experience with ARB - Beta Blocker combination.

>

> Thanks

>

> Ram

>

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I'm taking 450mg/day of Avapro (ARB) first thing in the morning, as well as

900mg of Labetalol (Beta Blocker) 3 times/day (2700 mg/day). I had some

problems at first with dizziness, and from time to time I can get about 5

seconds of disequilibrium. However, my neph says that my progression has

stopped at about 35% GFR (4 years after diagnosis). My BP stays right

within a nice range (120/70) to (130/80).

I tell everyone that I know if I wasn't taking the pills -- I would probably

not even know that I had the disease.

One thing -- I'm still taking lots of other things, like diuretics,

nephrocaps, calcitriol, sodium bicarbonate, iron, and procrit. But the two

big BP medicines are the biggest part of my treatment...

Walt

_____

From: job4ram2002

Sent: Thursday, September 16, 2004 10:06 PM

To: iga-nephropathy

Subject: ARB+Beta blocker

Hi

I have been taking 300mg of ARB (Irbesartan)

but I had a BP reading of 140/88 with

a heart rate of 104 at neph's office.

I have proteinuria (about 800mg/day), a lot of

microscopic hematuria and hyaline casts.

Neph has added a beta-blocker, Tenormin 25mg/day (atenolol)

to bring down my heart rate.

I request members of this egroup to kindly share

any experience with ARB - Beta Blocker combination.

Thanks

Ram

To edit your settings for the group, go to our Yahoo Group

home page:

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To unsubcribe via email,

iga-nephropathy-unsubscribe

Visit our companion website at www.igan.ca. The site is entirely supported

by donations. If you would like to help, go to:

http://www.igan.ca/id62.htm

Thank you

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Hi Amy,

That is good you have been able to control your BP. It is vitally important

to protecting your renal function because elevated BP by itself is a risk

factor for kidney failure.

I hope this combination of BP meds continues to be successful for you!

In a message dated 9/18/2004 10:17:37 AM Pacific Daylight Time,

amyscarlton@... writes:

> Hi,

> I'm not sure about the combinations but I am also on beta blockers and ace

> inhibitors.

> I am on Altace 5 mg(ace inhibitor), Ziac 10 mg(beta blocker) and Caduet

> which is a combination of Lipitor and Norvasc. My bloodpressure was still

> elevated after my neph started me on Norvasc and then he doubled all meds. I

> think I have it under control now.

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Hi Ram, Sorry it's taken me so long to respond to your post. I was trying to

locate a post I had written for someone here on the difference between an ACE

and an ARB. I finally found it ...July 17th 3:00pm or so, Subject is Protein

levels and Ramipril. May want to read this post first then come back to this

note. (I'm trying to condense, which is so hard for me...(hehehehe). Ibesartan

is the same drug as Avapro. Tenormin = Atenolol which is a beta blocker

which,as you said, lowers your heart rate. Beta blockers decrease the influence

of the sympathetic nervous system (your fight or flight response) on the

excitability of the heart, cardiac work load, oxygen consumption and the release

of renin. In this way, beta blockers decrease heart rate, decrease blood

pressure and improve some fast heart rhythms. They (the entire class of beta

blockers) have been proven over and over to decrease morbidity and mortality in

patients with heart disease, and the potential for those

patients at a higher risk. One of the biggest things that the nephs look at

with renal disease is not exactly how long it will take you to get to end stage

renal disease, but the complications that also go along with renal disease

including hyperlipidemia, hypertension etc. As one of the local nephs I've been

working with said 2 weeks ago, " the idea of " dying " from kidney disease in the

long run is much less likely than having a cardiovascular event "

(atherosclerosis, heart attack, stroke etc). In other words if you have kidney

disease, you will much more likely develop cardiovascular problems way before

you develop ESRD (end stage renal disease). That is why the nephs and IM docs

(and NP's hehehe) work soooooooo hard on getting everyone to goal B/P of

<130/70, and decreasing the lipids. If your interested in the new guidelines

for CKD lipids for adults, go to my post 7/21/04 the link for the new guidelines

are there. Let me know if you have any problems navigating there. Hope

that helps, if not clear, just email me back and I try to explain things

another way. Bonnie

job4ram2002 wrote:

Hi

I have been taking 300mg of ARB (Irbesartan)

but I had a BP reading of 140/88 with

a heart rate of 104 at neph's office.

I have proteinuria (about 800mg/day), a lot of

microscopic hematuria and hyaline casts.

Neph has added a beta-blocker, Tenormin 25mg/day (atenolol)

to bring down my heart rate.

I request members of this egroup to kindly share

any experience with ARB - Beta Blocker combination.

Thanks

Ram

To edit your settings for the group, go to our Yahoo Group

home page:

http://groups.yahoo.com/group/iga-nephropathy/

To unsubcribe via email,

iga-nephropathy-unsubscribe

Visit our companion website at www.igan.ca. The site is entirely supported by

donations. If you would like to help, go to:

http://www.igan.ca/id62.htm

Thank you

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Hi Ram,

I don't know about ARB, but I have been taking beta blockers and they

really got my BP down well. I have also taken atenolol for many

years for an irregular heart beat and it works really well. My neph

took me off atenolol for a short period and my pulse rate went up

immediately.

Good luck and stay well!.........Gloria

> Hi

>

> I have been taking 300mg of ARB (Irbesartan)

> but I had a BP reading of 140/88 with

> a heart rate of 104 at neph's office.

>

> I have proteinuria (about 800mg/day), a lot of

> microscopic hematuria and hyaline casts.

>

> Neph has added a beta-blocker, Tenormin 25mg/day (atenolol)

> to bring down my heart rate.

>

> I request members of this egroup to kindly share

> any experience with ARB - Beta Blocker combination.

>

> Thanks

>

> Ram

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