YEAST? TRY DIFLUCAN 'AND' ANTIHISTAMINE COMBO

[Guest guest]

HI All,

I thought this was interesting seeing how by adding an antihistamine along with an antiyeast medication like oral Diflucan can help with those who have recurring yeast infections.

A smart doctor (I think) will add an antihistamine since far too often it is the inflammation and raw nerves that we are left with and NOT necessarily the yeast. (It may be that overabundance of nerves that don't know when to stop firing)

And it's histamine et al, (cytokine inflammatories) that is part and parcel of that physical process, so by adding an oral anti-histamine (even a topical one like the Benedryl) helps to halt that histamine output and calm those nerves down. Nice to see it in combination from a legitimate source and not me always just talking about it. *grin*.

Dee~

---------------------------------

July 2005, 9:3

Successful Treatment of Refractory Recurrent Vaginal Candidiasis with Cetirizine Plus Fluconazole. Journal of Lower Genital Tract Disease. 9(3):167-170, July 2005.Neves, Nilma A MD; Carvalho, Lucas P MS; Lopes, V MD; Cruz, Alvaro MD, PhD; Carvalho, Edgar M MD, PhD

Abstract: Objective: To determine the prevalence of allergy in patients with recurrent vaginal candidiasis (RVC) and the efficacy of fluconazole (Diflucan) in combination with an antihistamine drug in RVC patients who do not respond to fluconazole alone. Materials and Methods: Participants in the study included 24 women with RVC. All subjects filled out an International Study of Asthma and Allergies in Childhood questionnaire and 23 performed skin prick tests for immediate type 1 hypersensitivity as part of atopy assessment. All subjects were treated with fluconazole 150 mg weekly and were followed every 2 months for 6 months. Those who did not respond to fluconazole alone received cetirizine (Zirtec dt) 10 mg daily in addition to the antifungal medication and were followed up for 6 months. Results: The majority of women had a history of allergy (60%) and 10 of them (43%) had at least 1 positive result of a skin prick test to aeroallergens. Nineteen patients (79%) responded to fluconazole alone. The 5 patients who remained with symptoms had a medical history of allergy and obtained remission when cetirizine was associated with fluconazole. Conclusions: Patients with RVC refractory to standard antifungal therapy and a history of allergy may respond to the combination of antihistamine and antifungal therapy. source: 2005 The American Society for Colposcopy and Cervical Pathology