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Week in Review - Treating Depression

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MEDSCAPE Week in Review - Medscape Today MedPulse®

www.medscape.com/medscapetodayhome

MedPulse is a weekly index of key news and features on Medscape's specialty sites compiled by Medscape's Editors.

Medscape CME: Written and presented by thought leaders in your specialty

Visit the Medscape CME Center: CLICK HERE

FROM THE EDITORReaders often write in to ask why Medscape's Week in Review doesn't include their topic. Our headings actually refer to the specialties we carry on the Medscape site click here

Each site has its own editor and publishes its own content, news, weekly newsletter, and some syndicated content. Some of these articles are highlighted in the very MedPulse that you now reading. If we don't happen to have a site devoted to your specialty, please be patient. We're working on bringing you new pages all the time.

Also this week, check out extensive new offerings on weight management click here And read about new paradigms for depression treatment click here

For technical concerns, contact this address mpmailings@.... Contact the editor at this address weekinrevieweditor@....

Mindy Hung

Editor, Medscape Today

ALSO IN THIS ISSUE:

MEMBER NEWS

USER SUPPORT

NEW FEATURES THIS WEEK

Instant Poll - Reporting Biologic or Chemical Terrorism

In a poll launched on 9/15, 42% said that if you suspected a patient was victim of biologic or chemical terrorism, you would call your hospital's designated terrorism contact. 26% said they would do so when we asked this in 10/01, in the middle of the anthrax attacks. This year, 26% said you would call the local health dept. (35% last year); 22% would the CDC (26% last year); 9% weren't sure what to do (11% last year). 739 readers had responded as of 9/19. Final results available after 9/21.

Medscape, 2002

CARDIOLOGY

Current Approaches and Establishing Future Therapies for the Management of Atrial Fibrillation

New treatments for AF include advances in surgical and catheter-based ablation, biatrial pacing, and alternatives to rhythm control.Medscape Cardiology 6(2) 2002

Who Organized the First Clinical Trial?

J. Willis Hurst, MD, briefly reviews how early British physicians conducted a study for the treatment for scurvy.

CRITICAL CARE

Injurious Ventilation

Although mechanical ventilation is a lifesaving intervention, it may contribute to lung injury and patient morbidity and mortality. Crit Care Med 30(8) 2002

Detection of Acute Illness Clusters, Including Potential Bioterrorism Events

This system complements emergency room- and hospital-based surveillance.

DERMATOLOGY

s- Syndrome, Toxic Epidermal Necrolysis and Hypersensitivity Syndrome

Severe skin adverse drug reactions can result in death. Dermatol Online J 8(1) 2002

DIABETES & ENDOCRINOLOGY

Syndrome and Diabetes

What questions need to be weighed when treating a child with type 1 diabetes and syndrome? F. Cara, MD, shares his thoughts. Medscape Diabetes & Endocrinology 4(2) 2002

Prevalence of Obesity Among Adults with Disabilities

Obesity rates are significantly higher among persons with disabilities, especially among blacks and persons aged 45-64 years.

FAMILY MEDICINE

Newsmaker Interview: New IOM Diet And Exercise Guidelines

The Insitute Of Medicine recommends that 45-65% of calories come from carbohydrates, 20-30% from fat, and 10-35% from protein.Medscape Medical News2002

Restocking the Sample Closet

Can an intervention successfully encourage physicians to alter their prescribing habits?

Secretin Treatment for Autistic Disorder: A Critical Analysis

Assess the effects of secretin on behavior in individuals with autistic disorder.

GASTROENTEROLOGY

Amyloidosis and Occult Gastrointestinal Bleeding

This patient with end-stage renal disease was admitted with abdominal pain, dark stool, and hematocrit drop.Medscape Gastroenterology eJournal 4(5) 2002

Adjuvant Therapy of Colorectal Cancer: The Next Step Forward

Review recent advances in adjuvant treatment for colorectal cancer, the fourth most common cancer occurring worldwide.

HIV/AIDS

Antiretroviral Treatment Interruption and Intermittent Therapy Strategies

E. Gallant, MD, reviews the data and offers clinical recommendations on alternatives to continuous anti-HIV therapy.Medscape HIV/AIDS eJournal 8(5) 2002

Pathogenesis and Epidemiology of Metabolic Abnormalities

It is becoming clear that changes in lipids, glucose metabolism, and body composition are a consequence of the currently available treatments for HIV infection.

Journal Scan

Includes transmission of drug-resistant HIV; effective HAART for advanced disease; amprenavir and lipodystrophy; HIV in prisons; and management of lipoatrophy

HEMATOLOGY-ONCOLOGY

Postoperative Therapy for Malignant Teratoma With High-Grade Sarcomatous and Osteosarcomatous Elements?

An 8-cm pelvic mass was found in a 45-year-old woman who presented with a 2-month history of lower abdominal pain. Medscape Hematology-Oncology 5(2) 2002

Differentiating Acute Promyelocytic Leukemia From Recovering Benign Myeloid Proliferation

Can the morphologic bone marrow aspirates from agranulocytosis patients aid in the diagnosis of promyelocytic leukemia?

INFECTIOUS DISEASES

Vaccine Development for Plague

Although effective antibiotics are available, pneumonic plague is difficult to rapidly diagnose and treat. Two promising subunit vaccines are under development.Medscape Infectious Diseases 4(2) 2002

Beijing/W Strains of Mycobacterium tuberculosis

The ubiquity of these strains and their frequent association with outbreaks and drug resistance underline their import.

MED STUDENTS

Journal Scan

Read about HERS II, breast cancer and breastfeeding, and more.Medscape Med Students 4(2) 2002

MONEY & MEDICINE

Medicaid Drug Cost Controls Create Friction Between States and Pharmaceutical Industry

State initiatives to control Medicaid prescription drug expenditures are faced with legal challenges by the pharmaceutical industry. Drug Benefit Trends 14(8) 2002

Fighting Hand to Hand Over Physician Workforce Policy

The author argues our reliance on free-market principles in determining physician supply is irrational and fuels the conflict over U.S. physician supply and demand.

NEUROLOGY & NEUROSURGERY

Enlarging Brain Lesions in a Patient With AIDS

What's your diagnosis?Medscape Neurology & Neurosurgery 4(2) 2002

Leptomeningeal Dissemination of Pilocytic Astrocytoma Via Hematoma in a Child

A case of recurrent pilocytic astrocytoma with leptomeningeal dissemination (LMD) is described.

NURSING

The Obesity Epidemic

Overweight and obesity are about health, not looks; dietary change and physical activity are prescriptions, not options. Learn how to diagnose and treat metabolic syndrome.

How Should I Assess the Patient With Tinnitus?

Hissing, buzzing, squealing, whining, clicking, or popping noises in the head: Can I assess the patient with tinnitus in the primary care office setting?

Choosing Among the Options for Malpractice Insurance

Which of the 3 options is best for getting malpractice insurance coverage?

OB/GYN AND WOMEN'S HEALTH

Insulin and Oral Antidiabetic Agents for Treatment of Polycystic Ovary Syndrome

A review of the role of insulin in PCOS and the use of insulin-sensitizing agents as therapy. Medscape Women's Health eJournal 7(5) 2002

Elective Cesarean Section: An Acceptable Alternative to Vaginal Delivery?

That women are seeking elective cesarean deliveries may be indicative of failures of modern medicine.

PEDIATRICS

Single-Dose Intravenous Salbutamol Bolus for Managing Children With Acute Severe Asthma

Does a single-dose intravenous salbutamol bolus have the potential to shorten the duration of severe asthma attacks in children in the emergency department?

PCCM 3(2) 2002

PHARMACOTHERAPY

Cost-Effectiveness of Gemifloxacin: Results From the GLOBE Study

This study compares health, economic, and clinical outcomes after randomized treatment with oral gemifloxacin.

Am J Health-Syst Pharm 59(14) 2002

PRIMARY CARE

Treating Depression in the Primary Care Setting

We now know that depression is a chronic and relapsing neurodegenerative disease with a worsening prognosis over time.Copyright © 2002 Medscape

Use of a Calcium Channel Blocker in Depressed Patients

I have found that some patients with depression seem to improve when calcium blockers are discontinued.

PSYCHIATRY

Choosing an Antipsychotic and Why

Knowing how antipsychotic drugs work at specific receptor sites on specific neurons helps the clinician treat each individual patient. Copyright © 2002 Medscape

Clinical Update on the Treatment of Depression

Review strategies that exist to enhance current acute and long-term treatments for depression and modifications to currently available medications.

PULMONARY MEDICINE

Journal Scan

Look at acute interstitial pneumonia, the nicotine lozenge for smoking cessation, and more.Medscape Pulmonary Medicine 6(1) 2002

RADIOLOGY

Krinsky's Case Challenge: Case II

A 37-year-old man plans to donate the right lobe of his liver to his brother who has end-stage viral cirrhosis. Medscape Radiology 3(2) 2002

Quantification of Valvular Aortic Stenosis by Magnetic Resonance Imaging

MRI flow planimetry of the aortic valve orifice may offer a reliable, fast and safe way to noninvasively quantify aortic stenosis.

SURGERY

Laparoscopic Liver Resection for Malignant Liver Tumors

Read about the feasibility, safety, and outcome of laparoscopic liver resection for malignant liver tumors. Ann Surg 236(1) 2002

TRANSPLANTATION

Conference Coverage - European Dialysis and Transplantation Association/European Renal Association

Leading international authorities address frontline research and recent clinical developments in nephrology. Medscape Transplantation 3(2) 2002

Use of Live Kidney Donors With Renal Calculi?

Is the use of live donors with renal calculi for kidney transplantation contraindicated?

Kidney Transplant Recipient With Asymptomatic Candiduria?

Patient is an 80-year-old male renal transplant recipient with a suprapubic catheter and asymptomatic candiduria. How would you treat?

UROLOGY

Benefits of Aspirin and Beta-blockade After MI in Patients With Chronic Kidney Disease

ASA+BB is an underused therapy in acute myocardial infarction patients with underlying kidney disease. Am Heart J 144(2) 2002

LATE-LIFE DEPRESSION: A 6-YEAR PROSPECTIVE STUDY

Examine the correlation between subthreshold depression in the

elderly and clinical outcomes. Review "The Natural History of

Late-Life Depression," featured in an original Medscape Journal Scan. NEW in the Depression Resource Center.

MEMBER NEWS

MULTIPLE SCLEROSIS RESOURCE CENTER FROM MEDSCAPE

Visit the newly enhanced Multiple Sclerosis Resource Center, featuring clinically

focused resources for neurologists and referring physicians. Review latest treatment options and access easy-to-print patient education materials.

USER SUPPORT

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