Re: NAC or n-acetylcysteine

[Guest guest]

Hi

I had also read this post about the possibility of NAC not being safe and at the same time, had read a post from the Dental Amalgam list where I belong - I have Chronic Fatigue Syndrome and my mother. Dee, suffers from IPF - ANYWAY...........

Below is a copy of the post from researchers - - I have not informed my mother of this article as NAC seems to be helping her too...!? And so far the studies have only been positive on mice..

, for Dee, IPF 10/06 Mpls. (I do not know who made the initial claim on Breathe-Support)

+++++++++++++++ Mercury Poisoning from Dental Amalgam +++++++++++++++

Researchers at the University of Virginia Health System have discovered troubling side effects of N-acetylcysteine (NAC), a common antioxidant used in nutritional and bodybuilding supplements. NAC can form a red blood cell-derived molecule called nitrosothiol that fools your body into thinking there’s an oxygen shortage, which can lead to pulmonary arterial hypertension (PAH).

PAH is a serious condition, where the arteries in the lungs narrow, increasing the blood pressure in your lungs, causing the right side of your heart to swell.

Lead researcher Dr. Ben Gaston, noted that this is an entirely new understanding of how oxygen is sensed by the body. As it turns out, your body responds to the nitrosothiols, which are created when a decreased amount of oxygen is carried by red blood cells -- not to the amount of oxygen dissolved in the blood.

So far, studies have only been performed on mice. The next step is to determine the threshold at which the antioxidant becomes detrimental to heart and lung function in humans.

Journal of Clinical Investigation September, 2007; 117(9):2592-601 (Free Full Text Report)

Physorg.com September 4, 2007

NAC or n-acetylcysteine

I have been following this forum by way of the daily digest since I was diagnosed with IPF (lung biopsy) this spring. Earlier this month someone on the forum made a comment about NAC not being safe. I believe Bruce, among others, questioned this and were interested in the source of the claim. I have not seen any response posted since. I have been on NAC for over 6 months now and have noticed a significant reduction in my coughing. I have done research before I started taking it as well as over the time since and everything has pointed to NAC being benign. It is important to many of us who use it to know if there is some information that contradicts that. Will the person who made the initial claim please respond so we may know one way or the other?Mike

[Guest guest]

I saw it in the recent issue of Coalition for Pulm. Fib.

NAC or n-acetylcysteine

I have been following this forum by way of the daily digest since I was diagnosed with IPF (lung biopsy) this spring. Earlier this month someone on the forum made a comment about NAC not being safe. I believe Bruce, among others, questioned this and were interested in the source of the claim. I have not seen any response posted since. I have been on NAC for over 6 months now and have noticed a significant reduction in my coughing. I have done research before I started taking it as well as over the time since and everything has pointed to NAC being benign. It is important to many of us who use it to know if there is some information that contradicts that. Will the person who made the initial claim please respond so we may know one way or the other?Mike

[Guest guest]

Mike, I don't know if it will ease your mind or not but my transplant Dr and my pulm. Dr told me to take it. Of course I get the tummy problems so I only take it if I begin coughing. stops it. I react to everything.But NAC is worth it. Love and Prayers, Peggy  ipf 6/04 Florida"Worry looks around, Sorry looks back, Faith looks up." I have been following this forum by way of the daily digest since I was diagnosed with IPF (lung biopsy) this spring. Earlier this month someone on the forum made a comment about NAC not being safe. I believe Bruce, among others, questioned this and were interested in the source of the claim. I have not seen any response posted since. I have been on NAC for over 6 months now and have noticed a significant reduction in my coughing. I have done research before I started taking it as well as over the time since and everything has pointed to NAC being benign. It is important to many of us who use it to know if there is some information that contradicts that. Will the person who made the initial claim please respond so we may know one way or the other?Mike