Guest guest Posted February 21, 2006 Report Share Posted February 21, 2006 Yes!!!! CD itself will not prevent you from donating but weight and anemia (iron) is checked as part of the screening. I donate as often as I can (especially since the Red Cross calls my house to set up appointments for me!!!)! On Tue, 21 Feb 2006 09:52:01 -0800 (PST), Sonja Flockhart wrote > > I saw this as a response to someone getting diagnosed and it made me think; can people with CD be blood donors? Anyone know? > Sonja> > Yahoo! Mail > Use Photomail to share photos without annoying attachments. > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 21, 2006 Report Share Posted February 21, 2006 Yes you can give blood. Robin K. "He who sits on ice gets cold bottom." From: SillyYaks [mailto:SillyYaks ] On Behalf Of Sonja FlockhartSent: Tuesday, February 21, 2006 12:01 PMTo: SillyYaks Subject: blood donor I saw this as a response to someone getting diagnosed and it made me think; can people with CD be blood donors? Anyone know?Sonja Yahoo! MailUse Photomail to share photos without annoying attachments. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 21, 2006 Report Share Posted February 21, 2006 It varies by individual collection program. Some programs won't take blood from anyone with an auto-immune disorder. My local program (Rhode Island Blood Center) DOES take celiac blood. I believe in Canada that one cannot donate. But I could be wrong. I read it here: http://www.glutenfreeforum.com/index.php?showtopic=4663 and the info may have changed since this was written. And with a little more googling, I find this! http://www.celiac.mb.ca/new.html See the bottom line. > > I saw this as a response to someone getting diagnosed and it made me think; can people with CD be blood donors? Anyone know? > Sonja > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 21, 2006 Report Share Posted February 21, 2006 The only issue is recieving blood IF and it is IF you are IGA deficient from what I've read. Celiacs are 3X more likely to be IGA deficient that those in the average population (if I've got that right, could have that stat wrong, so don't quote me on it.) That was the Total Serum IGA level from your Celiac Disease panel, if you had that done. If you are IGA deficient you should probably talk to your doctor and read up on it on the internet. Rejoyce Winchester, VA > > I saw this as a response to someone getting diagnosed and it made me think; can people with CD be blood donors? Anyone know? > Sonja > > > --------------------------------- > Yahoo! Mail > Use Photomail to share photos without annoying attachments. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2006 Report Share Posted February 22, 2006 Last year I went to donate blood and a Red Cross Blood Drive and was told straight out that I could not donate blood. It had to do with CD, and even though I'm on a GFD and don't have a CD diagnosis they said no. Ironically, I don't see anything on the Red Cross' website that indicates that you would be disqualified from donating blood despite what I was told in person. Sorry for the conflicting information. Marie Arminger > > > > I saw this as a response to someone getting diagnosed and it made me > think; can people with CD be blood donors? Anyone know? > > Sonja > > > > > > --------------------------------- > > Yahoo! Mail > > Use Photomail to share photos without annoying attachments. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2006 Report Share Posted February 22, 2006 i read that celiacs are 10X more likely to be IgA deficient. one of my kids is IgA deficient and we are having to do some different blood testing to see if he has celiac like his sisters. christine Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 23, 2006 Report Share Posted February 23, 2006 My two teenagers were just worked up for celiac - both were IgA deficient. One had a positive biopsy and the other one's was negtive. Kerrichristineheiner wrote: i read that celiacs are 10X more likely to be IgA deficient. one of my kids is IgA deficient and we are having to do some different blood testing to see if he has celiac like his sisters.christine Yahoo! Mail Use Photomail to share photos without annoying attachments. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 24, 2006 Report Share Posted February 24, 2006 > > i read that celiacs are 10X more likely to be IgA deficient. one of > my kids is IgA deficient and we are having to do some different blood > testing to see if he has celiac like his sisters. > christine The IgA-less 'gene' is commonly found in the Super B8 haplotype which is commonly found with Europeans that have Celiac Disease. Super B8 contains the DQ2.5 haplotype (DQA1*0501:DQB1*0201). Therefore anyone who has celiac disease and is of NW european ancestry is about 3 to 4 times more likely, simply by linkage to have the IgA-Less phenotype. The nodal peak for DQ2.5 is in the sardinian/basque population while the frequency in the Irish, Welch, ish is high (~20%) which means that close to 1/3rd of the population bears DQ2.5, the IgA less allele is found only in some of these. Similar but lower frequencies are found in the Scandinavian and Goth/N. Slavic derived populations of eastern europe. The other susceptibility DQ type is DQ8, I have not read of an association between IgA-less, yet. The risk for DQ8 mediated disease is nodal in mesoamerican/southamericans, bedohin, northern europeans, eastern asians, scandinavians and iberians. The bottom line is if your ancestry is 'richly' from NW europe Northern or western) and you have CD, there is a pretty good chance you may be IgA-less. The causative association with CD is unclear, it does have an association, however, with misdiagnosis. The IgG from IgA-less CD individuals is fairly affective positive reaction with hum-tTG, and therefore the IgG test of Anti-tTG antibodies is the way to go. The test for alpha-glaidin reaction is not effectively diagnostic. If you are however IgA-less and react with alpha gliadin chances are you have CD than if you are not IgA-less. The two invasive tests are upper small intestine biopsy for mucousal flattening, there are false negatives associated with this test because of patchy villous atrophy. Recent papers suggest that some patients may only have elevated intraepithelial lymphocytes for months to years before clinical recognition is made. A good strategy here is 1. Test IgA If IgA-high a. Sample gliadin antibody b. Sample tTG antibody C. Get High Res DQ typing done. If DQ2.5 of DQ8 and If gliadin Ab high or tTG high then assume CD. Dubious need for further testing if positive. If IgA-less a. DQ type is probably 2.5 b. Sample anti-gliadin IgG c. Sample tTG-IgG If b or c high assume CD. Dubious need for further testing Note the trans type DQA1*0202:DQ1*0202/DQA1*0505:DQA1*0301 can produce the " DQ2.5 " isoform. If DQ type is 2.5, " trans " 2.5, or 8 and the antibody recognition is below clinical limits then: A. Mucousal biopsy. Flattening = Positive B. Intraepitheal lymphocyte quantitation. Elevated = Positive. Avoid gluten challenges. Lifelong risk for certain diseases are elevated as a result of continued gluten consumption. This includes irrevesible autoimmune diseases and lymphoma. A young child will probably 'tolerate' such challenges better than an adult who has years of exposure to gluten, although the reaction can be more severe in children. As for sibling tests. IIRC depending on the population between 1/4 and 1/16 children who have a DQ 2.5 or DQ8 will spontaneously convert to CD+ in their lifetime. Since the child is IgA less you can assume the child probably has DQ2.5. What this means is that the child may convert to CD+ anytime in its life. This is actually a good thing because one knows what symptoms to look for and how to test. Early diagnosis knowing risk is much much better than belated diagnosis because the risk was unknown. In general, most individuals who have a sibling with CD and who later get CD generally contract the illness within 5 years or so when the sibling got the disease. The other risk factors (many and most unknown) for CD appear to affect the age of onset. Diabetes {I) is also a factor amoung siblings, particularly europeans, and it is unclear whether the two diseases are dependent or independent of each other, but if the sibling is a male has type I diabetes and CD there is a much higher risk in the family that a male with Type I diabetes will also have CD, and vice versa, if the male has CD, then also risk for Type I diabetes. The type I/CD linked risk is affected by factors that appear to be nodal in the Channel region of NW europe. This risk is early/very early onset for both diseases. So not only does one know what to look for, but about what time to look for it, and other potential signs of disease. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 24, 2006 Report Share Posted February 24, 2006 Can you post references for these papers? > -----Original Message----- > From: Philip Deitiker > The two invasive tests are upper small intestine biopsy for mucousal > flattening, there are false negatives associated with this test because > of patchy villous atrophy. Recent papers suggest that some patients may > only have elevated intraepithelial lymphocytes for months to years > before clinical recognition is made. --- [This E-mail scanned for viruses by Declude Virus] Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 25, 2006 Report Share Posted February 25, 2006 wow! thanks for the info. i will probably have to read through it several times for it all to make sence to me. one of my girls had a biopsy that was negative for damage----but she had a raised level of intrepithelial lymphocytes in one area. i think that we have been able to catch the disease pretty early in our girls before a lot of damage could take place. my husband and i are both from big families and we have discovered that if you go back in our geneology that we have an ancestral line that is connected. i don't know if it is by blood or by marriage, but i will be interested to look it up some time. as far as we know, no one in either of our families has ever been diagnosed with celiac disease, although there are quite a few autoimmune diseases in our families. i am hoping my son does not have celiac also, but according to your info, it sounds like there is a possibility that he will eventually have it. christine Quote Link to comment Share on other sites More sharing options...
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