Guest guest Posted November 21, 2004 Report Share Posted November 21, 2004 At 11:45 PM 11/20/04, Alyne A wrote: >I take Metformin XR 2 times a day. 3 x 500 before bed >and 1 x 500 in the morning. This was on the advice of >my CDE and it works for me. I get a small dawn rise >but not much if I eat withing 30 minutes of becoming >vertical. I took my one 500mg metformin this morning at 2 a.m. I'd had two glasses of red wine the evening before right near bedtime, and also took my 600mg of APA, 100mg of L-Arginine, and 500mg of EPO. This morning my BG was 141, a point higher than yesterday. Thing is, I took it an hour earlier so I've not eaten yet and will take it again in another 10 minutes to see what it is at the same time of day. Of course I also ate more carbs in yesterday's dinner than I normally do, so who knows? Given this: " Following a single oral dose of GLUCOPHAGE XR, C max is achieved with a median value of 7 hours and a range of 4 hours to 8 hours. " I *think* that the peak is at 7 hours. So by taking it at 2 a.m. I may have been doing it too late to affect morning numbers. I'm just not sure. I also am not certain if this is a med that takes awhile to show results or, having a limited time in the system (even the XR) I should know very quickly whether this dose is working or not. I think the last. Whoops, time to test again... nuts, 146. I guess I'd better go eat something. >If I recall correctly, Cappie is not on the >extended release version and when she takes it before >meals, it acts sort of like Prandin or Starlix for >her. I think I'd like that better, though I don't want stomach upset, which is why I asked for the XR type. sky Type 2 dx'd 9/04. Low Carb, Metaformin XR (500mg). Some supplements used are: ALA (1800mg), EPO (1000mg), Biotin (15mg), L-Arginine (500mg), CoQ10 (100mg), Chromium Picolate (500mcg), Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 21, 2004 Report Share Posted November 21, 2004 Sky, remember that meters have a +/- 15 to 20% error allowance, so that one point difference in your BG is meaningless. Even taking two tests in the same drop of blood one right after the other may yield differences as much as 20 points, alas. Meters aren't EXACT. Vicki Re: metformin > > At 11:45 PM 11/20/04, Alyne A wrote: > >>I take Metformin XR 2 times a day. 3 x 500 before bed >>and 1 x 500 in the morning. This was on the advice of >>my CDE and it works for me. I get a small dawn rise >>but not much if I eat withing 30 minutes of becoming >>vertical. > > I took my one 500mg metformin this morning at 2 a.m. I'd had two > glasses of > red wine the evening before right near bedtime, and also took my 600mg > of > APA, 100mg of L-Arginine, and 500mg of EPO. This morning my BG was > 141, a > point higher than yesterday. Thing is, I took it an hour earlier so > I've > not eaten yet and will take it again in another 10 minutes to see what > it > is at the same time of day. Of course I also ate more carbs in > yesterday's > dinner than I normally do, so who knows? > > Given this: " Following a single oral dose of GLUCOPHAGE XR, C max is > achieved with a median value of 7 hours and a range of 4 hours to 8 > hours. " > I *think* that the peak is at 7 hours. So by taking it at 2 a.m. I may > have > been doing it too late to affect morning numbers. I'm just not sure. I > also > am not certain if this is a med that takes awhile to show results or, > having a limited time in the system (even the XR) I should know very > quickly whether this dose is working or not. I think the last. > Whoops, > time to test again... nuts, 146. I guess I'd better go eat something. > >>If I recall correctly, Cappie is not on the >>extended release version and when she takes it before >>meals, it acts sort of like Prandin or Starlix for >>her. > > I think I'd like that better, though I don't want stomach upset, which > is > why I asked for the XR type. > > > sky > > Type 2 dx'd 9/04. Low Carb, Metaformin XR (500mg). > Some supplements used are: ALA (1800mg), EPO (1000mg), > Biotin (15mg), L-Arginine (500mg), CoQ10 (100mg), > Chromium Picolate (500mcg), > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 21, 2004 Report Share Posted November 21, 2004 At 09:18 AM 11/21/04, whimsy2 wrote: >Sky, remember that meters have a +/- 15 to 20% error allowance, so that >one point difference in your BG is meaningless. Yes, I figured it was. Sorry, I should have mentioned that when I posted. Even the 146 later on is meaningless. Regardless, it's in the normal morning range for me lately and seemingly not affected by the metformin I took at 2 a.m.. Does this med have to build up in your system? sky Type 2 dx'd 9/04. Low Carb, Metaformin XR (500mg). Some supplements used are: ALA (1800mg), EPO (1000mg), Biotin (15mg), L-Arginine (500mg), CoQ10 (100mg), Chromium Picolate (500mcg), Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 10, 2004 Report Share Posted December 10, 2004 At 08:40 AM 12/10/04, cappie@... wrote: >Sky: I know what the info lit says but that does not mean it always >works exactly that way on each individual. The regular is not supposed >to work the way it does for me either but it does. yehhh. Ah knows, but a-course just gots ta start somewheres. (Okay, it's been one of those days and I had to be silly or go nuts. This way only my spell-checker goes nuts.) >I realize that the extended release form is very diff from the reg met >but it might be worth a shot. I just wonder if having a lower >around-the-clock background/basal dose of the ext release might not >sometimes work better than a high one-shot deal. One would never know >without trying & loses nothing if it does not make a difference as one >can always go back to the once a day higher dosage. It may. I'd like to get the nurse-practitioner to up the dose to 1800 daily but I think it's too soon for her to consider it. On the other hand, I have some refills (must check to see how many) so maybe I can just take it to 3 500mg pills daily, spread out, and see what happens. Another thing I want to do is to completely stop all of my supplements that are supposed to lower BG's. The ALA, EPO, and L-Arginine (which I spell differently every time), C. Picolate, etc. Biotin, too, perhaps. Need to see if any of the BP or Cholesterol meds are biotin antagonists. >I always felt anything was worth trying if it might possibly help--that >is how I found a way to tame my own dawn effect by trying taking my reg >breakfast med whenever I woke to go to the bathroom instead. When it >helped, no one was more shocked than I but hey, who cares, it worked for >me. I don't need to do that at 4am anymore but I still take it around 6 >or 7am which is at least 2 hrs before breakfast & it holds the bg's in >line till I eat. Oh yeh...I forgot about the getting-up-to-go-to-the-bathroom technique. Hmm. I think that with the extended release, though, that won't do it. I could take the last pill a few hours before the lipitor, maybe. If I had some idea if I could take both lipitor and metformin at the same time, I would. sky Type 2 dx'd 9/04. Low Carb, Metaformin XR (1000mg). Supplements: ALA (1800mg), EPO (1000mg), Biotin (15-20mg), L-Arginine (500mg), CoQ10 (200mg), Chromium Picolate (500mcg), Omega 3 (1000-5000mg) Also: 20mg Lipitor, 100mg Cozaar, 25 mg Hydrochlorothiazide and 175mcg Synthroid. This list is TOO long! Quote Link to comment Share on other sites More sharing options...
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