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Re: Anyone Know About Titer Levels?

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my son's was similar, so our doctor put him on valtrex..his focus increased

by leaps and bounds!!!

ctlamont wrote:

> They just tested my daughter. Apparently the measles and mumps were

> around 2.2 and 2.4 - but her Rubella came back 152. Any thoughts?

> Thanks

> (mom to Kait asd & nt 28 months)

> psychmjr@...

>

> =======================================================

>

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How old are your kids? Did you just ask your pediatrician to check the titers?

Re: [ ] Anyone Know About Titer Levels?

my son's was similar, so our doctor put him on valtrex..his focus increased

by leaps and bounds!!!

ctlamont wrote:

> They just tested my daughter. Apparently the measles and mumps were

> around 2.2 and 2.4 - but her Rubella came back 152. Any thoughts?

> Thanks

> (mom to Kait asd & nt 28 months)

> psychmjr@...

>

> =======================================================

>

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> How old are your kids? Did you just ask your pediatrician to

check the titers?

My daughter is 28 months old and has ASD. Her DAN! Dr. (Not her

ped.)did a battery of tests on her and this is one of a bunch that

came back red flagged.

(mom to kait & brian 28 months)

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My son is 8, we checked titers 2 years ago because the school nurse was an idiot

and said she would send my son home every time an illness was going around

because

he didn't get his boosters. We checked his titers so she woud know what he did

have

immunity to. Our new doctor is the one that put him on Valtrex, he's been using

it

with other kids in his office that have Autism, with good results.

& Larson wrote:

> How old are your kids? Did you just ask your pediatrician to check the

titers?

> Re: [ ] Anyone Know About Titer Levels?

>

> my son's was similar, so our doctor put him on valtrex..his focus increased

> by leaps and bounds!!!

>

> ctlamont wrote:

>

> > They just tested my daughter. Apparently the measles and mumps were

> > around 2.2 and 2.4 - but her Rubella came back 152. Any thoughts?

> > Thanks

> > (mom to Kait asd & nt 28 months)

> > psychmjr@...

> >

> > =======================================================

> >

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Hey, I'm in the same boat here. We just got our results on titers

back too. My son was 3.33 on measles and 1.53 on mumps, but 121 on

rubella! I called the dr's office and they said this is a common

pattern. Some show NO titers, but those that show it have elevated

titers.

Lynn

Austin 37 months blind and ASD

--- In , " ctlamont " <psychmjr@m...>

wrote:

> They just tested my daughter. Apparently the measles and mumps

were

> around 2.2 and 2.4 - but her Rubella came back 152. Any

thoughts?

> Thanks

> (mom to Kait asd & nt 28 months)

> psychmjr@m...

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Hi, titers are typically used to define the amount of antibodies

present in serum of people who have been exposed to an infection or

immunized against something. Initially titer were expressed as a

serum dilution, e.g. 1:20, 1:40, 1:80, which meant that if you took

the serum from an individual and put the serum on an antigen (the

thing the antibody binds to)the serum and antigen who demonstrate a

reaction (the binding). So if the serum was diluted 80 times (1:80)

and still reacted you knew there must be more antibody than if the

serum stopped demonstrating a reaction at 1:40. In autoimmune

diseases you might have a titer as high as 1:1280, so much antibody

that even after diluting it over 1000 times there was still enough to

react to the antigen. Somewhere along the line they must have

actually measured the amount of antibody not just the dilution and

now express it in an absolute amount, e.g. in units, mcg, or mg.

The important fact to take home is a single measured titer only tells

you at sometime in that persons life they were exposed to that

antigen which made the antibody, not when it happen or if that titer

is going up or down. In strep infections the strep antigen make anti-

strep antibodies called ASO, a positive ASO does not tell you if you

have an active infection only that a sometime there was strep around.

If you follow serial titers you get a feel how active the process is,

going up probablely implies and active or recent exposure, going down

more distant. For immunizations the CDC probablely has a titer they

feel is protective and a level they feel is not, for our purposes,

for us that think these antibodies are causing harm as well as being

protective, the higher the count the more likely the antibodies are

doing something bad. This a simplified explanation with multiple hole

or exceptions but I think you all get the basic idea, hope this helps-

-- In , " ctlamont " <psychmjr@m...>

wrote:

> They just tested my daughter. Apparently the measles and mumps

were

> around 2.2 and 2.4 - but her Rubella came back 152. Any thoughts?

> Thanks

> (mom to Kait asd & nt 28 months)

> psychmjr@m...

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Regarding MMR titers, my son is now 12. We did titers when he was 3. His

rubella titers were through the roof, measles was at expected levels, and he

had no mumps titers. Another child who responded to IVIG had a similar

profile but my son did not respond as well to it. After secretin infusions

his rubella titer dropped and has remained relatively low however secretin

effects were temporary. I suspect that these titers indicate that the immune

system is functioning abnormally, overreacting to some antigens and not at

all to others. Whether this is associated with actual infections or

autoimmunity is unclear however the improvements with valtrex suggest an

infection which may also be related to autoantibody formation. Clearly the

immune system of some 15 month olds is not meant to receive an MMR vaccine.

It would be worthwhile to compare MMR responses in autistic kids versus

" normal kids " to see if these abnormalities occur more significantly. For

those who had titers done on MMR, what patterns were present? Is the high

rubella, low or absent measles/mumps pattern a common one? This evidence

might be useful in understanding what is going on in autism. We need to know

if this pattern is different from what is expected.

Ken Sokolski

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Hi,

We had MMR titers done on my daughter who is diagnosed HFA and has

whose hair test met the counting rules for mercury toxicity. The

measles and mumps reports just say " positive - see text " which we

didn't get. The mumps says 128 with no reference range. These were

done at 5 y 2 m. I assume that 128 is very high.

So, my daughter does not fit the same profile as your child.

BTW, despite having the chicken pox vaccine, my daughter has just come

down with a pretty significant case of it. I don't know if that

indicates some abnormality in reaction to viruses. Other kids in her

class who'd had the vaccine got very mild cases.

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