Guest guest Posted September 13, 2000 Report Share Posted September 13, 2000 Keflex is a penecillin class drug. If you are concerned with feeding the bugs and causing a herx, I would be careful. Back up your administration of Keflex (Caphalexin) with antihystamine, to reduce the alergic reaction to the bacteria die-off, and the increased mycoplasma toxic release. Creighton rheumatic Keflex Anyone taken Keflex while on the AP? Do I have to stop tetracycline while taking it? I seem to remember someone saying awhile ago that they had a herx while on it?? I haven't taken it for years and was just wondering if anyone had recent experience with it. I went to my doctor today and said Pleeeeeeeeeease could we try another, different antibiotic for this sinus infection I can't seem to shake, so he gave me Cephalexin (Actually he wrote Keflex, but my insurance only covers the generic). It is a cephalosporin, I think. Just wondering if I should stop tetracycline while taking it, like you do with penicillin, so it will work better. And wondering if I should be hanging onto my hat and getting ready for a bumpy ride. ; ) the only thing I remember about taking it before was that awful taste in my mouth (like sucking on plastic all day) and that it once cleared up an ear infection I couldn't shake for months. Liz G To unsubscribe, email: rheumatic-unsubscribeegroups Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 14, 2000 Report Share Posted September 14, 2000 Dear Creighton, Would antihistamines help with the herx from other antibiotics, such as Biaxin, when used long term on a daily basis for the AP? Thanks, Gloria Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 14, 2000 Report Share Posted September 14, 2000 Gloria, et al, I am taking my information from the following website: http://www.folkarts.com/idef Specifically, the page on Herxheimer: http://www.folkarts.com/idef/herxheimer.htm I believe Henry Schammel's books also reference the use of antihistamines to combat Herx. Copy of IDEF page included herein: =Begin Transcript================================================================== ============================= The Jarisch-Herxheimer reaction (referred to as " Herx " often) is believed to be a reaction caused by organizisms (bacteria) dying off and releasing toxins into the body faster than the body may comfortably handle it. It was originally observed in patients with syphilis who received mercury treatment [*]. Most CFSers will have moderate to severe herx effects from antibiotics that will usually have no effects on normal healthy individuals[83% in one R.A. study, 51.4% in Lyme Disease, 89% with B. recurrentis infection]. The reason for this may be the diminished blood flow system caused by the thickening of the blood commonly found with CFS patients. Alternatively, " it seemed to occur when injured or dead bacteria released their products into blood and tissues, provoking a sudden and exaggerated inflammatory response " [*] - thus the response may be connected to the specific organism being killed off. Many non-antibiotic treatments (Hale's breathing, glutathione - whey products ) are reported to also produce a herx effect -- whether it is bacteria die off or simply toxin release, the effect is the same: misery! Readings: What is a Herxheimer Reaction? http://www.x-l.net/Lyme/HERX.html The Herxheimer Reaction History [History and current theories (technical)] http://garynull.com/Documents/Arthritis/Herxheimer_Effect.htm The New England Journal of Medicine -- August 1, 1996 -- Vol. 335, No. 5 http://www.nejm.org/content/1996/0335/0005/0347.asp http://www.cmc.net/~jadevoll/herxheimer.htm Onset Depending on illness and antibiotic: from 1-2 hrs to 10 days after antibiotics started Symptoms The most common ones include: increased joint or muscle pain headaches chills Heavy perspiration and night sweats Nausea Burning micturition Bone pain swollen glands bloating constipation or diarrhea fever (usually low grade) hypotension (low blood pressure) Itching, hives and rash (sometimes mistaken for an allergic reaction - this must be an MD's call) heart palpitations, elevated heart rate, orthostatic Tachycardia are reported on cfs_Mycoplasma/ Treatment Probenecid (Dr. Jadin [*]) Benadryl (antihistamine) Therma-Flu or equivalent Aspirin (Bromelain may increase it!) Meptazinol [*, *] Increase in blood thinning supplements Lemon/Olive Oil drink (may be done with water or Grape Juice) 2 Tbsp Lemon Juice (Organic) or 1/2 lemon rind) 1 Tbsp cold pressed Extra Virgin Olive Oil Water or juice ... stir Concord Grape Juice with flavoids (widens blood vessels) NSAIDs (non-steroidal anti-inflammatory drugs), pain medication (see ibuprofen risks..) muscle relaxers, hot baths / hot tub steam (dry or hot) sauna a saltz bath: add 1 cup salt, 1 cup soda, 1 cup epsom salts, 1 cup aloe vera, to a hot bath, remain in and keep hot for about 1-1/2 hours all the while consuming about 2 quarts of warm water. Hale's breathing Control panic attacks, anxiety and worry (they constrict the blood vessels, worsening the effect). Differentiating between a Herxheimer, a flare and an allergic reaction to the drug " Laboratory tests can help differentiate between a worsening of disease (RA flare), a Herxheimer reaction to microbial toxins, and an allergic reaction to medication. 1) WBC will elevate in a Herxheimer and lower in a flare. 2) A Herxheimer will also exhibit a coincidental elevation of SED rate, gamma globulin and total globulin, and a fall in serum albumin and hematocrit. Patients who exhibit this flare reaction accompanied by anemia, depression of serum albumin, elevated total globulin and gamma globulin are probably reflecting a more intense reaction pattern to anti-L substances than in hematologically mild cases. 3) A marked increase in eosinophils (for instance about 30%) is an indication of an allergic reaction to the drug. " From http://home2.freegates.be/nvdeynde/mycoplasma/publications/mycoplasma/treatm ent/8_bestanden/8.pdf May be freely copied (site is placed in PUBLIC DOMAIN) unless a © appears on the page. Not medical advice - always consult with your MD on any treatments or supplement use. This website is intended to be a 'Rolodex' of summaries for CFS patients and URLS for their MDs. Documents are for informational purpose only, based on web surfing, and not written by a medical professional. Issues have often been simplified for easier understanding by CFS patient (commonly having Brain Fog / 40-60 IQ point drop) and may not be 'technically accurate'. =End Transcript================================================================== =============================== Creighton Burgher Re: rheumatic Keflex Dear Creighton, Would antihistamines help with the herx from other antibiotics, such as Biaxin, when used long term on a daily basis for the AP? Thanks, Gloria Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 15, 2000 Report Share Posted September 15, 2000 Hi, Thanks for the very useful information. I usually have trouble sleeping when I take antihistamines, but when pain is bad enough, I would try it or some of the other suggestions. I ordered some flax seed oil and from what I am reading, it might work even better with the lemon juice. Can you tell me what Hale's breathing is? Gloria Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 15, 2000 Report Share Posted September 15, 2000 Make sure you are taking antihistimines only, not antihistimines combined with decongestants. Straight Benedryl should actually make you drowsy. However, Pseudophedrine (decongestant) does act as an upper. Again, a reference from the IDEF page: http://www.folkarts.com/idef/breathing.htm =Begin Transcription=============================================================== ============================= The body ability to release oxygen into the body is governed by its acid/alkaline balance. Carbon Dioxide (CO2) is an essential part of this process with too low a level of CO2 resulting in less oxygen being released. These techniques seek to increase the CO2 levels by breathing techniques or equipment so more oxygen is released. Some successes have been reported but no published studies for CFS patients. Dr. Cheney sample report on oxygen consumption of CFS patient illustrates this low oxygen consumption (see oxygen.htm) NOTE: Deep breathing reduces the CO2 content and reduces the amount of oxygen that may be released. Blood pH and Breathing A blood pH between 7.35 and 7.45 is normal http://www.acp.edu/web/genchem/thedisk/bloodbuf/zback.htm] http://www.acp.edu/web/genchem/thedisk/bloodbuf/zback2.htm http://www.nursing99.com/ce/p812a.htm IMPORTANT NOTE: (most) Asthma and (most) CFS cases appear to be caused by Mycoplasma infections. This technique affects the mycoplasma by killing them with higher oxygen levels. Poor Man's Rebreather Wearing a {painter's, organic vapor or dust mask} for several hours a day seem to be effective in raising CO2 level. Some patients have reported " herxing " if they wear it a long time each day (in theory, the CO2 increase causes more oxygen to be released and thus killing mycoplasma-like bugs [oxygen becomes an antibiotic]). It's cheap, does not require a prescription and simple to use. :-) Buteyko / Hale Breathing The purpose of these exercises is to correct long term " hidden hyperventilation " . A 'point form' description is available at " Anne and Janet's introduction to The Buteyko Method " , http://www.wt.com.au/~pkolb/a & j.htm. A " popular magazine report " , AUSTRALIAN WELLBEING, 1997, 68:86-93 http://www.buteyko.com/media/healthy_breathing.html For a good scientific study (1981) see http://www.buteyko.co.nz/buteyko/trials/frames/russia.htm , this is linked to a lot of New Zealand and Australian experiences. Another site is http://www.buteyko.com/trials.html The Control Pause (CP) This is the key monitoring component for retraining yourself to breath correctly. As a first step, you should read several description of this measurement and derive your own version. For example, if you cannot sit in a chair comfortably, use a recliner etc.. This CP is described by Hale as follows: " Sit comfortably in an upright chair close to a clock with a second hand, or hold a stopwatch. Relax and breathe in and out gently, mouth closed. Pinch your nose with your fingers, after the exhalation. Keeping your mouth closed, count how many seconds you can comfortably last before you need to inhale again. Don't push yourself too hard. The accuracy of the test depends on your stopping before you reach the threshold of discomfort. Remember: you are not holding your breath in, you are emptying your lungs and then counting. When you breathe in again, try not to take in large gulps of air, control your breathing, keep your mouth closed. Do not push your Control Pause above 60. This can only be done under the guidance of a Breath Connection Practitioner. These breathing exercises, like medication, must be administered correctly " p. 48, Breathing Free Alternative versions are available online at: Instep Asthma Free, http://www.nqnet.com/buteyko/buttest.html The Buteyko Breathing Centre http://www.buteyko.co.uk/buteyko/theory.htm Chicago Yoga News, March 1999 http://www.yogachicago.com/march99/Yoganews.html Re-Training your breathing All of the techniques are modification of the following pattern: Check pause for 1 minute (helps to settle you down) Do a Control Pause (CP) Do shallow breathing for 5 (or more) minutes.. REPEAT 2,3 take a slightly bigger breath, exhale. Try to hold extend your CP for 5 additional seconds. REPEAT 3,4 Increase to 10 additional seconds (but never over 60 seconds). This is done before each meal and at bed time (or more often if the situation permits it). A modification that Hales teaches for children is to walk while holding the exhausted breath and count the number of steps taken (ideally 120 steps). Then continue walking in a normal manner (with shallow breath) and repeat in 5-10 minutes. For people who do walk regularly, this method may be helpful. Reference: Breathing Free, Hale, Harmony Books, 1999 Oxygen tanks with rebreather etc. reports that breathing oxygen did not improve CFS, and may actually cause relapse. Oxygen using a rebreather(to increase CO2) has been prescribed by Dr.Cheney and several people are trying this. Hyper baric Breathing CFSFMExperiment have several people waiting to spend some time in hyperbaric chambers (decompression chambers) where the atmospheric pressure will be increased several fold. The theory is that this will allow more oxygen into the blood (note that this is normal air that is pressurized). Other Oxygen Therapy... This is informational only -- no reports of western physicians trying or suggesting this (one report of Eastern European physician). http://www.oxytherapy.com May be freely copied (site is placed in PUBLIC DOMAIN) unless a © appears on the page. Not medical advice - always consult with your MD on any treatments or supplement use. This website is intended to be a 'Rolodex' of summaries for CFS patients and URLS for their MDs. Documents are for informational purpose only, based on web surfing, and not written by a medical professional. Issues have often been simplified for easier understanding by CFS patient (commonly having Brain Fog / 40-60 IQ point drop) and may not be 'technically accurate'. =End Transcription=============================================================== =============================== Re: rheumatic Keflex Hi, Thanks for the very useful information. I usually have trouble sleeping when I take antihistamines, but when pain is bad enough, I would try it or some of the other suggestions. I ordered some flax seed oil and from what I am reading, it might work even better with the lemon juice. Can you tell me what Hale's breathing is? Gloria To unsubscribe, email: rheumatic-unsubscribeegroups Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 15, 2000 Report Share Posted September 15, 2000 > Make sure you are taking antihistimines only, not antihistimines combined > with decongestants. Straight Benedryl should actually make you drowsy. Unless you're like me and my family. We have reverse reaction to Benadryl and it makes me feel like my skin is crawling right off my body. My son literally climbs to the ceiling when he takes it. I could not believe it when I first heard people take it for a sleep aid, but some swear by it. I tried other decongestants for herx myself, and for me it did nothing. But it is a cheap and easy thing to try, to see if it works for you. I recommend lots of b-vitamins, a diet high in vegetables, and *lots* of water, lots of rest. Liz G Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 15, 2000 Report Share Posted September 15, 2000 Hi Everybody , I am diagonised to have reiter' syndrome per my Rheumo (or more accurately early Reiter's Syndrome ).I did a blood test (I got the results today) and the results which were of some concerns were . carbon dioxide - 23(normal 24-32) calcium,serum 10.3(normal 8.2-10.2) cholesterol 147 (normal 120-200) ANA Screen -Negative by Enzyme Immunoassay HLA-B27-Positive RF Screen , Serum-Negative CBC. WBC 14.2(Normal 3.8-10.6) Hemoglobin 13.1(Normal 13.5-17.0) Hematocrit 40.8 (Normal(41-53) Neutrophil,ABS 11.30(1.8-7.7) Monocyte0.9(Normal 0.0-0.8) SED RATE - 18(0-10) Can somebody please tell me what is wrong ?Though the doctor says that you are lucky yto be caught so early . I am on doxycycline now ,I was also given INDOCIN but I stopped it by myself since I faced stomach cramps and digestion problems . , Can you please give me some diet tips ? Thanks, Suranjan/Michigan Re: rheumatic Keflex Hi, Thanks for the very useful information. I usually have trouble sleeping when I take antihistamines, but when pain is bad enough, I would try it or some of the other suggestions. I ordered some flax seed oil and from what I am reading, it might work even better with the lemon juice. Can you tell me what Hale's breathing is? Gloria To unsubscribe, email: rheumatic-unsubscribeegroups To unsubscribe, email: rheumatic-unsubscribeegroups Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 16, 2000 Report Share Posted September 16, 2000 In a message dated 09/15/2000 4:03:56 PM Pacific Daylight Time, suranjan.banerjee@... writes: << Can somebody please tell me what is wrong ?Though the doctor says that you are lucky yto be caught so early . I am on doxycycline now >> Ah ha! welcome to thewonder filledworld of spondylatherapies. Good news is the Doxy works and many with thereediseases respondvery well to antibiotic treatment Quote Link to comment Share on other sites More sharing options...
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