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I went to a dermatologist today. He prescribed Accutane. He said I

had a few cea symptons, but mainly cystic acne. I would like to

know if anyone has done the Accutane treatment and what side effects

occurred. I have been doing some reading on the web and I'm not sure

if I want to try Accutane or not. Any thoughts would be helpful.

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Hi,

Let me begin by saying that isotretinoin (Accutane, Roaccutane) is - in

spite of all the horror stories - not a poison. It is a powerful drug

and it can help. But I believe none is spared from the side effects.

Accutane has been discussed before on our group, some entries can be

found in the highlights, but the text below is borrowed from Gillian

Chinns excellent site: http://www.geocities.com/HotSprings/Spa/2738/

I recommend her site for all considering taking Accutane:

" So what's it really like?

If you've been considering taking roaccutane I guess by now you've

heard or seen lists as long as your arm of possible side effects. I

will say it now - DON'T PANIC!

The more serious side effects are actually very rare. What you will

suffer from is dryness. Your skin, lips, hair and eyes will become dry

as the drug inhibits the grease glands. This is one of the ways in

which accutane helps with your acne, although exactly how it works is

not known.

If you're anything like me, the relief at not having to wash your face

three or four times a day may well outweigh the inconvenience of being

dried up. I would advise you to take preventative measures right from

the start, then the dryness

doesn't become too much of a problem. I was on half my maximum dose,

(that's 25mg) which I think is the normal starting dose, and my grease

glands stopped work completely whilst I was on the treatment.

Petroleum jelly (e.g. vaseline) is good for the lips, but too heavy too

be used on the face. One of my main reservations about accutane was

caused by a number of horror stories I heard about monsterous chapped

lips. I believe this can be prevented by using petroleum jelly right

from the start - I used it several times a day, and missing just one

application could cause me to wake up next morning looking dreadful,

but more jelly soon cleared it up again. I was even able to continue

playing the horn in my church music group!

You'll also want to use a good moisturiser on your face - I think

something straightforward like cream E45 is better than exotic

moisturising creams, but take your doctor's advice on this one.

In the end, the only major disadvantage I experienced was being unable

to wear my contact lenses. This is a normal effect, caused by dryness

of the eyes, and seems a small price to pay.

[...] (Reg. birth defect)

Before you are given your medicine, you are required to sign a form [in

UK that is] stating that you are not pregnant, and will use a reliable

form of contraception during and for one month after treatment.

Even if you're a virgin, you are quite likely to be prescribed the

pill, even if you have no intention of becoming sexually active. I

certainly had no luck pursuading my consultant! In the UK,

contraceptives prescribed by a doctor are free, so at least you don't

have to worry about extra expense!

I think the pill is generally the preferred method, so you may have to

start taking it even if you already use a different method. "

And now a learned description of Accutane from a very informative site:

http://www.rxlist.com/cgi/generic/isotret.htm

" Accutane (isotretinoin), a retinoid which inhibits sebaceous gland

function and keratinization, is available in 10-mg, 20-mg and 40-mg

soft gelatin capsules for oral administration. Each capsule also

contains beeswax, butylated hydroxyanisole, edetate disodium,

hydrogenated soybean oil flakes, hydrogenated vegetable oil and soybean

oil. Gelatin capsules contain glycerin and parabens (methyl and

propyl), with the following dye systems: 10 mg - iron oxide (red) and

titanium dioxide; 20 mg - FD & C Red No. 3, FD & C Blue No. 1 and titanium

dioxide; 40 mg - FD & C Yellow No. 6, D & C Yellow No. IO and titanium

dioxide.

Chemically, isotretinoin is 13-cis-retinoic acid and is related to both

retinoic acid and retinol (vitamin A). It is a yellow-orange to orange

crystalline powder with a molecular weight of 300.44. "

Best wishes,

Thor Jonsson,

who had excellent results

taking maximum dose of Roaccutan

for five months.

original article:/group/rosacea-support/?start=71

85

> I went to a dermatologist today. He prescribed Accutane. He said I

> had a few cea symptons, but mainly cystic acne. I would like to

> know if anyone has done the Accutane treatment and what side effects

> occurred. I have been doing some reading on the web and I'm not sure

> if I want to try Accutane or not. Any thoughts would be helpful.

>

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In a message dated 8/14/99 9:23:17 AM Central Daylight Time,

ragnthor@... writes:

<< Hi,

Let me begin by saying that isotretinoin (Accutane, Roaccutane) is - in

spite of all the horror stories - not a poison. It is a powerful drug

and it can help. But I believe none is spared from the side effects.

Accutane has been discussed before on our group, some entries can be

found in the highlights, but the text below is borrowed from Gillian

Chinns excellent site: http://www.geocities.com/HotSprings/Spa/2738/

>>

Thor - Thanks for the post on Accutane. I am seeing a new derm on Tuesday

and suspect that she will recommend it to me. Will post how it goes. Terry

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In a message dated 8/14/99 7:23:26 AM Pacific Daylight Time

ragnthor@... writes:

>One of my main reservations about accutane was

>caused by a number of horror stories I heard about monsterous chapped

>lips. I believe this can be prevented by using petroleum jelly right

>from the start

I had the monsterous chapped lips. It wasnt fun! It didnt help that I

took Accutane in the winter either. I was on 20mg for 3 weeks, then 30mg for

2 weeks, and 40mg for a little over a week. The only lip balm that helped me

was Emu Oil Lip Balm that I ordered from Maple Spring Farms at

www.maplesprings.com

I stopped the Accutane because I wanted to have Photoderm or laser

done and I didnt really have a severe acne component to this. I also didnt

like the side effects. I feel the drug did help in certain ways. It seemed to

reduce the amount of weird bumps that I would get and it was helping bring

down the inflammation.

Some advice for those wondering whether to try Accutane or look into

Photoderm or laser, do the Photoderm first. The wait after stopping Accutane

to have Photoderm or laser done is usually 6 months to one year. I started

having Photoderm done about 3 months after stopping Accutane and everything

is ok. Im very impatient and wont wait that long!

Bill

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Thor,

How long ago were you taking Accutane? Did it produce long-lasting results

for you, or did you need to return to yet another course of Accutane?

Thanks for your information on it and what you did to treat the resulting

dryness of skin, eyes, etc.

Best regards,

Carol

ragnthor@... wrote:

> Hi,

>

> Let me begin by saying that isotretinoin (Accutane, Roaccutane) is - in

> spite of all the horror stories - not a poison. It is a powerful drug

> and it can help. But I believe none is spared from the side effects.

>

> Accutane has been discussed before on our group, some entries can be

> found in the highlights, but the text below is borrowed from Gillian

> Chinns excellent site: http://www.geocities.com/HotSprings/Spa/2738/

>

> I recommend her site for all considering taking Accutane:

>

> " So what's it really like?

>

> If you've been considering taking roaccutane I guess by now you've

> heard or seen lists as long as your arm of possible side effects. I

> will say it now - DON'T PANIC!

>

> The more serious side effects are actually very rare. What you will

> suffer from is dryness. Your skin, lips, hair and eyes will become dry

> as the drug inhibits the grease glands. This is one of the ways in

> which accutane helps with your acne, although exactly how it works is

> not known.

>

> If you're anything like me, the relief at not having to wash your face

> three or four times a day may well outweigh the inconvenience of being

> dried up. I would advise you to take preventative measures right from

> the start, then the dryness

> doesn't become too much of a problem. I was on half my maximum dose,

> (that's 25mg) which I think is the normal starting dose, and my grease

> glands stopped work completely whilst I was on the treatment.

>

> Petroleum jelly (e.g. vaseline) is good for the lips, but too heavy too

> be used on the face. One of my main reservations about accutane was

> caused by a number of horror stories I heard about monsterous chapped

> lips. I believe this can be prevented by using petroleum jelly right

> from the start - I used it several times a day, and missing just one

> application could cause me to wake up next morning looking dreadful,

> but more jelly soon cleared it up again. I was even able to continue

> playing the horn in my church music group!

>

> You'll also want to use a good moisturiser on your face - I think

> something straightforward like cream E45 is better than exotic

> moisturising creams, but take your doctor's advice on this one.

>

> In the end, the only major disadvantage I experienced was being unable

> to wear my contact lenses. This is a normal effect, caused by dryness

> of the eyes, and seems a small price to pay.

>

> [...] (Reg. birth defect)

>

> Before you are given your medicine, you are required to sign a form [in

> UK that is] stating that you are not pregnant, and will use a reliable

> form of contraception during and for one month after treatment.

>

> Even if you're a virgin, you are quite likely to be prescribed the

> pill, even if you have no intention of becoming sexually active. I

> certainly had no luck pursuading my consultant! In the UK,

> contraceptives prescribed by a doctor are free, so at least you don't

> have to worry about extra expense!

>

> I think the pill is generally the preferred method, so you may have to

> start taking it even if you already use a different method. "

>

> And now a learned description of Accutane from a very informative site:

> http://www.rxlist.com/cgi/generic/isotret.htm

>

> " Accutane (isotretinoin), a retinoid which inhibits sebaceous gland

> function and keratinization, is available in 10-mg, 20-mg and 40-mg

> soft gelatin capsules for oral administration. Each capsule also

> contains beeswax, butylated hydroxyanisole, edetate disodium,

> hydrogenated soybean oil flakes, hydrogenated vegetable oil and soybean

> oil. Gelatin capsules contain glycerin and parabens (methyl and

> propyl), with the following dye systems: 10 mg - iron oxide (red) and

> titanium dioxide; 20 mg - FD & C Red No. 3, FD & C Blue No. 1 and titanium

> dioxide; 40 mg - FD & C Yellow No. 6, D & C Yellow No. IO and titanium

> dioxide.

>

> Chemically, isotretinoin is 13-cis-retinoic acid and is related to both

> retinoic acid and retinol (vitamin A). It is a yellow-orange to orange

> crystalline powder with a molecular weight of 300.44. "

>

> Best wishes,

>

> Thor Jonsson,

> who had excellent results

> taking maximum dose of Roaccutan

> for five months.

>

> original article:/group/rosacea-support/?start=71

> 85

> > I went to a dermatologist today. He prescribed Accutane. He said I

> > had a few cea symptons, but mainly cystic acne. I would like to

> > know if anyone has done the Accutane treatment and what side effects

> > occurred. I have been doing some reading on the web and I'm not sure

> > if I want to try Accutane or not. Any thoughts would be helpful.

> >

>

> ------------------------------------------------------------------------

>

> eGroups.com home: /group/rosacea-support

> - Simplifying group communications

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Carol,

I finished my 5 month long Accutane course nine and a half month ago.

It's very rare to have to repeat such a treatment after you get thirty

years old. The last year has been my first since my early teens without

bumps.

I used moisturizers, sun blocks, vaseline and lip balm, eye drops etc.

to counter the side effects, used it frequently and generally, and was

able to keep them at a minimum, although I believe I got them quite

severely. I even got nose bleeds. But then I knew the drug was having

effect, right! :-)

Such a powerful drug should be your last resort though. I had tried

everything in the book before I took Accutane - and have been off

antibiotics of any sort from the time I took my first Accutane capsule.

(I do now want to try antibiotics again for my ocular rosacea but as

I'm having my face electricuted these days my derm wants me to wait; he

thinks antibiotics make me photosensitive and then he can't treat me

with Photoderm).

Thor.

original article:/group/rosacea-support/?start=71

95

> Thor,

> How long ago were you taking Accutane? Did it produce long-lasting

results

> for you, or did you need to return to yet another course of Accutane?

> Thanks for your information on it and what you did to treat the

resulting

> dryness of skin, eyes, etc.

> Best regards,

> Carol

>

> ragnthor@... wrote:

>

> > Hi,

> >

> > Let me begin by saying that isotretinoin (Accutane, Roaccutane) is

- in

> > spite of all the horror stories - not a poison. It is a powerful

drug

> > and it can help. But I believe none is spared from the side effects.

> >

> > Accutane has been discussed before on our group, some entries can be

> > found in the highlights, but the text below is borrowed from Gillian

> > Chinns excellent site: http://www.geocities.com/HotSprings/Spa/2738/

> >

> > I recommend her site for all considering taking Accutane:

> >

> > " So what's it really like?

> >

> > If you've been considering taking roaccutane I guess by now you've

> > heard or seen lists as long as your arm of possible side effects. I

> > will say it now - DON'T PANIC!

> >

> > The more serious side effects are actually very rare. What you will

> > suffer from is dryness. Your skin, lips, hair and eyes will become

dry

> > as the drug inhibits the grease glands. This is one of the ways in

> > which accutane helps with your acne, although exactly how it works

is

> > not known.

> >

> > If you're anything like me, the relief at not having to wash your

face

> > three or four times a day may well outweigh the inconvenience of

being

> > dried up. I would advise you to take preventative measures right

from

> > the start, then the dryness

> > doesn't become too much of a problem. I was on half my maximum dose,

> > (that's 25mg) which I think is the normal starting dose, and my

grease

> > glands stopped work completely whilst I was on the treatment.

> >

> > Petroleum jelly (e.g. vaseline) is good for the lips, but too heavy

too

> > be used on the face. One of my main reservations about accutane was

> > caused by a number of horror stories I heard about monsterous

chapped

> > lips. I believe this can be prevented by using petroleum jelly right

> > from the start - I used it several times a day, and missing just one

> > application could cause me to wake up next morning looking dreadful,

> > but more jelly soon cleared it up again. I was even able to continue

> > playing the horn in my church music group!

> >

> > You'll also want to use a good moisturiser on your face - I think

> > something straightforward like cream E45 is better than exotic

> > moisturising creams, but take your doctor's advice on this one.

> >

> > In the end, the only major disadvantage I experienced was being

unable

> > to wear my contact lenses. This is a normal effect, caused by

dryness

> > of the eyes, and seems a small price to pay.

> >

> > [...] (Reg. birth defect)

> >

> > Before you are given your medicine, you are required to sign a form

[in

> > UK that is] stating that you are not pregnant, and will use a

reliable

> > form of contraception during and for one month after treatment.

> >

> > Even if you're a virgin, you are quite likely to be prescribed the

> > pill, even if you have no intention of becoming sexually active. I

> > certainly had no luck pursuading my consultant! In the UK,

> > contraceptives prescribed by a doctor are free, so at least you

don't

> > have to worry about extra expense!

> >

> > I think the pill is generally the preferred method, so you may have

to

> > start taking it even if you already use a different method. "

> >

> > And now a learned description of Accutane from a very informative

site:

> > http://www.rxlist.com/cgi/generic/isotret.htm

> >

> > " Accutane (isotretinoin), a retinoid which inhibits sebaceous gland

> > function and keratinization, is available in 10-mg, 20-mg and 40-mg

> > soft gelatin capsules for oral administration. Each capsule also

> > contains beeswax, butylated hydroxyanisole, edetate disodium,

> > hydrogenated soybean oil flakes, hydrogenated vegetable oil and

soybean

> > oil. Gelatin capsules contain glycerin and parabens (methyl and

> > propyl), with the following dye systems: 10 mg - iron oxide (red)

and

> > titanium dioxide; 20 mg - FD & C Red No. 3, FD & C Blue No. 1 and

titanium

> > dioxide; 40 mg - FD & C Yellow No. 6, D & C Yellow No. IO and titanium

> > dioxide.

> >

> > Chemically, isotretinoin is 13-cis-retinoic acid and is related to

both

> > retinoic acid and retinol (vitamin A). It is a yellow-orange to

orange

> > crystalline powder with a molecular weight of 300.44. "

> >

> > Best wishes,

> >

> > Thor Jonsson,

> > who had excellent results

> > taking maximum dose of Roaccutan

> > for five months.

> >

> > original article:/group/rosacea-support/?star

t=71

> > 85

> > > I went to a dermatologist today. He prescribed Accutane. He

said I

> > > had a few cea symptons, but mainly cystic acne. I would like

to

> > > know if anyone has done the Accutane treatment and what side

effects

> > > occurred. I have been doing some reading on the web and I'm not

sure

> > > if I want to try Accutane or not. Any thoughts would be helpful.

> > >

> >

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> Some advice for those wondering whether to try Accutane or

look into

> Photoderm or laser, do the Photoderm first. The wait after stopping

Accutane

> to have Photoderm or laser done is usually 6 months to one year. I

started

> having Photoderm done about 3 months after stopping Accutane and

everything

> is ok. Im very impatient and wont wait that long!

> Bill

Bill,

This is true, not under 6 months they say. But in my case I had to take

the Accutane first to get the situation under control before I had the

Photoderm done. Apart from the rosacea papules and pustules and the

accompanying inflammation (I even bled from the worst areas on both

sides of my nose and on spots on my forehead) my skin was so oily that

I had to wipe my face constantly with paper - and it was always black

with dirt. Sometimes after shaving my face looked like a battle field.

Those days are thankfully gone. I only wished I had known about

Accutane earlier.

Thor.

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>Let me begin by saying that isotretinoin (Accutane, Roaccutane) is - in

>spite of all the horror stories - not a poison. It is a powerful drug

>and it can help. But I believe none is spared from the side effects.

I second that. I was on it for 6 months, and chapped lips was my worst

problem. I'd recommend keeping a supply of chap sticks in strategic

places - I had one in the car, one by the bed, one on my desk at work

and one in my handbag. Also you may want to carry a small tube of

moisturiser cream, in case your face starts to feel tight and dry during

the day.

The only other thing is stay out of the sun, as it makes you very

susceptible to sunburn. My dermatologist waited until autumn to

prescribe it for me, so I wouldn't have to worry too much about staying

out of the sun.

>In the end, the only major disadvantage I experienced was being unable

>to wear my contact lenses. This is a normal effect, caused by dryness

>of the eyes, and seems a small price to pay.

I managed to keep wearing my hard contact lenses right through, partly

because I guess they don't dry out the way soft lenses do, and probably

partly due to my own stubbornness!

I kept taking evening primrose oil and vitamin e supplements the whole

time, so I'm not sure if they helped offset the dryness, but it might be

worth a try.

>who had excellent results

>taking maximum dose of Roaccutan

>for five months.

I found my symptoms returned not long after stopping roaccutane, but

there are a number of other factors which may well have influenced this,

so don't let that put you off.

good luck

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