Guest guest Posted November 8, 2004 Report Share Posted November 8, 2004 In a message dated 11/8/04 7:55:49 AM Eastern Standard Time, skydancer9@... writes: > >Okay, I have a feeling I've asked this before, but how are the newer ones > " better " than the older ones. I thought you or someone said that the older >ones have less reliable " peaks " ...??? >>>>>>>. I'm not sure better is the right term. Different would be more apt. These are the new ones: Lantus is new, within the last few years, and has no peak. It remains steady in the bloodstream for somewhere between 10 and 24+ hours (according to what the rep on the phone told me, though the literature that comes with it says 24). Humalog and Novolog are rapid acting insulins, usually starting to work in 15 minutes, peaking at about 2 hours, and exiting the system in 4 hours (or longer for some people). What makes them new is that Lantus is the first peakless insulin and humalog and novlog are the firt rapid acting insulins. Regular insulin, which is the oldest of all, was all there was for a long time. It starts acting in 30 mins to an hour, peaks at about 3-4 hours, and exits the system in about 8. It saved many lives through the years, but most doctors and patients have moved away from it because of its long time of action - it's still working long after the food is digested and people are prone to lows at 4-5 hours. Some, whos digestion is slow or who have gastropareisis (sp?) which is slow stomach emptyin, have better luck with regular since the rapid insulins would peak too soon. Stacey Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 8, 2004 Report Share Posted November 8, 2004 Vicki wrote: >No, it was NPH, regular and Ultralente which don't require a >prescription. Humalog and NovaLog do. > >The reason the earlier insulins are no prescription is because when >Banting and Best discovered insulin, they made a condition that it >always be available prescription-free. However, the newer insulins got >around this by changing a molecule (or something similar) and thereby >got around it because " technically " it wasn't the same stuff as what >Banting and Best were referring to. Okay, I have a feeling I've asked this before, but how are the newer ones " better " than the older ones. I thought you or someone said that the older ones have less reliable " peaks " ...??? sky Type 2 dx'd 9/04. Low carb diet. Synthroid, Lotril Finds any excuse not to exercise. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 8, 2004 Report Share Posted November 8, 2004 The older insulins such as regular and NPH have irregular peaks that don't necessarily match when you want to eat, so in order to avoid hypos you have to follow a strict meal schedule.. And you have to take the regular insulin way in advance of a meal. And they st ay in your system a long time. OTOH, with the newer " analog " insulins such as Humalog and NovaLog you take it 15 minutes or so before you eat -- whenever that is. If you aren't eating you don't t take it. So it doesn't tie you to an eating schedule. And they're out of your system in hours. The LIlly website has diagrams with action curves on it for all insulins except Lantus, which Aventis makes. I don't know the exact URL but if you do a google with " Lilly insulin " it should get you there. Vicki " old " and " new " insulins > > Vicki wrote: > >>No, it was NPH, regular and Ultralente which don't require a >>prescription. Humalog and NovaLog do. >> >>The reason the earlier insulins are no prescription is because when >>Banting and Best discovered insulin, they made a condition that it >>always be available prescription-free. However, the newer insulins got >>around this by changing a molecule (or something similar) and thereby >>got around it because " technically " it wasn't the same stuff as what >>Banting and Best were referring to. > > Okay, I have a feeling I've asked this before, but how are the newer > ones > " better " than the older ones. I thought you or someone said that the > older > ones have less reliable " peaks " ...??? > > sky > > Type 2 dx'd 9/04. Low carb diet. > Synthroid, Lotril > Finds any excuse not to exercise. > > Quote Link to comment Share on other sites More sharing options...
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