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Zithromax & Klebsiellas

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----Original Message Follows----

From: " Starla " <Starla@...>

" AP List " <rheumaticonelist>

Subject: Re: rheumatic AS/childhood arthritis/infection

Date: Sun, 6 Jun 1999 11:14:53 -0400

From: " Starla " <Starla@...>

Hello Pierre and all,

Pierre, you wrote in part:

> From: Pierre Fontaine <pierre14@...>

> 6- Minocin is effective against most strains of Klebsiellas ....

>

> 8- Strictly speaking, Zithromax is not required. ....

> highly effective against Klebsiellas ....

First let me say I've enjoyed reading your posts very much and appreciate

the thoroughness with which you reply to questions! I do have a question

that I hope you can help me with.

I'm not sure about Minocin, but no where have I read that either doxycycline

or azithromycin are effective against Klebsiella pneumoniae (gram-negative

bacteria). My source re. the Zithro information is:

http://www.pfizer.com/hml/pi%27s/zithromaxmacpi.html

It's 25 pp printed out. I am hoping that my information is simply

inadequate and that you are correct. Another possibility is that I've been

associating the wrong Klebsiella species with AS? Are you aware of any

published source that indicates Zithro is effective against Klebsiella

bacterium? Additionally, I looked up clarithromycin (Biaxin), and it too

did not list K. pneumoniae; however, ciprofloxacin DID.

I truly don't mean to be a fly in the ointment; I'd just like to get things

straight in my own head. Thank you in advance.

Starla (Hazel's daughter)

___________________

Hello Starla,

Hello everyone,

The information on the effectiveness of Minocin against most strains of

Klebsiellas comes from the " Compendium " , the book published every year by

pharmaceutical companies to provide doctors and pharmacists in Canada with a

detailed description of prescription medication in Canada. Also available in

some libraries.

The " Compendium " says that Dalacin, the brand name for oral Clindamycin, has

no effect against Klebsiella pneumoniae.

The " Compendium " , I believe, mentions that Zithromax is effective against

Klebsiella pneumoniae. You should be able to confirm its effectiveness by

downloading the Zithromax info from Mosby's Rx List at:

http://www.rxlist.com

Biaxin is not identified as being effective against Klebsiella pneumoniae.

One last point about the usefulness of Zithromax: Minocin will stop the

replication of bacterias, leaving it to the body's immune system to kill

bacterias. Zithromax is a KILLER of bacterias. Hence, a speedier recovery is

more likely if you combine Minocin and Zithromax.

Dr. Franco prescribes Zithromax, 250 mg, as 2 or 4 capsules per week.

Maximum dosage for long term use of Zithromax is 5 capsules per week.

Pierre

Ankylosing Spondylitis, 18 Years

Antibiotics, 10 Months

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