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Question about Metformin

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Someone asked:

" Is there any truth at all to the rumor that Metformin destroys the lining

of

one's kidneys? "

Idid a search of the research literature and the web in general.

The short answer is no, what I found agrees with this link .

http://www.healthcentral.com/diabetes/c/5068/27271/metformin-kidneys

" The drug metformin is not recommended for people with kidney disease. For

this reason, some people think that metformin causes kidney disease. But

new evidence suggests that metformin might actually protect the kidneys. "

Here is a longer explanation.

Metformin is cleared by the kidnies. That means over time it is filtered

out by them. If one has serious kidney disease the level of metformincan

stay high for long periods of time because the filtering doesn't work as

normal . Too much metformin that could result from this buildup can cause

a rare disorder called lactic acidosis.

Metformin in general however helps prevent damage in many kinds of tissue,

including some conditions which might harmnormal kidnies.

It has been in use for at least 25 years here and abroad and is considered

a very safe drug.

XB

IC|XC

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