Guest guest Posted June 4, 2000 Report Share Posted June 4, 2000 Elaine wrote: >I do have that article. Besides nipon, it >was later published in the Journal of >Clinical Endocrinology & Metabolism. Elaine, it would be helpful if you quoted a brief section of the message to which you are replying. I don't remember which article was discussed earlier. >In Japan, allergies, especially allergies to >cedar pollen are considered to be the cause >of Graves' disease. I searched the Medline database (Medline, for those who don't know, is a database that contains a huge number of article summaries from biological and medical journals), and I came up with one paper. The paper was based on a single case study: " Onset of Graves' thyrotoxicosis after an attack of allergic rhinitis " , by Y. Hidaka et al, _Thyroid_ 1996 Aug;6(4):349-51. Here is a link to the Medline record in question: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=8875 759 One paper, one patient. If the Japanese have evidence that cedar pollen causes Graves', they are (more or less) keeping it a secret. >A recent Dutch study published in GUT shows >how certain plant leptins like wheat germ, >soy, and other legumes cause immune changes >via alterations in heat shock proteins in >the stomach. " Lectins " , not " leptins " . (Leptin is a hormone that may play a role in obesity. Lectins are proteins that interact with carbohydrates.) Soy wasn't studied -- kidney beans were. The paper included lectins only from wheat germ and kidney beans, not from any other legumes. Also, the paper (see below for a link) did not deal with " immune changes " at all -- unless you define the immune system loosely to include heat shock proteins. Also, the paper made no mention of Graves' disease or even the thyroid in general. The paper in question is: " Decreased levels of heat shock proteins in gut epithelial cells after exposure to plant lectins " , by JH Ovelgönne et al, _Gut_ 2000;46:680-688 (May). The full text of the article may be found at the following web page: http://gut.bmjjournals.com/cgi/content/full/46/5/680 ly, I think it would be a stretch to claim that this article has any relevance to Graves' disease. Certainly, the authors don't claim any such connection. >The HIAP antibodies Dianne recently mentioned >are the Tulane patented antibodies we tried to >discuss last year on the NGDF board. >They're present in 60% of GD patients Apparently, it's 85%, not 60%. See " The interaction of a type A retroviral particle and class II human leukocyte antigen susceptibility genes in the pathogenesis of Graves' disease " by JB Jaspan et al, _Journal of Clinical Endocrinology & Metabolism_, 1996 Jun;81(6):2271-9. The link to the Medline abstract appears below: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=8964 863 & dopt=Abstract >I still would like to hear Jack Spratt's >take on the pokeweed mitogen. I searched the Internet for a connection between someone named " Jack Spratt " and pokeweed, but couldn't come up with anything. Possibly, this topic was discussed on the mailing list before I joined. Since there doesn't seem to be any way to search the mailing list archives, I'll have to ask Elaine if she would elaborate. >[Pokeweed mitogen is] very much linked to GD >development, but I've found little info. Well, if the link is so strong, then why is there so little information available? >Developed by Royal Lee in 1940, oral >tolerance is now being used by AutoImmune >(through s Hopkins) as autoimmune >therapy. I could not find any connection between Royal Lee (a dentist who died in 1967) and oral tolerance. I did, however, find the following sentence about Royal Lee: " In 1963, Lee was described by a prominent FDA official as 'probably the largest publisher of unreliable and false nutritional information in the world'. " The quote was taken from the following web site: http://www.ncahf.org/Newsletters/Oldletter/Vol17/Nl17-5.htm ====================================== Elaine, Perhaps you think I'm picking on you, and you're probably right. However, I think that you have an obligation to check your facts before you post your messages to hundreds of people. In matters of health, one can never be too careful. While Graves' disease is rarely a matter of life and death, it *is* a matter of, er, " grave " importance, and it certainly affects quality-of-life to a great extent. Your posts are often written with an authoritative air, and you do bring up some interesting points. However, you rarely provide references, and your information is apparently not always accurate. It is conceivable that a list member could read your last post and conclude that he or she should stop eating beans and wheat, and should move to a geographic area that's free from cedar trees. I think that such action would be unjustified, to put it mildly. Elaine, you are, of course, free to do as you please. However, my suggestions to you are the following: 1) Check your data carefully before sending it out. 2) Limit the scope of your messages. Often, your e-mails touch on a great deal of different areas without really examining any one subject in depth. 3) Provide references so the rest of us can see the primary sources 4) Explain, in laymen's terms, what relevance your information has to Graves' disease 5) When you discuss theories that may not be accepted by " The Establishment " , please identify those theories as such. I'm not trying to suppress alternative points of view, but I believe that people have a right to know when some particular outlook is not supported by conventional scientific research. Sincerely, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 4, 2000 Report Share Posted June 4, 2000 > > >I do have that article. Besides nipon, it > >was later published in the Journal of > >Clinical Endocrinology & Metabolism. > > Elaine, it would be helpful if you quoted a brief section of the message to > which you are replying. I don't remember which article was discussed > earlier. Sorry to butt in: Elaine is replying here to an email I sent her privately yesterday, forwarding an article that seemed very interesting to me, and asking for her comments on it. Since this article concludes saying that: " It seems that TH2 cells are stimulated in hyperthyroid Graves' disease to secrete excess IL-13, following stimulation of B cells to secrete TRAb and IgE. IgE elevation as a result of aggravating complex (IL-13-IgE synthesis), thus, may play a role in the participation of thyroid autoimmunity rather than its pathogenesis. " .... and in view of the recent debate, I opted not to have it posted and emailed her. And she must have received it among the many messages from egroup-list. That's why she replied here. Here you have the whole abstract: Nippon Rinsho 1999 Aug;57(8):1904-9 [An elevation of serum immunoglobulin E provides a new aspect of hyperthyroid Graves' disease]. [Article in Japanese] Sato A, Yamada T Department of Medicine, Dokkyo Koshigaya Hospital, Dokkyo University School of Medicine. [Medline record in process] Graves' disease is an autoimmune disorder characterized by circulating TSH receptor antibodies (TRAb), the majority of which lies in the immunoglobulin G (IgG) class. However, there may be a role of other immunoglobulins in the induction and maintenance of hyperthyroid Graves' disease. We focus on the role of IgE on these issues. One third of hyperthyroid Graves' disease shows IgE elevation (greater than 170 U/mL). This prevalence is significantly higher than other thyroid diseases and controls, suggesting IgE elevation appears associated with autoimmune Graves' disease. Half of Graves' patients with IgE elevation have hereditary and/or allergic conditions such as bronchial asthma and pollen allergy. There is a significantly smaller decrease in TRAb in patients with IgE elevation than in those with normal IgE during methimazole treatment. The remission rate is significantly less in patients with IgE elevation than in those with normal IgE. These findings suggest that TRAb synthesis is increased when IgE synthesis is stimulated. There is an elevation of interleukin (IL)-13, but not of IL-4, in two thirds of patients with IgE elevation in the absence of detectable helper T-cell-1 marker, IFN gamma. It seems that TH2 cells are stimulated in hyperthyroid Graves' disease to secrete excess IL-13, following stimulation of B cells to secrete TRAb and IgE. IgE elevation as a result of aggravating complex (IL-13-IgE synthesis), thus, may play a role in the participation of thyroid autoimmunity rather than its pathogenesis. PMID: 10483274, UI: 99412772 Regarding searching the archives, just follow this link: /group/graves_support Here I leave you with Elaine. Regards PS to Elaine: thank you, again, for yr feedback on the article. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 4, 2000 Report Share Posted June 4, 2000 A wrote, in part: >Regarding searching the archives, just follow this link: > > /group/graves_support I didn't realize that the archives include a search function. I stand corrected. -- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 19, 2000 Report Share Posted June 19, 2000 Kari, I use a LOT of fresh garlic in many things and have not had that reaction...I hope it isn't one I aquire either as we all love it in my house. Jody ________________________________________________________________________ Get Your Private, Free E-mail from MSN Hotmail at http://www.hotmail.com Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 19, 2000 Report Share Posted June 19, 2000 Sounds like your fingers were swollen! I hope you are not allergic to either, as they are both so delicious! At 09:46 AM 06/19/2000 -0700, you wrote: >Is anyone here allergic to garlic or rosemary? i made dinner last night, >and used those two things, and *something* made my hands feel like...sort of >like I had no fingerprints. Sort of smooth and tight. It was very weird, >and didn't last more than a couple of hours. Is there a Graves-type >reaction to garlic? I remember we discussed that awhile ago, and many said >to stay away from garlic. I only used a teeny bit last night...have used >*much* more than that. > >Just curious, > >Kari > >------------------------------------------------------------------------ >Life's too short to send boring email. Let SuperSig come to the rescue. >http://click./1/5108/5/_/585824/_/961433221/ >------------------------------------------------------------------------ > >------------------------------------- >The Graves' list is intended for informational purposes only and is not intended to replace expert medical care. >Please consult your doctor before changing or trying new treatments. >---------------------------------------- > > Shen Holy Macro! Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 19, 2000 Report Share Posted June 19, 2000 I know! It wasn't uncomfortable, though. Not like hives. It just felt as if...as if someone was oozing out of my skin. They were very slick. But not painful! Just sort of...itchy, but not really. Doh. Hard to explain. I hope it's not either, because I love both. Funny, it's happened before, too, but I've never been able to pin down the food. I'll have to pay more attention. Kari Re: allergies Sounds like your fingers were swollen! I hope you are not allergic to either, as they are both so delicious! At 09:46 AM 06/19/2000 -0700, you wrote: >Is anyone here allergic to garlic or rosemary? i made dinner last night, >and used those two things, and *something* made my hands feel like...sort of >like I had no fingerprints. Sort of smooth and tight. It was very weird, >and didn't last more than a couple of hours. Is there a Graves-type >reaction to garlic? I remember we discussed that awhile ago, and many said >to stay away from garlic. I only used a teeny bit last night...have used >*much* more than that. > >Just curious, > >Kari > >------------------------------------------------------------------------ >Life's too short to send boring email. Let SuperSig come to the rescue. >http://click./1/5108/5/_/585824/_/961433221/ >------------------------------------------------------------------------ > >------------------------------------- >The Graves' list is intended for informational purposes only and is not intended to replace expert medical care. >Please consult your doctor before changing or trying new treatments. >---------------------------------------- > > Shen Holy Macro! ------------------------------------------------------------------------ Make new friends, find the old at Classmates.com: http://click./1/5530/5/_/585824/_/961443904/ ------------------------------------------------------------------------ ------------------------------------- The Graves' list is intended for informational purposes only and is not intended to replace expert medical care. Please consult your doctor before changing or trying new treatments. ---------------------------------------- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 18, 2001 Report Share Posted March 18, 2001 Kim, If you suspect that you are having allergies though, they have a pretty good series of blood tests called the Meridian panel. It wisks your blood around with all kinds of food. Then it is determined what food your are seriously or mildly allergic to. I had this test done and it was very revealing. My GP said the tests are not 100% reliable but they can be a really good indicator. I have eliminated a lot of foods, and I think that it is really helping the overall functioning of my immune system. I dont't know of any other ways to test for food allergies, although for non food stuff they have the stick your back with a bunch of little allergens method..Which was also beneficial. In any event, with Graves, allergies are never a bad thing to have checked. Val Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 24, 2004 Report Share Posted September 24, 2004 Allergies seem to be categoriezed in several levels. There is an official " allergy test " for milk but that only measures levels of tolerance for certain compounds. In other words, not every compound in each food is measured. And also, the measurements seem to only take into account certain things, mostly having to do with blood. Thyroid function/malfunction is not included in an evaluation that determines effects of foods all the time. but the thyroid can be effected by certain compounds. So that is something the tests won't pick up on. And thryoid affects metabolism and influences moods too. Eg, if you have hypo thryoid, you will have symptoms of depression: such as sleepyness, forgetfullness, tired, photophobia. Please tell me what sorts of symptoms your kiddo had re: milk? -- " Batterton Home Imprv. " wrote: Liz, That's very interesting as TJ was alergic to milk products as a baby. Guess I may have been making it worse in letting him have them even when the usual symptoms of alergy weren't showing. I appriciate your suggestion. He did eat a thing of icecream when we went to visit Sun and then was saying later he didn't feel good. Boy have I been messin up. Will sent him a copy and talk to him Sun about stearing away from milk products. Intersting about the Fish thing as I even thought I could see improvement in his mood the days I took Long SIlvers fish. Guess with the fish being good for barin functions that makes good sense. I as well as everyone would love to find solutions to all this very hard disorder. I had also heard a link between Thyroid and Bi-Polar Disorder. As some put on thyroid meds reduced or eliminated the symptoms. Thanks so much for the info. Prayers to all in this quest for wellness! LouAnn in Nebraska liz wrote: > > There is some study being done on hyper-carbo intake, depression, > bi-polar, mood swings, b-vitamins espec B2 Riboflavin, and Omega fatty > acids. > > My son desplayed significant anxiety while on milk; which notably > diminished off milk. Also he loved fish, especially sushi (an odd > favorite for a 3yo!!!!) and his mood was improved with high fish/sushi > intake. Also high A vitamin and Omega/fatty foods such as: stirring > fish oil into foods, tuna, salmon (fresh deep sea Atlantic--farmed > fish do not have proper contents). > > Good foods were: humus, not-processed soy foods, raw vegies esp > carrots and eggplant(?)[yes!]. Kelp and other seaplants. Red meat. > > anxiety producing foods were: processed carbs such as lots of bread > products, esp white bread, french bread. Chips. Milk and its > derivitives incl whey in baked goods. Eggs. > > Milk, for him, was the real culprit. > > I looked into research that was aimed at nutritional components of > autism, bi-polar, anxiety, thyroid, and hypo/hyper glycemia. there > seems to be an overlap with them all. > > Kiddo was able to be really happy being inside himself when: off milk, > on fish, on high high high levels of exercise (+4 hours per day). > > Liz > > -- " Batterton Home Imprv. " wrote: > > .....seroquel .... He use to snore like a freight train as he'd > gain weight .....a ferocious apetite also. ....When I heard borderline > can also cause you to crave carbs. > > Send questions & concerns to WTOParentsOfBPs-owner . > " Stop Walking on Eggshells, " a primer for non-BPs can be ordered via > 1-888-35-SHELL (). For the table of contents, see > http://www.BPDCentral.com > > Quote Link to comment Share on other sites More sharing options...
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