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Can Prolotherapy Treat

Ankylosing Spondylitis?

Ross Hauser, M.D. <hauser_illinois_prolotherapy.htm>

It is an accepted fact in the medical literature that an individual who

presents with four out of the following five symptoms, without having any

trauma to the lower back, has an 80 percent chance of having the diagnosis

of ankylosing spondylitis:

- onset under age 40

- gradual onset

- duration of low back pain over three months

- morning stiffness and better with exercise

Ankylosing spondylitis involves ankylosing, or hardening, of the ligaments

and tendons where they attach to the bone (enthesis).

Patients who gradually overstretch the ligaments of the low back and the

pelvis as a result of repeated injuries (athletics, work requiring duties

that can cause back injury), can gradually start to experience low back

problems in his early 20s and 30s (onset under age 40). If the overstretched

ligaments are not treated and " tightened " , the symptoms may last for months

and years (gradual onset and duration greater than three months).

Patients with ankylosing spondylitis usually suffer from moderate to severe

stiffness and pain in the low back (morning stiffness), which will improve

during the day with activities (better with exercise). The morning stiffness

being caused by the ligaments loosening during sleep. The patient will feel

better with activity as the day goes on as the ligaments begin to tighten.

The great fact for the person with ankylosing spondylitis is that

Prolotherapy helps this condition. Prolotherapy is very effective in

treating ankylosing spondylitis because it treats the exact structures that

are affected by the disease, the tendons and the ligaments where they attach

to the bone.

Prolotherapy and Pain

From Car Accidents

Lawrence Cohen, M.D. <cohen_connecticut_prolotherapy.htm>

(Excerpts from Dr. Cohen's article, Orthopedic Medicine: a Non-surgical

Approach to Chronic Pain)

I see many patients involved in car accidents with persistent neck pain and

headaches who have undergone expensive and unnecessary MRIs, EMGs, physical

therapy and chiropractic treatment aimed at the cervical spine, when

careful examination might have focused treatment at the real source of their

pain elsewhere.

In some instances the perpetuating problem results when the head is whipped

to the side, the scalene muscles yank on their insertion into the first rib

and pull it up out of alignment. This results in a super sensitive spot

where the first rib attaches to the T1 spine, and muscles around it remain

severely triggered, referring pain up the neck to the head, down the medial

scapula and down the arm. In this case, osteopath mobilization followed by

Prolotherapy to the ligament that joins rib to spine and trigger point

injections of the remaining triggered muscles, will resolve the head, neck

and shoulder girdle complaints.

For others, the problem occurs following an accident in which they bounce

back into the car seat at their mid thoracic spine. This can depress one or

two segments of the thoracic spine, reversing the normal kyphotic curve.

Here, the posture changes to compensate, straightening out the cervical

curve and shortening the paraspinal muscles. Restriction and triggering at

mid-thorax refer pain up to the skull and neck. The pain is felt in the neck

and head-not in the back! When asked to flex their neck, patients typically

cannot reach their chin to their chest. Osteopathic mobilization, often

facilitated by neural therapy block to the paraspinal musculature, will

allow resolution.

In another common accident scenario, the person is jamming on the brake with

the right foot while the left foot is hanging loose and the seat is

tethering the pelvis. This may displace the right cuboid (a small bone in

the foot) or, worse, may cause a torsion that shifts the pelvis out of

alignment with respect to the two iliac bones, or to the sacrum that sits

between. The low back may be painful with either one of these conditions,

yet the foot, where the injury really occurred, rarely is. Either one of

these conditions can alter the patient's posture, gait and stance, resulting

in chronic head or neck pain. Osteopathic mobilization and occasionally

Prolotherapy is necessary to obtain correction and relief.

Finally, there are pain patients where the structural problem is in the

neck. These patients typically are okay as long as they keep seeing the

chiropractor or physical therapist every few days, but they can't resolve

the pain. X-rays may show some arthritis, spondylosis, and degenerative disc

changes, which frequently get the blame for the pain.

Here the structural problem involves the ligament and tendon attachments to

bone. There may be a strain or sprain (micro avulsion or rupture of fibers

as the insert into bone), with local tenderness on palpitation, causing

reactive muscle triggering, which generates much of the pain a patient

feels. In addition, recurring somatic dysfunction in the cervical spine

returns within hours or days after each chiropractic or PT treatment.

The most effective treatment is Prolotherapy, a way of repairing the

ligament and tendon injuries and shutting down the " C " pain fiber irritation

present. In Prolotherapy, a hyperosmotic 12 percent dextrose and lidocaine

solution (which may be combines with a chemical irritant as well) is

injected in small amounts at the attachments of tendon and ligament to bone.

This induces the body's healing inflammatory response to repair strained and

frayed ligament, or merely tighten existing ligaments, made lax by narrowing

of disc or joint spaces through degenerative processes. Through repeated

injections, the treated ligaments can have as much as 140 percent the

strength of controls (in animal studies). Prolotherapy can be used at the

neck, low back, knee, shoulder, or any joint to prevent progression of

arthritis and eliminate pain.

The Science Behind Regrowth

and Repair with Prolotherapy

Marc Darrow, M.D,J.D. <darrow_california_prolotherapy.htm>

We subject our joints to wear and tear whether through repetitive movement,

injury, accident or any other number of reasons. Because the connective

tissue around our joints has such poor blood circulation, conventional

treatment maintained that any injury to connective tissue was often

irreparable. This was prior to a study conducted by Y. King Liu.

In a 1983 study of Prolotherapy's effectiveness, Y. King Liu injected five

percent sodium morrhuate solution into the medial collateral ligaments of

rabbits. He found that after five injections, the ligament mass increased by

44 percent, the thickness by 27 percent, and the strength of the ligament

bone junction increased by 28 percent. (Liu Y, Tipton C, Matthes R, Bedford

T, Maynard J, Walmer H. An In Situ Study of the Influence of a Sclerosing

Solution in Rabbit Medial Collateral Ligaments and Its Junction Strength.

Connect Tissue Res 1983;11:95-102.)

Liu's study confirmed the results of an earlier study done by

Hackett, M.D. In 1955 Dr. Hackett and his colleague Dr. D.G.

reported two years experimentation on the effects of the proliferant

Sylnasol when injected into rabbit tendons. (Hackett GS, DG. Joint

Stabilization: An Experimental, Histologic Study with Comments on the

Clinical Application in Ligament Proliferation. Amer J Surg

1955;89:968-973.)

In 48 hours, histological tissue examinations revealed an early inflammatory

reaction surrounding the nerves and blood vessels with lymphocytic (immune

system cells that remove damaged tissue) infiltration throughout the area

between the two tendons and between the tendons and its sheath.

Two weeks after the injection, fibrous tissue was present; lymphocytic

infiltration had diminished, although some was still present, which

indicated that the proliferation of new white fibrous tissue was still being

stimulated.

Lectures, Announcements and Listings

You can now hear Lawrence Cohen, M.D., Marc Darrow, M.D.,J.D. and Ross

Hauser, M.D., anytime you like discussing Prolotherapy on various radio

shows, simply go to http://getprolo.com/prolotherapy_radio_shows.htm

You can also view a 12 minute video from Greenberg, M.D. at

www.prolotherapy-md.com.

Listen to Dr. Marc Darrow every Saturday morning on KRLA-AM Radio in the Los

Angeles Area. Not in the listening area? Listen on-line at

http://www.krla870.com --- Saturday mornings 7:30 AM PACIFIC TIME, 8:30 AM

MOUNTAIN, 9:30 AM CENTRAL, 10:30 AM EASTERN. IN THE LOS ANGELES AREA - TUNE

TO KRLA 870AM

Getprolo.com Physicians

Updated Physician List:

Below is a complete listings of physicians listed on the www.getprolo.com

site through February 12, 2003

ARIZONA

Phoenix Area - Kent L. Pomeroy, M.D.

Phoenix Area/sdale - A. Wasserman, M.D.

Yuma Area - Ellis V. Browning, M.D.

CALIFORNIA <http://getprolo.com/california_prolotherapy.htm>

Anaheim Area - Hanson Wong, M.D.

Los Angeles Area - Donna Alderman, D.O.

Los Angeles Area - Marc Darrow, M.D.

Los Angeles Area - G. Shields, M.D.

Los Angeles Area - Hanson Wong, M.D.

San Diego Area - Kulik, M.D.

San Diego Area - Matson, D.O.

San Diego Area - A. Venn-, M.D.

San Francisco Area - Donna Alderman, D.O.

San Francisco Area - Gene Pudberry, D.O.

Santa Barbara Area - hefsky, M.D.

Santa Area - Terri Su, M.D.

Santa Area - J. Rowan, M.D.

CONNECTICUT <http://getprolo.com/cohen_connecticut_prolotherapy.htm>

Lawrence D. Cohen, M.D.

FLORIDA <http://getprolo.com/florida_prolotherapy.htm>

Ft. Lauderdale - Bach McComb, D.O.

Orlando Area - Kraucak, M.D.

Miami Area - Bernard Miot, M.D.

Miami Area - Alvin Stein, M.D.

Tampa Bay Area - H.G. , M.D.

Tampa Bay Area - S. Todd , M.D.

GEORGIA <http://getprolo.com/georgia_prolotherapy.htm>

Atlanta Area - M. Truett Bridges, Jr., M.D.

Atlanta Area - Mark C. Merlin, D.O

ILLINOIS <http://getprolo.com/illinois.htm>

Chicago Area - Ross Hauser, M.D.

KANSAS <http://getprolo.com/reeves_prolotherapy_kansas.htm>

Kansas City Area - K. Dean Reeves, M.D.

LOUISIANA <http://getprolo.com/fortier-bensen_louisiana.htm>

New Orleans Area - Fortier-Bensen, M.D.

MARYLAND <http://getprolo.com/prolotherapy_maryland_gheen.htm>

Ingrid Gheen, M.D.

MASSACHUSETTS <http://getprolo.com/trister_massachusetts_prolotherapy.htm>

Worcester Area - Jon Trister, M.D.

MINNESOTA <http://getprolo.com/wheaton_prolotherapy_minnesota.htm>

Excelsior Area - Mark T. Wheaton, M.D.

MISSISSIPPI <http://getprolo.com/fortier-bensen_mississippi.htm>

Fortier-Bensen, M.D.

NORTH CAROLINA <http://getprolo.com/north_carolina_prolotherapy.htm>

Blievernicht, M.D.

NEW JERSEY <http://getprolo.com/new_jersey_prolotherapy.htm>

Northern New Jersey - Anwer Rasheed, M.D.

Central New Jersey - Ed Magaziner, M.D.

Southern New Jersey - Greenberg, M.D.

NEW YORK <http://getprolo.com/new_york_prolotherapy.htm>

Buffalo Area - L. Speciale, D.O.

New York City Metro - Lawrence D. Cohen, M.D.

OHIO <http://getprolo.com/nielsen_ohio_prolotherapy.htm>

Toledo Area - Jay W. Nielsen, M.D.

OREGON <http://getprolo.com/oregon_prolotherapy.htm>

Ashland Area - Carl Osborn, D.O.

Ashland Area - hefsky, M.D.

PENNSYLVANIA <http://getprolo.com/pennsylvania_prolotherapy.htm>

Philadelphia Metro - Greenberg, M.D.

Philadelphia Metro - Kab S. Hong, M.D.

RHODE ISLAND <http://getprolo.com/cohen_connecticut_prolotherapy.htm>

Lawrence Cohen, M.D.

SOUTH CAROLINA

<http://getprolo.com/south_carolina_prolotherapy_schwartz.htm>

Greenville Area - Schwartz, M.D.

TEXAS <http://getprolo.com/texas_prolotherapy.htm>

Austin Area - K. , M.D.

Dallas Area - Jim Holleman, D.O.

Houston Area - ph G. Valdez, M.D.

Ft. Worth Area - Teitelbaum, DO

UTAH <http://getprolo.com/prolotherapy_roberts_utah_payson.htm>

Payson - , M.D.

VIRGINIA <http://getprolo.com/virginia_prolotherapy.htm>

Fairfax Area - Mayo Friedlis, M.D.

andria Area - H. Wagner, M.D.

WASHINGTON STATE <http://getprolo.com/washington_prolotherapy.htm>

Olympia - S. Koch, D.O.

Seattle Area - A. Sandler, M.D.

WISCONSIN <http://getprolo.com/wisconsin_faber_prolotherapy.htm>

Milwaukee Area - J. Faber, D.O.

c 2003 Getprolo.com All Rights Reserved

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