Guest guest Posted September 13, 2005 Report Share Posted September 13, 2005 Hi all A couple of weeks ago, I had gone in for an ERCP to determine if I had PSC, but there was a twist in my bile duct, so the doctor was unable to finish off the procedure. What he ended up doing was making a cut in the twist, so he could go in at the end of the month to finish off the procedure. Then last week I had gone into the hospital because the area around my liver was feeling a little bit tender and I had a little bit of a fever, and I just wanted to make sure that there was nothing wrong, as I will be getting married next weekend and I didn't want to be sick for the wedding. During the testing, they said my liver enzymes had gone back to normal levels, from being four to five times their normal levels. Is this common? Of course, I may be grasping at straws hoping that I don't have PSC, but is it common to have twists in a bile duct which could have been causing a blockage and thus increasing my enzyme levels? And can just putting a cut in the bile duct reduce the enzyme level? Terry UC 90 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 13, 2005 Report Share Posted September 13, 2005 Hello Terry; I've not heard of a " bile duct twist " before, but I could imagine that if one occurred, it might block bile flow from the liver and result in elevated serum liver enzyme levels. Bile duct ligation (creating a bile duct blockage) in laboratory animals is often used to induce cholestasis, and study the effects of cholestasis on liver biochemistry, including elevated LFTs. So, if this " twist " was the cause of your elevated LFTs and bile flow was restored by the surgical procedure [but I'm not sure exactly how the " cut " would unblock the twist ... you'll have to ask your surgeon to explain this], your LFTs would tend to return to normal. Let's hope that this was the sole cause of your elevated LFTs and that a subsequent ERCP does not show PSC. Have a great wedding this weekend! Congratulations! Best regards, Dave (father of (20); PSC 07/03; UC 08/03) Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 13, 2005 Report Share Posted September 13, 2005 wrote: > I've not heard of a " bile duct twist " before, but I could imagine that > if one occurred, it might block bile flow from the liver and result in > elevated serum liver enzyme levels. When I had an ERCP in 2001 (for PSC diagnosis and stent placement), the drs. said my main duct was so severely sclerosed and fibrotic (due to the PSC being already so far advanced) that it had become " corkscrewed " thus making it impossible to get the stent in place. They immediately sent me to MUSC and Dr, Cotton got the stent inserted. Whether or not Terry's " bile duct twist " is the same as my " corkscrewed duct " is debatable. Terry might simply have a torsion or some other mild anomaly. I honestly hadn't even thought about whether the " corkscrew " effect is typical or not. I would think, though that if you haven't come across it in all your vast research, it must not be very common. Regards, Carolyn B. in SC Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 17, 2005 Report Share Posted September 17, 2005 Terry You got great questions. I have only 1 reply. PSC is a chronic disease. It flares and remits, so lab fluctuations are the norm. Congrads on the neptuals. Bestjd, 45UC 1973, Jpouch 2000, Chronic Pouchitis 2001, PSC 2004, Stage 3Southern, ILkrmpotich@... ----- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 21, 2005 Report Share Posted September 21, 2005 So is it quite common for the results to change as listed below, with pre procedure blood tests and then post procedure blood tests ALP 643 139 AST 137 21 GGT 547 108 ALT 156 37 By the way, the wedding was amazing, my wife (still sounds weird saying it), has never looked so beautiful. With her kidney disease and my potential liver disease, I think we were the only two sober people there. But it was still fun. Terry UC 90 Re: Liver enzymes Terry You got great questions. I have only 1 reply. PSC is a chronic disease. It flares and remits, so lab fluctuations are the norm. Congrads on the neptuals. Bestjd, 45UC 1973, Jpouch 2000, Chronic Pouchitis 2001, PSC 2004, Stage 3Southern, ILkrmpotich@... ----- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 21, 2005 Report Share Posted September 21, 2005 Congratulations on your wedding!!!LeeSo is it quite common for the results to change as listed below, with pre procedure blood tests and then post procedure blood tests ALP   643   139AST   137   21GGT   547   108ALT   156   37 By the way, the wedding was amazing, my wife (still sounds weird saying it), has never looked so beautiful. With her kidney disease and my potential liver disease, I think we were the only two sober people there. But it was still fun. TerryUC 90 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 21, 2005 Report Share Posted September 21, 2005 Which procedure? An ERCP with balloon dilatation and stenting might account for it. Arne54 - UC 9/77 - PSC 4/00Alive and (mostly) well in Minnesota From: [mailto: ] On Behalf Of Terry Craig So is it quite common for the results to change as listed below, with pre procedure blood tests and then post procedure blood tests ALP 643 139 AST 137 21 GGT 547 108 ALT 156 37 By the way, the wedding was amazing, my wife (still sounds weird saying it), has never looked so beautiful. With her kidney disease and my potential liver disease, I think we were the only two sober people there. But it was still fun. Terry UC 90 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 21, 2005 Report Share Posted September 21, 2005 The doctor had put a cut into the bile duct because he was unable to complete the ERCP due to a twist in the bile duct. The cut was being done to straighten out the bile duct. It was after putting this cut in that the liver enzymes went down. He will be completing the ERCP on the 29th. Terry UC 00 RE: Liver enzymes Which procedure? An ERCP with balloon dilatation and stenting might account for it. Arne54 - UC 9/77 - PSC 4/00Alive and (mostly) well in Minnesota From: [mailto: ] On Behalf Of Terry Craig So is it quite common for the results to change as listed below, with pre procedure blood tests and then post procedure blood tests ALP 643 139 AST 137 21 GGT 547 108 ALT 156 37 By the way, the wedding was amazing, my wife (still sounds weird saying it), has never looked so beautiful. With her kidney disease and my potential liver disease, I think we were the only two sober people there. But it was still fun. Terry UC 90 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 22, 2005 Report Share Posted September 22, 2005 Terry Yep. Mine have looked very similar over the past year and that is without any special measures such as experimental drugs. If those on the right hand side are more recent, at least your headed in a positive direction. (me too). Certainly know the bride beauty experience. My bride was the same. it's been 10 years and we "dated" for about 5 before that. On the big day I was so taken by her radiance that I choked back a flood of tears through a significant part of the nuptials. I thought that by then I'd seen her at her best (and worst), but alas, I was wrong. Sort of like love, just when you think you have arrived, it deepens. Enjoy married life. It's the best. Bestjd, 45UC 1973, Jpouch 2000, Chronic Pouchitis 2001, PSC 2004, Stage 3Southern, ILkrmpotich@... Re: Liver enzymes Terry You got great questions. I have only 1 reply. PSC is a chronic disease. It flares and remits, so lab fluctuations are the norm. Congrads on the neptuals. Bestjd, 45UC 1973, Jpouch 2000, Chronic Pouchitis 2001, PSC 2004, Stage 3Southern, ILkrmpotich@... ----- Quote Link to comment Share on other sites More sharing options...
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