Guest guest Posted July 10, 2006 Report Share Posted July 10, 2006 I've forgotten occasionally and have taken it after 2 am, I wonder if it does any good at all. Re: [low dose naltrexone] LDN - take with food? at the conference dr gluck was adamant about that you take it during the specified hours. apparently the body doesn't know if your not sleeping. cyndi On Jul 9, 2006, at 6:24 PM, Peg Janssen wrote: I know it says to take your dose between 9PM and 2 AM, but why? It must be that you should be in "shut-down mode" and ready for sleep. If you are supposed to take it at that time and you work the night shift then your circadian rhythm is different and I would think it would not work the same. It must have something to do with a person sleeping so it can work during that time. Peg -. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 10, 2006 Report Share Posted July 10, 2006 I have on occasion missed mine by 1, and have gone ahead and taken it anyway, sometimes more around 2 or 2:30 am. I wonder if it does anything at all, or if it could have a more negative effect. > > > >> > >> I know it says to take your dose between 9PM and 2 AM, but why? > >> It must be that you should be in " shut-down mode " and ready for > >> sleep. If you are supposed to take it at that time and you work > >> the night shift then your circadian rhythm is different and I > >> would think it would not work the same. It must have something to > >> do with a person sleeping so it can work during that time. > >> > >> Peg > >> > >> -. > >> > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 10, 2006 Report Share Posted July 10, 2006 > > If you are on nights and sleep days wouldn't you work it in the reverse? Take a couple of hours before you go to sleep???????? =========== No, LDN must be in your system during the hours of 2am-4am when endorphins produce the most. Sleep has nothing to do with the way LDN works. If LDN is taken before 9pm then it's already out of your system before 2am and if taken later than 3am it may not work at full capacity during the 2am-4am mark. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 11, 2006 Report Share Posted July 11, 2006 How the heck do you do colors and stuff? > > The following info is from the > www.low dose naltrexone.org website. Just for clarification. > > regards, Arlene > > What dosage and frequency should my physician prescribe? The > usual adult dosage is 4.5mg taken once daily at night. Because of > the rhythms of the body's production of master hormones, LDN is best > taken between 9pm and 3am. Most patients take it at bedtime. > > The brief blockade of opioid receptors between 2 a.m. and 4 a.m. > that is caused by taking LDN at bedtime each night is believed to > produce a prolonged up-regulation of vital elements of the immune > system by causing an increase in endorphin and enkephalin > production. Normal volunteers who have taken LDN in this fashion > have been found to have much higher levels of beta-endorphins > circulating in their blood in the following days. > > > > > > -------------- Original message -------------- > > From: " nstubbs1@ " <nstubbs1@> > > > > > It is supposed to be taken between 9 pm > > > and 12. It initiates a blockade of the > > > opiate receptors in the immune system > > > between 2 a.m. and 4 a.m. The blockade > > > of the receptors between 2 to 4 a.m. is > > > supposed to stimulate the body's own > > > production of endorphins, bring them > > > to a higher, more normal level over > > > time so they will up-regulate the > > > immune system. > > > N- > > > > > > > > > > > > > > > BR>> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 11, 2006 Report Share Posted July 11, 2006 If its taken at 3, then wouldnt it have already missed half of the 2- 4 mark, IE 2-3, are you saying that anytime before 3 has a chance of hitting the latter half of the 2-4 mark, IE 3-4, or more accurately, say, 3:20, or possibly 3:30 to 4 mark. Just how close are we talking about? > > > > If you are on nights and sleep days wouldn't you work it in the > reverse? Take a couple of hours before you go to sleep???????? > =========== > > No, LDN must be in your system during the hours of 2am-4am when > endorphins produce the most. Sleep has nothing to do with the way LDN > works. If LDN is taken before 9pm then it's already out of your > system before 2am and if taken later than 3am it may not work at full > capacity during the 2am-4am mark. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 11, 2006 Report Share Posted July 11, 2006 Well, originally this thread dealt with taking LDN with food, but it grew into what times to take LDN. Sometimes I forget to take my LDN, I'm wondering if I should not even bother to take it at all past a certain time , or should I just take it anyway. Some meds say to resume as normal the next dosing period, some say to take the dose when you remember, and continue as normal the next time. If it's definitively pointless to take it past a certain time, I wouldnt waste it. > > What was this answer pertaining to, what was the question? that gave this > answer. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 11, 2006 Report Share Posted July 11, 2006 lol, ok thx. (But what happens after 3?, sorry, dont hit me):0))))) > > > > > > If you are on nights and sleep days wouldn't you work it in the > > reverse? Take a couple of hours before you go to sleep??????? ? > > =========== > > > > No, LDN must be in your system during the hours of 2am-4am when > > endorphins produce the most. Sleep has nothing to do with the way > LDN > > works. If LDN is taken before 9pm then it's already out of your > > system before 2am and if taken later than 3am it may not work at > full > > capacity during the 2am-4am mark. > > > > > > > > > > > __________________________________________________ > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 11, 2006 Report Share Posted July 11, 2006 lol, no I'm not a skitzo, but I've been accused of worse! I noticed the two names too, it depends on if I answer a post through my email, or if I answer it through the forum. Pennsylvania huh, cant recall any faily living there, I'm originally from Ohio, been in Arizona for quite a while now. > > > > > > If you are on nights and sleep days wouldn't you work it in the > > reverse? Take a couple of hours before you go to sleep???????? > > =========== > > > > No, LDN must be in your system during the hours of 2am-4am when > > endorphins produce the most. Sleep has nothing to do with the way > LDN > > works. If LDN is taken before 9pm then it's already out of your > > system before 2am and if taken later than 3am it may not work at > full > > capacity during the 2am-4am mark. > > > > > > > > > > > __________________________________________________ > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 11, 2006 Report Share Posted July 11, 2006 Dr. McCandless says to take it between 9pm and 11 pm. Don't forget that it takes time for the drug taken orally to get into your system and start to work. And, daylight savings time is an artifact that the circadian rhythm does not recognize. mjh"The Basil Book"http://foxhillfarm.us/FireBasil/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 11, 2006 Report Share Posted July 11, 2006 --- In low dose naltrexone , " Dave Carlin " <davizona@...> wrote: > > But Wesley, you're still ignoring the REAL question, ------------ Dave, take a chill pill! (With or without food, you choose) Phil Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 11, 2006 Report Share Posted July 11, 2006 I don't know of ANY cylces in our bodies that turn on and off like a light switch. Our cycles gradually rise to a peak, then gradually subside. How long the rise takes, how long the peaks last, and how long the decline takes has 'normals'. However, these cycles could fluctuate slightly with individuals (just like our preferred dosages). Surely, the production of endorphins is no different. If I forgot to take my LDN during the specified time, whether or not I would take later would depend 'on how much' later. 2:00 or 2:30, I definitely would still take mine. As far as a negative effect, nothing that I have ever heard would suggest that. After all, the original drug blocked all day and night and still there were no bad effects reported. Taking LDN 'late' probably would keep us from getting as much of a benefit or none at all. > > > > > >> > > >> I know it says to take your dose between 9PM and 2 AM, but > why? > > >> It must be that you should be in " shut-down mode " and ready > for > > >> sleep. If you are supposed to take it at that time and you > work > > >> the night shift then your circadian rhythm is different and I > > >> would think it would not work the same. It must have something > to > > >> do with a person sleeping so it can work during that time. > > > >> > > > >> Peg > > >> > > >> -. > > >> > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 14, 2006 Report Share Posted July 14, 2006 Hello from the road. I haven't been home since 6/30, been camping, thanks to LDN. Am at the Grey Fox Bluegrass Festival.. took a trip to the Library on the way to get some ice for our group, and the Library has good A/C so here I am LOL LDN is supposed to be taken between 9pm and 3am... I say 10pm-3am during daylight savings, but that's JMHO. Others say before 2am... whatever works so you get it in there. I almost always take it after midnight and usually before 2am. Whether I'm working the night shift (12-8a) or am on vacation, as now. I see the subject is about food though.. haven't been getting the emails and not sure the question but I've taken it empty stomach, after eating, etc.. never noticed any difference(s) to speak of.. as long as it's consistently between 9p and 3a. I'll be back next week but not sure if anyone will still be here? wow... " why can't we all just get along? " > > > > I know it says to take your dose between 9PM and 2 AM, but why? It > must be > > that you should be in " shut-down mode " and ready for sleep. If you > are > > supposed to take it at that time and you work the night shift then > your > > circadian rhythm is different and I would think it would not work > the same. > > It must have something to do with a person sleeping so it can work > during > > that time. > > > > > Peg > > > > -- > > I believe it is Larry who works the night shift and takes LDN. Maybe > he'll chime in with his experience. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 14, 2006 Report Share Posted July 14, 2006 Hello from the road. I haven't been home since 6/30, been camping, thanks to LDN. Am at the Grey Fox Bluegrass Festival.. took a trip to the Library on the way to get some ice for our group, and the Library has good A/C so here I am LOL LDN is supposed to be taken between 9pm and 3am... I say 10pm-3am during daylight savings, but that's JMHO. Others say before 2am... whatever works so you get it in there. I almost always take it after midnight and usually before 2am. Whether I'm working the night shift (12-8a) or am on vacation, as now. I see the subject is about food though.. haven't been getting the emails and not sure the question but I've taken it empty stomach, after eating, etc.. never noticed any difference(s) to speak of.. as long as it's consistently between 9p and 3a. I'll be back next week but not sure if anyone will still be here? wow... " why can't we all just get along? " > > > > I know it says to take your dose between 9PM and 2 AM, but why? It > must be > > that you should be in " shut-down mode " and ready for sleep. If you > are > > supposed to take it at that time and you work the night shift then > your > > circadian rhythm is different and I would think it would not work > the same. > > It must have something to do with a person sleeping so it can work > during > > that time. > > > > > Peg > > > > -- > > I believe it is Larry who works the night shift and takes LDN. Maybe > he'll chime in with his experience. > Quote Link to comment Share on other sites More sharing options...
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