Guest guest Posted November 2, 2000 Report Share Posted November 2, 2000 Has anyone ever heard of the use of a medication called methyltrexate in treating MSA or any related symptoms? Suzanne Grimmesey-Kirk, MFT Quality Care Management Voice: 884-1647 FAX: 884-1633 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 2, 2000 Report Share Posted November 2, 2000 I believe my sister took this for r. arthritis. Debbie Debbie White dwhite@... > Re: Medication > > > Has anyone ever heard of the use of a medication called > methyltrexate in treating MSA or any related symptoms? > > > Suzanne Grimmesey-Kirk, MFT > Quality Care Management > Voice: 884-1647 > FAX: 884-1633 > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 2, 2000 Report Share Posted November 2, 2000 Where did you hear of this, Suzanne? And for whom are you inquiring? What are the benefits of the medicine - fill us in! >>> " Suzanne Grimmesey-Kirk " 11/02/00 08:28AM >>> Has anyone ever heard of the use of a medication called methyltrexate in treating MSA or any related symptoms? Suzanne Grimmesey-Kirk, MFT Quality Care Management Voice: 884-1647 FAX: 884-1633 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 2, 2000 Report Share Posted November 2, 2000 Suzanne, I see methotrexate, which is primarity a cancer fighting med, but sometimes used for arthritis or psoriasis. However, it has some severe side effects and they should be fully explaned to you before you go on it. It seems to be a chemo drug. See it here: http://www.intelihealth.com/IH/ihtIH/WSIHW000/19689/20313/223060.html Take care, Bill and Charlotte --------------------------------------------------------------------------- Suzanne Grimmesey-Kirk wrote: > Has anyone ever heard of the use of a medication called methyltrexate in treating MSA or any related symptoms? > > Suzanne Grimmesey-Kirk, MFT > Quality Care Management > Voice: 884-1647 > FAX: 884-1633 > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 2, 2000 Report Share Posted November 2, 2000 I work in the Mental Health Department for my county. I work closely with Doctors (Psychiatrists) and Nurses. When I was recently sharing of my father's diagnosis of MSA with one of my co-workers, they asked if the mentioned medication had been tried. Although the person giving this suggestion knows nothing of MSA, they mentioned that this medication has shown to be helpful in slowing down the progression of other auto immune diseases, some being neurodegenerative. As I haven't heard of this medication before through this list or in my father's care, I just thought I would see if others had heard anything. Suzanne Grimmesey-Kirk, MFT Quality Care Management Voice: 884-1647 FAX: 884-1633 >>> GRIMMESEY-E@... 11/02/00 10:40AM >>> Where did you hear of this, Suzanne? And for whom are you inquiring? What are the benefits of the medicine - fill us in! >>> " Suzanne Grimmesey-Kirk " 11/02/00 08:28AM >>> Has anyone ever heard of the use of a medication called methyltrexate in treating MSA or any related symptoms? Suzanne Grimmesey-Kirk, MFT Quality Care Management Voice: 884-1647 FAX: 884-1633 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 2, 2000 Report Share Posted November 2, 2000 I agree and have read and found the same information. This is the reason why I wondered if others had heard of it being used for the treatment of MSA - as it didn't seem to be a match. I (nor my father who is dx) have been prescribed its use. Thanks for your reply! Suzanne Grimmesey-Kirk, MFT Quality Care Management Voice: 884-1647 FAX: 884-1633 >>> bwerre@... 11/02/00 10:49AM >>> Suzanne, I see methotrexate, which is primarity a cancer fighting med, but sometimes used for arthritis or psoriasis. However, it has some severe side effects and they should be fully explaned to you before you go on it. It seems to be a chemo drug. See it here: http://www.intelihealth.com/IH/ihtIH/WSIHW000/19689/20313/223060.html Take care, Bill and Charlotte --------------------------------------------------------------------------- Suzanne Grimmesey-Kirk wrote: > Has anyone ever heard of the use of a medication called methyltrexate in treating MSA or any related symptoms? > > Suzanne Grimmesey-Kirk, MFT > Quality Care Management > Voice: 884-1647 > FAX: 884-1633 > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 2, 2000 Report Share Posted November 2, 2000 Suzanne, I took methotrexate as one of the three chemotherapy drugs with CMF chemotherapy for breast cancer. I do not know what else it is used for but bet others on this line do. Phoenix Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 2, 2000 Report Share Posted November 2, 2000 That's very interesting, Suzanne! Just wanted to share (might as well share with the group...) that at your Dad's Neurology appointment this a.m., Dr. Rosenfeld said that he sees improvement in Dad's eye tracking! (couldn't really follow the doc's finger last time as he moved it horizontally). Ill tell you, any good news is welcome! To balance out the appointment, however, we were then sent to X-ray, as Dad's hip has been hurting somewhat from a recent fall (not broken or he couldn't walk, but could be bruised.) Things must be o.k. because the doctor hasn't called - and we leave on vacation tonight, so I don't want any bad news!!! Elaine Grimmesey (Suzanne's Mommy) >>> " Suzanne Grimmesey-Kirk " 11/02/00 10:50AM >>> I work in the Mental Health Department for my county. I work closely with Doctors (Psychiatrists) and Nurses. When I was recently sharing of my father's diagnosis of MSA with one of my co-workers, they asked if the mentioned medication had been tried. Although the person giving this suggestion knows nothing of MSA, they mentioned that this medication has shown to be helpful in slowing down the progression of other auto immune diseases, some being neurodegenerative. As I haven't heard of this medication before through this list or in my father's care, I just thought I would see if others had heard anything. Suzanne Grimmesey-Kirk, MFT Quality Care Management Voice: 884-1647 FAX: 884-1633 >>> GRIMMESEY-E@... 11/02/00 10:40AM >>> Where did you hear of this, Suzanne? And for whom are you inquiring? What are the benefits of the medicine - fill us in! >>> " Suzanne Grimmesey-Kirk " 11/02/00 08:28AM >>> Has anyone ever heard of the use of a medication called methyltrexate in treating MSA or any related symptoms? Suzanne Grimmesey-Kirk, MFT Quality Care Management Voice: 884-1647 FAX: 884-1633 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 2, 2000 Report Share Posted November 2, 2000 Suzanne, Could it have been misspelled and should have been " Methotrexate " which is an anti-inflammatory drug? Jim S Re: Medication > Has anyone ever heard of the use of a medication called methyltrexate in treating MSA or any related symptoms? > > > Suzanne Grimmesey-Kirk, MFT > Quality Care Management > Voice: 884-1647 > FAX: 884-1633 > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 9, 2003 Report Share Posted August 9, 2003 Hi Stacie, I was on Imuran for a couple of months, but for me, it sent my liver enzymes up and the MD took me off it. It wasn't until I weaned off over a weeks time, that I realized just how much the inflammation thru out my system had decreased with it. (The rebound wasn't much fun.) I say if you can tolerate it--and honestly, I didn't have much in the way of side-effects, then it could be a very good medication to help with the systemic inflammation. As far as weight gain with it-- I didn't gain weight while I was on it, but I have put on 20 extra pounds from my Effexor XR. I guess it's one of those trade-offs- clinical depression, or obesity. Such a deal. Hope this has helped, Tracie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 9, 2003 Report Share Posted August 9, 2003 Hi Stacie, here is a little what I found on Imuran, I did not see weight gain as one of the side effects... Love to you, GENERIC NAME: azathioprine BRAND NAME: Imuran DRUG CLASS: Azathioprine is classified as an immunosuppressant medication. Azathioprine is used to suppress the immune system in patients who have had kidney transplants. Although its exact mechanism of action in rheumatoid arthritis is not known, its effect in suppressing the immune system appears to decrease the activity of this illness. PRESCRIPTION: yes GENERIC AVAILABLE: yes PREPARATIONS: Tablet: 50mg; It can also be given intravenously. STORAGE: Store at 59 to 77degrees F, in a sealed, light-resistant, container, avoid moisture. PRESCRIBED FOR: Azathioprine is used to inhibit the immune response that causes rejection of kidney transplants. Azathioprine is also used for the treatment of severe, active rheumatoid arthritis. It is considered a "second-line," or "slow- acting" drug and is usually reserved for rheumatoid arthritis patients who do not respond to other first-line or second-line medications. DOSING: Should be taken with food. DRUG INTERACTIONS: Azathioprine can cause an increase in cancer risk when used long-term. This particular risk increases in patients with a prior history of treatment with other powerful immunosuppressants, such as Cytoxan, Leukeran, and Alkeran. It also increases the risk of serious infections. Azathioprine can impair fertility by reducing sperm counts in males. Because azathioprine's toxicity increases when taken with the gout medication allopurinol (Zyloprim), its dose is reduced with simultaneous use. Severely low white blood counts can occur when taken with other drugs that can affect the bone marrow or with ACE-inhibitor class drugs used to treat elevated blood pressure, such as Accupril and Vasotec. The safety and effectiveness for use in children has not been established. PREGNANCY: Azathioprine is transferred to the fetus and is avoided in pregnancy. NURSING MOTHERS: It is also found in breast milk and is not used in nursing mothers. SIDE EFFECTS: The most common serious side effects of azathioprine involve the blood elements and gastrointestinal system. Azathioprine can cause serious lowering of the white blood cell count, resulting in an increased risk of infections. This can reverse when the dose is reduced or temporarily discontinued. Azathioprine can cause nausea, vomiting, and loss of appetite, which can resolve when the dose is reduced or divided through the day. Azathioprine can also cause liver toxicity (in less than 1% of rheumatoid arthritis patients). All patients taking azathioprine require regular blood testing for blood counts and liver function tests for monitoring. Other side effects encountered less frequently include fatigue, hair loss, joint pains, and diarrhea. -- medication Hi everyone:I have a question...is anyone currently taking or has anyone taken Imuran?...if so, can you give me some feedback on how it helped/didnt help you....and the side effects you had with the medication. Also, I am about to start prednisone for the first time next week. My rheum said about 20 mg. is this a definite guarantee for a nice amount of weight gain??...and if you watch what you eat do you still gain, or is the gain mostly b/c of the binge eating?...I am concerned about this b/c I am reading that people put on like 50 pounds with prednisone and I am a small person. HELP!Stacie ~~~~ *** ~~~ *** ~~~ *** ~~~~The Neurosarcoidosis CommunityLive Group Chat:-Mondays & Fridays 10pm EST USAhttp://www.elderwyn.com/neurosarcoidosis/chat.phpMessage Archives and Digest Attachment Pictures:-http://groups.yahoo.com/group/Neurosarcoidosis/messagesMembers Database:-Listings of locations, phone numbers, and instant messengers.http://groups.yahoo.com/group/Neurosarcoidosis/database Bookmarks:-Add a website URL you have found useful.http://groups.yahoo.com/group/Neurosarcoidosis/linksPersonal Complaints or problems:-Please email the moderatorsmailto:Neurosarcoidosis-owner Subscription Details:-1) Individual email - means that every email sent to the list you receive.2) Daily Digest - sends you 25 messages in one single email for you to browse. This is an excellent option if you receive alot of email.3) Web only/No mail - means that you can pop into eGroups at your convenience and receive no email.To modify your subscription settings please visit:- http://groups.yahoo.com/group/Neurosarcoidosis/joinTo subscribe email neurosarcoidosis-subscribe To unsubscribe email neurosarcoidosis-unsubscribe The moderators will not be doing it for you!~~~~ *** ~~~ *** ~~~ *** ~~~~Come stand by my side where I am going,Take my hand if I should stumble and fall,It's the strength and love that you share,That gives me what I need most of all.- Hoyt Axton~~~~ *** ~~~ *** ~~~ *** ~~~~ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 9, 2003 Report Share Posted August 9, 2003 Stacie, I am 5'9" and weighed about 150 when I got married in 1973. My weight crept up over the years to about 200-210, where it stayed for several years. Then I had a sudden onset of fatigue, weight loss (no nausea; just too tired to eat) and other weird symptoms, which I believe was systemic sarc. I had already experienced bilateral hearing loss and a facial palsy the year before, which were attributed to viruses. I lost 35# in about 10 weeks, stayed at that weight for about a year. Then I started Prednisone, first 40mg every other day (by this time I had pulmonary sarc & my lung guy ordered the Pred). I gained a little weight, maybe 10#. About 10 months later, I saw Dr. Stern in Atlanta for the second time & he reviewed my latest brain MRI, wasn't happy with it and said that for NS, I needed 40mg every day, which I started 2/02. I started a slow, steady weight gain over several months, up to about 200 again. I still was easily exhausted, so it was difficult to exercise, plus my legs ache all the time & worse with walking. But, the big jump came after I started Remeron for tremors. It did wonders for the tremors, but I gained about 40# in 2 months. My neuro increased the dosage, because for some strange reason, Remeron is more likely to cause weight gain at lower doses. I have lost 6# in 3 weeks, which is at least a start. Exercise is still very difficult; yesterday I went to the gym; did 10 min. on a stationary bike and 4 laps in the pool. I'm still recovering from that today. If you can exercise even a little, I think it will help with the weight gain. Good luck. Rose in Indiana medication Hi everyone:I have a question...is anyone currently taking or has anyone taken Imuran?...if so, can you give me some feedback on how it helped/didnt help you....and the side effects you had with the medication. Also, I am about to start prednisone for the first time next week. My rheum said about 20 mg. is this a definite guarantee for a nice amount of weight gain??...and if you watch what you eat do you still gain, or is the gain mostly b/c of the binge eating?...I am concerned about this b/c I am reading that people put on like 50 pounds with prednisone and I am a small person. HELP!Stacie ~~~~ *** ~~~ *** ~~~ *** ~~~~The Neurosarcoidosis CommunityLive Group Chat:-Mondays & Fridays 10pm EST USAhttp://www.elderwyn.com/neurosarcoidosis/chat.phpMessage Archives and Digest Attachment Pictures:-http://groups.yahoo.com/group/Neurosarcoidosis/messagesMembers Database:-Listings of locations, phone numbers, and instant messengers.http://groups.yahoo.com/group/Neurosarcoidosis/database Bookmarks:-Add a website URL you have found useful.http://groups.yahoo.com/group/Neurosarcoidosis/linksPersonal Complaints or problems:-Please email the moderatorsmailto:Neurosarcoidosis-owner Subscription Details:-1) Individual email - means that every email sent to the list you receive.2) Daily Digest - sends you 25 messages in one single email for you to browse. This is an excellent option if you receive alot of email.3) Web only/No mail - means that you can pop into eGroups at your convenience and receive no email.To modify your subscription settings please visit:- http://groups.yahoo.com/group/Neurosarcoidosis/joinTo subscribe email neurosarcoidosis-subscribe To unsubscribe email neurosarcoidosis-unsubscribe The moderators will not be doing it for you!~~~~ *** ~~~ *** ~~~ *** ~~~~Come stand by my side where I am going,Take my hand if I should stumble and fall,It's the strength and love that you share,That gives me what I need most of all.- Hoyt Axton~~~~ *** ~~~ *** ~~~ *** ~~~~ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 9, 2003 Report Share Posted August 9, 2003 I am on both Imuran and Prednisone along with Methotrrexate. Imuran is now taking 75mg a day. NO side affects from that one. Prednisone, you can be as careful with your eating as you can, you will still ain weight. You also have to be concerned with Prednisone induced Diabetes. Very hard to escape the Prednisone bloating. Sharon > > From: stasecase@... > Date: Sat Aug 9, 9:10 PM > To: neurosarcoidosis > Subject: medication > > Hi everyone: > > I have a question...is anyone currently taking or has anyone taken > Imuran?...if so, can you give me some feedback on how it helped/didnt help you....and > the side effects you had with the medication. Also, I am about to start > prednisone for the first time next week. My rheum said about 20 mg. is this a > definite guarantee for a nice amount of weight gain??...and if you watch what you > eat do you still gain, or is the gain mostly b/c of the binge eating?...I am > concerned about this b/c I am reading that people put on like 50 pounds with > prednisone and I am a small person. HELP! > > Stacie > > Hi everyone: I have a question...is anyone currently taking or has anyone taken Imuran?...if so, can you give me some feedback on how it helped/didnt help you....and the side effects you had with the medication. Also, I am about to start prednisone for the first time next week. My rheum said about 20 mg. is this a definite guarantee for a nice amount of weight gain??...and if you watch what you eat do you still gain, or is the gain mostly b/c of the binge eating?...I am concerned about this b/c I am reading that people put on like 50 pounds with prednisone and I am a small person. HELP! Stacie ~~~~ *** ~~~ *** ~~~ *** ~~~~ The Neurosarcoidosis Community Live Group Chat:- Mondays & Fridays 10pm EST USA http://www.elderwyn.com/neurosarcoidosis/chat.php Message Archives and Digest Attachment Pictures:- http://groups.yahoo.com/group/Neurosarcoidosis/messages Members Database:- Listings of locations, phone numbers, and instant messengers. http://groups.yahoo.com/group/Neurosarcoidosis/database Bookmarks:- Add a website URL you have found useful. http://groups.yahoo.com/group/Neurosarcoidosis/links Personal Complaints or problems:- Please email the moderators mailto:Neurosarcoidosis-owner Subscription Details:- 1) Individual email - means that every email sent to the list you receive. 2) Daily Digest - sends you 25 messages in one single email for you to browse. This is an excellent option if you receive alot of email. 3) Web only/No mail - means that you can pop into eGroups at your convenience and receive no email. To modify your subscription settings please visit:- http://groups.yahoo.com/group/Neurosarcoidosis/join To subscribe email neurosarcoidosis-subscribe To unsubscribe email neurosarcoidosis-unsubscribe The moderators will not be doing it for you! ~~~~ *** ~~~ *** ~~~ *** ~~~~ Come stand by my side where I am going, Take my hand if I should stumble and fall, It's the strength and love that you share, That gives me what I need most of all. - Hoyt Axton ~~~~ *** ~~~ *** ~~~ *** ~~~~ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 10, 2003 Report Share Posted August 10, 2003 Hi Stacie, First of all, let me say that EVERYONE IS DIFFERENT! But for me, the prednisone caused me to swell and gain 60 lbs in just two months (and like you, I am normally very small or skinny, whatever - I am 5'6 " and always weighed about 120). The Doctors told me to quit eating so much but I did NOT eat hardly at all! The pred made me so nauseated that I could not eat. I have no idea where the weight came from but I still have it and I have been off pred since 2 1/2 years ago....I have tried and tried to lose it but cannot. That is all I can tell you about it.......I know some say that as soon as they quit the pred, the weight goes off, but not for me. Good luck and hang in there......we are here for you. Hugs, Darlene > Hi everyone: > > I have a question...is anyone currently taking or has anyone taken > Imuran?...if so, can you give me some feedback on how it helped/didnt help > you....and > the side effects you had with the medication. Also, I am about to start > prednisone for the first time next week. My rheum said about 20 mg. is > this a > definite guarantee for a nice amount of weight gain??...and if you watch > what you > eat do you still gain, or is the gain mostly b/c of the binge eating?...I > am > concerned about this b/c I am reading that people put on like 50 pounds > with > prednisone and I am a small person. HELP! > > Stacie > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 11, 2003 Report Share Posted August 11, 2003 Tracie, I figured out my problem. I have to time out my pills so they are taken 12 hours apart. I took a dose at 10:00 last night, and when I awoke at 5:00 it was just my usual athritis pain -- I just take 20mg of vioxx and go back to sleep. Then I didn't have to take more methadone until a few minutes ago. The pain doc was adament that I not take the pills until after the pain has started. That's different from most of the pain meds I've taken orally. I am hoping this is a nice Sunday for you. I am insane and am having most of the Kelty clan (parents-in-law, to of my husbands' brothers and one sister and amongst them ten children 8 and under!!!!!) At least Hayden is home == he mowed the lawn earlier and is raking. I just made the worst devilled eggs, but mother was insistant that I use the recipe off the internet. Puke!!!!! Wish me well. The next feat is to sautee a bunch of veggies from our large garden (we already have too many zucchini) and to just plop two large cans of Bush's baked beans into a pan and heat them up (thank God we've come beyond brown sugar and mustard to snap them up. Well, gotta go rest so I can exhaust myself!! tiodaat@... wrote: In a message dated 8/9/03 8:50:38 PM Pacific Daylight Time, rkelty@... writes: I woke up this morning screaming from the pain. ARgggggh. , I thought methadone was supposed to help stop pain? Hon, I am so sorry you're having such a difficult time. NO ONE, should have to wake up screaming from pain. Love to you, Tracie ~~~~ *** ~~~ *** ~~~ *** ~~~~ The Neurosarcoidosis Community Live Group Chat:- Mondays & Fridays 10pm EST USA http://www.elderwyn.com/neurosarcoidosis/chat.php Message Archives and Digest Attachment Pictures:- http://groups.yahoo.com/group/Neurosarcoidosis/messages Members Database:- Listings of locations, phone numbers, and instant messengers. http://groups.yahoo.com/group/Neurosarcoidosis/database Bookmarks:- Add a website URL you have found useful. http://groups.yahoo.com/group/Neurosarcoidosis/links Personal Complaints or problems:- Please email the moderators mailto:Neurosarcoidosis-owner Subscription Details:- 1) Individual email - means that every email sent to the list you receive. 2) Daily Digest - sends you 25 messages in one single email for you to browse. This is an excellent option if you receive alot of email. 3) Web only/No mail - means that you can pop into eGroups at your convenience and receive no email. To modify your subscription settings please visit:- http://groups.yahoo.com/group/Neurosarcoidosis/join To subscribe email neurosarcoidosis-subscribe To unsubscribe email neurosarcoidosis-unsubscribe The moderators will not be doing it for you! ~~~~ *** ~~~ *** ~~~ *** ~~~~ Come stand by my side where I am going, Take my hand if I should stumble and fall, It's the strength and love that you share, That gives me what I need most of all. - Hoyt Axton ~~~~ *** ~~~ *** ~~~ *** ~~~~ Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.