Guest guest Posted February 2, 2001 Report Share Posted February 2, 2001 Natural care tips for counseling on fibromyalgia > The Fibrom-L Community Update - http://www.fibrom-l.org > > --------------------------- ListBot Sponsor -------------------------- > Start Your Own FREE Email List at http://www.listbot.com/links/joinlb > ---------------------------------------------------------------------- > > Editors Note: Here is a Pharacist's recommendation to other Pharmacists > for counselling patients with FMS using Vitamins and Suppliments. > > Natural care tips for counseling on fibromyalgia. > Author/s: B. R.ph., D.h.m., D.h.ph., N.m.d. Lavalle > Issue: August 24, 1998 > > Fibromyalgia is a soft tissue, non-articular rheumatic syndrome with > symptoms of chronic aches, pains and stiffness, with trigger points or > specific sites of exaggerated tenderness. With as much as 4 percent of the > population suffering from this disease, modem medical science has yet to > find a cure or even to treat this problem effectively. Fibromyalgia bears > a striking resemblance to chronic fatigue syndrome (CFS) and mainly > affects women aged 25 to 50, with the female-to-male ratio being > approximately 5:1. Fibromyalgia symptoms may be triggered by a number of > factors, including overexertion, stress, lack of exercise, anxiety, > depression, lack of sleep, trauma, extreme temperature and/or humidity > changes and infectious diseases. Fibromyalgia diagnosis is based on > specific site tenderness points, which are assessed by a variety of > techniques. These tender points are located on positions on the body that > have been most frequently reported to cause problems in fibromyalgia > patients. The American College of Rheumatology has developed several > criteria for assessment of fibromyalgia patients: * Diffused > musculoskeletal pain for at least three months. * Stiffness that worsens > in the morning. * Tenderness to palpation of at least 11 of the 18 tender > points. * Sleep disturbances. * Fatigue and/or anxiety. * Depression. * GI > disturbances. * Subjective soft tissue disturbances. * Cardiovascular > complaints (dizziness, palpitations). Possible causes Studies have shown > that victims of fibromyalgia appear to have microcirculatory problems, > along with mitochondrial damage and abnormally low phosphate levels, > suggesting an energy-deficient state of the muscular [tissue.sup.(1)(2)]. > Muscle hypoxia may develop, leading to fatigue and other symptoms, such as > pain. Glucose has the primary function of providing fuel for the body. It > does this in two ways. First, through glycolysis or the breakdown of > glucose into pyruvic acid and at times lactic acid (anaerobically > produced). The second pathway is the conversion of pyruvic acid, in the > presence of oxygen, to carbon dioxide and water. A by-product of this > conversion is the production of ATP in the Krebs cycle. Under various > stresses, the amount of ATP production may not be able to keep up with the > demand, thereby causing fatigue, muscular aches and other problems. > Because the Krebs cycle is relatively slow in production, the glycolytic > pathway is utilized by the body in many situations to produce energy; > however, this leads to a production of dlactic acid, which diffuses and > accumulates into the muscular tissue. Fatigue usually is correlated with > the depletion of glycogen stores and an increase in lactic acid buildup. > These are hallmark traits in individuals suffering from symptoms of > fibromyalgia. Recent evidence suggests that magnesium deficiency may be > crucial in development of symptoms of [fibromyalgia.sup.3]. Magnesium is > necessary in most biochemical processes, including ATP synthesis and > subsequent cellular energy production. Mitochondrial uptake and > accumulation of magnesium are directly related to the uptake of phosphate > required for ADP phosphorylation. Of particular interest is that magnesium > is necessary in aluminum detoxification in the body, and aluminum inhibits > glycolysis and oxidative phosphorylation, resulting in decreased > intramitochondrial ATP production. Additionally, due to its high affinity > for phosphate groups, aluminum blocks the absorption and utilization of > phosphates vital to the synthesis of ATP. Aluminum toxicity is known to > cause metabolic disturbances and has been implicated in Alzheimer's > disease, and detoxification is critical to keep the body and mind healthy. > Researchers have found that in addition to adequate amounts of magnesium > supplemented in the diet, malic acid supplementation may also be > beneficial in improving the symptoms of aluminum toxicity and fibromyalgia > [specifically.sup.(3)(4)]. Also, irritable bowel syndrome, which is a > smooth muscle dysfunction specifically in the gut causing diarrhea, cramps > or dry constipation, has been implicated in fibromyalgia. IBS individuals > report bloating and a feeling of fullness or stretching. Fibromyalgia > patients frequently complain of GI disturbances, commonly caused by IBS. > Proper nutrition and dietary supplementation is imperative in improving > symptoms of IBS and fibromyalgia. Leaky gut syndrome is a condition that > may cause IBS, and also needs to be addressed in the fibromyalgia patient. > This syndrome is the erosion of the microvilli of the mucosal lining, > allowing larger than normal molecules, such as proteins, to enter the > bloodstream, causing fatigue and resulting muscular pain among other > problems. Candida overgrowth is common in leaky gut syndrome, caused by > various factors, including antibiotic use. The use of NSAIDs, aspirin and > other acidic medications may also contribute to leaky gut syndrome. > Correction of these problems is essential in treating the fibromyalgia > patient. Improvement of the underlying metabolic and physiological > imbalances, including leaky gut syndrome, IBS and magnesium deficiency, is > essential. The following protocol may be effective in relieving the > symptoms of fibromyalgia. Do not discontinue any prescribed medications > without consulting a physician. Natural tips for counseling fibromyalgia > patients * A quality multivitamin daily. * Caprylic acid or grapefruit > seed extract (liquid or tablets): Use 1 tablet tid-qid or 5 drops in water > tid-qid. * Acidophilus/bifidus: Adults: one-half teaspoonful qid-bid mixed > in juice or water. * Magnesium malate: 1,200-2,400 mg daily in divided > doses. * Adrenal complex tablet (with B complex): 1 tablet 2-3 times > daily. * Antioxidants (use at least two of the following): * Green tea, > 100-300 mg bid, standardized to 50 percent polyphenols and 40-65 percent > catechin fraction per dose. * Coenzyme Q1O, 20-50 mg daily. * Alpha-lipoic > acid, 10-50 mg daily. * Vitamin E, 4001U daily. * Turmeric, 300 mg > bid-tid, standardized to 90 percent curcuminoids/dose. * Bilberry, 80-240 > mg daily in divided doses, standardized to 25 percent anthocyanidins/dose. > * Stinging nettle leaf (to help eliminate excess uric acid): 250-500 mg > tid-qid; freeze dried leaf preferred. * Homeopathic arthritis/rheumatism > formula: One tablet qid, sublingually. * Peppermint oil (entericcoated > tablets, not mints): 1 tablet qid. Be sure that an appropriate diet of > plenty of fresh fruits and vegetables (organically grown, if possible) and > limited refined foods and sugars is followed. Good sources of dietary > magnesium include: * Soybean products. * Whole wheat flour (not in > hypersensitive individuals). * Buckwheat flour. * Almonds. * Cashews. * > Rice. * Most legumes. Many prescription medications may aggravate the > symptoms of fibromyalgia, and appropriate counseling and alerting the > physician is necessary in patients presenting symptoms of fibromyalgia. > Medications include: * Antibiotics--causes imbalance in normal microflora, > leading to leaky gut syndrome. * NSAIDs/ASA--causes gut erosion and > irritable bowel syndrome. * Anticholinergic agents--dry secretions, > increasing constipation. * Oral contraceptives. * Diuretics. If properly > diagnosed, and with appropriate diet and dietary supplementation, > fibromyalgia can be effectively controlled, allowing millions of suffering > individuals to live pain-free, productive and fulfilling lives. > References: 1. G. Ferracopoili, et al., " Neuroendocrinologic Findings in > Primary Fibromyalgia (Soft Tissue Chronic Pain Syndrome) and in Other > Chronic Rheumatic Conditions, " J Rheumatology 17(1990): 1241-54. 2. A.T. > Masi, et al., " Concepts of Illness m Populations as Applied to > Fibromyalgia Syndrome, " Am J Med 51(1986): 19-25. 3. G. E. Abraham, et > al., " Management of Fibromyalgia: Rationale for the Use of Magnesium and > Malic Acid, " J Nutri Med 3 (1992): 49-50. 4. J. L. Domingo, et al., > " Citric, Malic, and Succinic Acids as Possible Alternatives to > Deferoxamine in Aluminum Toxicity, " Clin Tox 26 (1,2) (1988): 67-79. > > COPYRIGHT 1998 Lebhar-Friedman, Inc. > > COPYRIGHT 2000 Gale Group > ************************************************************ > Chip publishes and maintains The > Fibrom-L Community Website, <http://www.fibrom-l.org> dedicated to the > Fibrom-L Email Discussion. (a privately owned site not affiliated with > MIT) Join our mailing list! > > ************************************************************ > > Health Information Disclaimer > > The Fibrom-L Community provides resources for informational purposes. > Health information should always be carefully reviewed with your health > care provider. The Fibrom-L Community will not be held responsible for > misuse of information or any adverse effects of recommendations stated in > these resources. > > Some resource sites that represent commercial ventures are included > because they are also of informational value. The Fibrom-L Community does > not recommend the use of any particular company or product. > > The views or opinions stated in the resources collected here do not > necessarily reflect those of the Fibrom-L Community, or its owner, Chip > .. 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