Guest guest Posted December 30, 2003 Report Share Posted December 30, 2003 As I was confused myself, I researched these products. Both work by adsorbing water in the blood thus concentrating the formed elements (platelets) and clotting proteins. This activates and hastens the clotting cascade through hemoconcentration. One does so through a physical reaction and the other does so through simple water adsorption. QuikClot: QuikClot's main component material is a synthetic derivative of volcanic rock. It has many pores that capture and hold the water molecules in the blood. The ability to attract and hold the water molecules is due to electrostatic forces that are present in the pores of QuikClot material when it is dry and are liberated when the QuikClot is saturated. These are the same types of forces that cause static cling, but in the formulation of QuikClot, they are much stronger. Water molecules are held very strongly. The clotting factors, proteins in the blood, and the cellular components of the blood are not attracted nor held by the QuikClot, because they are simply too big to fit in the pore structure of the QuikClot material. This leaves them free to do their work at the wound site. Upon application, QuikClot rapidly attracts water molecules, and almost instantly the internal pores are filled. There are no chemical changes to the blood, the water, or the QuikClot. Since the reaction is physical, and not biological or chemical, there is almost no chance for an allergic reaction to occur. The adsorption of water into the QuikClot granules can cause an instantaneous release of heat, called an exothermic reaction. The release of heat stops when the pores of the QuikClot become filled, which due to QuikClot's strong attraction for water, is only a second or two. There are many variables that affect the heat generated when QuikClot is used. It's been our experience that the exothermic reaction with blood generates less heat than water alone. Under controlled experiment conditions, the highest temperature observed was 140 degrees F. Cost is about $ 22.00 per application. TRaumaDEX: Starch-based beads are placed in powder form. These have a large osmotic action dehydrating the blood and concentrating the formed elements and clotting factors. No exothermic reaction occurs. No evidence of allergic reaction, Cost is $10.95 per application. The only study shows TraumaDEX no more effective than bandaging, but shows QuikClot to be more effective. This is probably because it has more electrostatic properties and there may be some benefit from the exothermic reaction. The studies on the TraumaDEX web site are simply anecdotal videos that look impressive, but tell us nothing about outcome. I see no benefit from either of these in EMS except as part of a disaster pack for an MCI. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 30, 2003 Report Share Posted December 30, 2003 Did they give a cost factor for Quick-Clot? As I stated before, the cost for TraumaDex is extremely high and show no reason for use. Andy Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 30, 2003 Report Share Posted December 30, 2003 Disregard last post. I see it in the last paragraph. I was scanning through too fast. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 30, 2003 Report Share Posted December 30, 2003 Disregard last post. I see it in the last paragraph. I was scanning through too fast. Quote Link to comment Share on other sites More sharing options...
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