Re: GENETICS

[Guest guest]

In a message dated 8/10/2004 5:01:18 PM Eastern Daylight Time, j.vdijk@...

writes:

The CHD7-gene belongs to the well known family of regulation genes,

which functions as a kind of relay panel in switching on/off of other

genes. A defect of this process lead to problems in the early

embryological development. This explains why many organ systems are

involved in Chare Syndrome.

Hello,

Is there a way that families can be checked for these findings

now? I would really like to know what my son's show. He is now 20 and it has

been a lond haul.

[Guest guest]

In a message dated 8/10/2004 10:50:13 PM Eastern Standard Time,

klauger@... writes:

Everything we describe with the " behaviors " and

fluctuating states, hyper one day and unable to move the next, indicate

difficulty with communication across the synapses.

I'm actually reading The Out of Sync Child in reference to myself and my

non-CHARGE kid right now. From reading that and some other sensory integration

stuff, it certainly seems like many of the systems obviously affected by CHARGE

are very closely tied to sensory integration. Which in turn leads to all kinds

of behavior stuff, including " inconsistency " which according to this author is

a trademark of neurological disfunction. In the book, the author mentions

many possible causes for DSI, including birth trauma/prematurity, genetics, and

surgeries. With everything that CHARGErs go through, it seems like anyone of

tem not born with sensory/regulatory problems would end up with some! Has anyone

else read this book? Or the sequel?

[Guest guest]

In a message dated 8/10/2004 10:50:13 PM Eastern Standard Time,

klauger@... writes:

Everything we describe with the " behaviors " and

fluctuating states, hyper one day and unable to move the next, indicate

difficulty with communication across the synapses.

I'm actually reading The Out of Sync Child in reference to myself and my

non-CHARGE kid right now. From reading that and some other sensory integration

stuff, it certainly seems like many of the systems obviously affected by CHARGE

are very closely tied to sensory integration. Which in turn leads to all kinds

of behavior stuff, including " inconsistency " which according to this author is

a trademark of neurological disfunction. In the book, the author mentions

many possible causes for DSI, including birth trauma/prematurity, genetics, and

surgeries. With everything that CHARGErs go through, it seems like anyone of

tem not born with sensory/regulatory problems would end up with some! Has anyone

else read this book? Or the sequel?

[Guest guest]

In a message dated 8/10/2004 10:50:13 PM Eastern Standard Time,

klauger@... writes:

Everything we describe with the " behaviors " and

fluctuating states, hyper one day and unable to move the next, indicate

difficulty with communication across the synapses.

I'm actually reading The Out of Sync Child in reference to myself and my

non-CHARGE kid right now. From reading that and some other sensory integration

stuff, it certainly seems like many of the systems obviously affected by CHARGE

are very closely tied to sensory integration. Which in turn leads to all kinds

of behavior stuff, including " inconsistency " which according to this author is

a trademark of neurological disfunction. In the book, the author mentions

many possible causes for DSI, including birth trauma/prematurity, genetics, and

surgeries. With everything that CHARGErs go through, it seems like anyone of

tem not born with sensory/regulatory problems would end up with some! Has anyone

else read this book? Or the sequel?