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Re: Metformin problems

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If you don't have the insert, you can find the info at

www.rxlist.com

Good site to bookmark. You put in the med...it tells you the

contraindications.

Vicki

In a message dated 05/27/2003 7:24:50 PM US Mountain Standard Time,

serene_cat@... writes:

> D.,

>

> I'm not on metformin, but with your prescription you should have gotten

> a sheet explaining the side effects etc....check to see if it matches

> those.

>

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Call your doctor, ! Either way your doctor needs to know what is going on

with you.

Kay

Metformin problems

Hello everyone...

I was diagnosed Type 2 April 24th (a little over a month ago). I was on

500mg Metformin twice a day for about two weeks and my doctor wasn't happy

with the results so she increased the dosage to 1000mg 2x/day instead.

Before she increased the dosage I had problems with diahrrea no matter if I

took it before I ate, after I ate, or whenever, and with the increased

dosage it's just as bad and not letting up. Just how long does it take for

the side effects to subside. It's interferring with my quality of life. I

can't go for a long walk, I can't be far from a restroom anytime during the

day. This is getting old FAST.

Another question... This weekend I suddenly came down with a high fever and

horrible body aches and pains and I suppose it was the flu but I had no

appetite. I took the Metformin on an empty stomach twice yesterday and all

day today I've had horrible abdominal pain and cramping... like spams that

reoccur about every 30 minutes with extreme nausea and sometimes diahrrea,

but not always. I mean this has been since the middle of the night until

now - it's still going on and this evening I decided I better eat because

maybe that would help but so far it's not helping. Now is that the

Metformin or flu symptoms? I don't know what's up or down anymore.

Ack!

Through it all however, my BG's have remained fairly stable.

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> If you don't have the insert, you can find the info at

>

> www.rxlist.com

>

> Good site to bookmark. You put in the med...it tells you the

> contraindications.

> Vicki

Yep... have read and re-read everything there is about that drug and it

doesn't tell you anything more than that the gastrointestinal problems

should go away after you've been using it for a while. Does that mean 3

weeks? 3 months? There is nothing specific mentioned. I'm sure it's

different depending on the person. My next doctor appointment isn't until

July and I'm not going to suffer that long, that's for sure. So I'm going

to simply stop taking it and see how it goes and if my numbers stay okay...

if not... then I'll call her office and see if I need a new script or what

she suggests I do.

D.

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.. wrote: " That was enough for me. I'm sticking to Avandia. I'm on 4

mg BID, and

my A1c's for the last year have been 5.3 to 5.0! "

Thanks ... I am going to have to call my doctor. This is driving me

crazy! This weekend I actually feared something was seriously wrong with

me.

D.

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while metformin is supposed to be good for you it can also be dangerous. for us

old times, you might remember that when originally made available it caused some

major health problems. based on what the doctor has told me, plus what the

hospital requires if i go in for any procedure, i do not take metformin if i am

not feeling well or if i am schedule for a procedure...

Dawson wrote:Hello everyone...

I was diagnosed Type 2 April 24th (a little over a month ago). I was on

500mg Metformin twice a day for about two weeks and my doctor wasn't happy

with the results so she increased the dosage to 1000mg 2x/day instead.

Before she increased the dosage I had problems with diahrrea no matter if I

took it before I ate, after I ate, or whenever, and with the increased

dosage it's just as bad and not letting up. Just how long does it take for

the side effects to subside. It's interferring with my quality of life. I

can't go for a long walk, I can't be far from a restroom anytime during the

day. This is getting old FAST.

Another question... This weekend I suddenly came down with a high fever and

horrible body aches and pains and I suppose it was the flu but I had no

appetite. I took the Metformin on an empty stomach twice yesterday and all

day today I've had horrible abdominal pain and cramping... like spams that

reoccur about every 30 minutes with extreme nausea and sometimes diahrrea,

but not always. I mean this has been since the middle of the night until

now - it's still going on and this evening I decided I better eat because

maybe that would help but so far it's not helping. Now is that the

Metformin or flu symptoms? I don't know what's up or down anymore.

Ack!

Through it all however, my BG's have remained fairly stable.

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While it is true that some people have GI upset from metformin, not all

people do. I had no problem with it at all when I took it. Unfortunately it

didn't

lower my BGs very much, either, but this was because I was later found to be

LADA, not type 2, and needed insulin for good BG control.

The only major health problem I know of that metformin can cause are GI

problems - and those are clearly warned about on the package insert. What

problems

are you referring to when you say metformin can be dangerous? (When you said

" for old times " I assume you meant to type " old timers " )...I do believe there's

a contraindication if you have kidney or liver damage but most pills have

some contraindications so this isn't strange or dangerous, either.

You also said you don't take metformin if you're not feeling well or

scheduled for a procedure. In order to work properly, metformin needs to be

taken

consistently and its effect is cumulative, so stopping it for a day for a

procedure or because you're not feeling well isn't likely to accomplish

anything.

OTOH, if you're having a procedure you should definitely stop your aspirin a

few days ahead of time. (You are taking a daily aspirin, aren't you?)

Vicki

In a message dated 05/30/2003 12:27:58 AM US Mountain Standard Time,

rms60521@... writes:

> while metformin is supposed to be good for you it can also be dangerous.

> for us old times, you might remember that when originally made available it

> caused some major health problems. based on what the doctor has told me, plus

> what the hospital requires if i go in for any procedure, i do not take

> metformin if i am not feeling well or if i am schedule for a procedure...

>

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In a message dated 6/6/03 8:09:39 PM Pacific Daylight Time,

fmmama1993@... writes:

> Subj: Re: Metformin problems

> Date: 6/6/03 8:09:39 PM Pacific Daylight Time

>

> I had never been told this, but just today I heard a patient tell his

> anesthesiologist (I work in the OR) that he had stopped his

> GLucophage and teh anesthesiologist said " good " ...I meant to go back

> and ask why we had to do that, but got busy and did not remember to

> do so...I will ask one of htem if I can remember to...I am facing

> potential surgery in AUgust for my sinuses...I should know before

> that time if it's something I should do.

> Jeannine

Jeanine,

A quick search turned up the following---

Metformin may cause life threatening lactic acidosis in perioperative period

(after) if renal dysfunction develops.

Standard practice---discontinue day before or morning of operation

Restart---after operation when renal function is normal

My quick search didn't turn up anything about anesthesia. Go to Google and

search on Metformin +anesthesia +interaction. There are lots of hits and you

will undoubtedly turn up more.

Sounds like a good enough reason to quit before surgery to me!!!

, T2, dx'ed 4/98, controlling with LC, average bg 100mg/dl, last HbA1c

5.6%

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I had never been told this, but just today I heard a patient tell his

anesthesiologist (I work in the OR) that he had stopped his

GLucophage and teh anesthesiologist said " good " ...I meant to go back

and ask why we had to do that, but got busy and did not remember to

do so...I will ask one of htem if I can remember to...I am facing

potential surgery in AUgust for my sinuses...I should know before

that time if it's something I should do.

Jeannine

> >When I had a little surgery in March, I was warned to stop

Metformin.

> >The doctor said it could interact with the anesthesia. Has anyone

> >else been told this?

> >

> >Denis

> >Actos/Metformin T2 dx 7/19/02

>

>

> Hi Denis,

>

> Although I have not heard of any potential interaction, the concern

where

> Lactic Acidosis is concerned is how the Metformin is " cleared " from

the

> body. There is some competition for " kidney time " between Metformin

and

> radiologic contrast materials. It's like trying to get out of the

stadium

> parking lot after a big game: everybody has to wait their turn. The

delay

> in excreting Metformin raises the risk of inducing Lactic Acidosis.

If a

> drug used to anesthetize a person is " cleared " using the same

routes, then

> a problem could arise. I'm not sure if your doc has this concern in

mind,

> or if he has heard of other more direct drug interactions between

Metformin

> and some anesthetics. You might want to discuss this with him

sometime to

> gain a better understanding of his concerns.

>

> Rick

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