Guest guest Posted November 4, 2003 Report Share Posted November 4, 2003 Following is more information received from my niece who is a physician (geneticist) regarding genes and IgaN. Jack (NY) A site I use very often for genetics work is called OMIM. it has a summary of genetic info on IgA nephr at: http://www.ncbi.nlm.nih.gov/htbin-post/Omim/dispmim?161950. McKusick, who edits the site, just summarizes pertinent articles with little other explanation. He does mention some recent work on trying to find a gene associated with the disease, but it seems none has yet been found. There could be different genes acting in different patients/families. It seems to me that it is similar to some of the autoimmune diseases such as rheumatoid arthritis for which there could be a familial increased risk but no clear cut familial inheritance pattern. Hope we learn more about this in the near future, especially for treatment purposes. (btw - I don't know anything about using a gluten free diet for this, and the fact that he only mentioned one article discussing it makes me think it wasn't pursued by a lot of other researchers.) we should keep looking at the genetic sites periodically since things change so quickly in this field! Quote Link to comment Share on other sites More sharing options...
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