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Spencer got a new RX today. I hope it helps with his moods. THERAPEUTIC

CATEGORY

Antidepressant, Tricyclic (Tertiary Amine)

USE

Treatment of various forms of depression, often in conjunction with

psychotherapy; enuresis in children; analgesic for certain chronic and

neuropathic pain

USUAL DOSAGE

Children: Oral (safety and efficacy of imipramine therapy for treatment of

depression in children <12 years have not been established):

Enuresis: ³6 years: Initial: 10-25 mg at bedtime, if inadequate response

still seen after 1 week of therapy, increase by 25 mg/day; dose should not

exceed 2.5 mg/kg/day or 50 mg at bedtime if 6-12 years of age or 75 mg at

bedtime if ³12 years of age

Adjunct in the treatment of cancer pain: Initial: 0.2-0.4 mg/kg at

bedtime; dose may be increased by 50% every 2-3 days up to 1-3 mg/kg/dose at

bedtime

Adolescents: Oral: Initial: 25-50 mg/day; increase gradually; maximum: 100

mg/day in single or divided doses

Adults:

Oral: Initial: 25 mg 3-4 times/day, increase dose gradually, total dose may

be administered at bedtime; maximum: 300 mg/day

I.M.: Initial: Up to 100 mg/day in divided doses; change to oral as soon as

possible

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