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Re: Ascorbic Acid & Sugar

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Excellent read!, I wish I could get all diabetics and non-diabetics to

believe it. Take that B6, and even better yet take a B complex vitamin

tablet every day from now on.

Ascorbic Acid & Sugar

> ASCORBIC ACID COMPETES WITH SUGAR IN THE IMMUNE SYSTEM

> http://www.newswithviews.com/Howenstine/james52.htm

>

> By Dr. Howenstine, MD.

> December 25, 2006

> NewsWithViews.com

>

> Nearly every animal converts sugar into ascorbic acid (Vitamin C). Human

> beings, primates and guinea pigs are the only organisms unable to do this.

> The

> enzyme L-gulonolactone oxidase that accomplishes this chemical reaction

> does

> not work in these beings. This forces these beings to obtain ascorbic acid

> from food or supplements. Research studies suggest that humans would

> produce

> about 2 to 4 grams of Vitamin C daily under normal conditions and about 15

> grams daily

> [1]

> when under stress.

>

> Insulin moves both glucose and ascorbic acid into cells including

> phagocytic

> immune cells. The phagocytic cells like leukocytes attack and remove

> microbes,

> tumor cells and debris from the blood. The level of ascorbic acid in

> leukocytes may be 80 times greater than that found in plasma. Glucose and

> ascorbic

> acid are constantly competing for insulin transport so diets high in sugar

> and carbohydrates will decrease the amount of ascorbic acid that enters

> cells

> and thus create undesirable effects on the immune response.

>

> There is another form of competition between glucose and ascorbic acid.

> Ascorbic acid stimulates the hexose monophosphate (HMP) shunt and glucose

> inhibits

> it. The HMP is a series of chemical reactions that reduces niacin coenzyme

> NADP to NADPH. Phagocytes need NADPH to create superoxide and other

> reactive

> oxygen species that are used to destroy pathogens. In addition to creating

> NADPH ascorbic acid has the ability to deactivate excess quantities of

> NADPH

> and oxidative substances that could harm normal tissues.

>

> The hexose monophosphate shunt also produces 5 carbon sugars (ribose and

> deoxyribose). These 5 carbon sugars are needed to make DNA and RNA. When

> the

> immune

> system faces microbial invasion it immediately signals for production of

> new

> immune cells that need these genetic materials DNA and RNA. If the body

> has

> too much glucose and too little ascorbic acid there will be a lack of

> genetic material and inadequate DNA and RNA for creation of needed new

> leukocytes.

> Clearly high sugar intake will reduce the potential health benefits of

> this

> pathway.

>

> The failure to evaluate glucose intake may afford a good explanation for

> failure of some earlier research studies about ascorbic acid to show

> beneficial

> effects. Persons taking Vitamin C with sugary fruit drinks and pastries

> will

> fail to show any benefit from Vitamin C therapy.

>

> The addictive property of sugar makes it routine for food manufacturers to

> place sugar in nearly all packaged and processed foods. Sugar intake in

> U.S.

> citizens has gone from a few pounds a year in 1800 to about 155 pounds per

> person currently. The excess intake of sugar plays a major role in the

> current

> diabetic epidemic, obesity, arteriosclerosis and rising cancer incidence.

>

> A Swedish urologist, Dr. Jan Hammarsten, is an expert in the relationship

> between insulin and prostate cancer.

> [2]

> He relates that there is no evidence that insulin causes prostate cancer.

> What insulin does do is act as a stimulus for prostate and probably other

> cancers

> to grow and become more aggressive. Between the years 1995 and 2003 Dr.

> Hammarston's group studied 320 patients with biopsy proven prostate

> cancer.

> They

> also used ultrasound to measure the size of the prostate gland. They did

> blood tests for all the components of metabolic syndrome (insulin,

> cholesterol,

> triglycerides and uric acid).

>

> Excess insulin caused the cancers to grow more rapidly. The men who died

> had

> a faster rate of growth of prostate tissue and also had more aggressive

> scores

> on the cancer biopsy samples. Elevated fasting blood insulin levels were

> associated with the lethal cases of prostate cancer. The higher the

> insulin

> levels

> the greater the likelihood of death. The insulin values were more accurate

> than microscopic grading of stage of the tumor or PSA values in

> identifying

> persons at risk of rapid fatal cancer courses. This suggests that revising

> diets in cancer patients toward low insulin stimulating foods may be as

> worthwhile

> as what therapeutic agents are being administered.

>

> Excessive sugar intake is now regarded as the number one risk factor for

> females

> [3]

> and the number two risk factor for males in the causation of heart

> attacks.

> Obviously public health efforts to decrease arteriosclerotic heart disease

> should focus on this problem. However, the truth about sugar could hurt

> food

> conglomerate profits so it is not discussed. Pyridoxine B6 100 mg daily

> significantly

> decreases the incidence of heart attacks probably by the mechanism of it's

> infection

> [4]

> fighting capability. Decrease in gingivitis and bacterial infection in

> artery walls can curb the incidence of arteriosclerosis.

>

> There is evidence that the Vitamin Pyridoxin B6 appears to block the

> adverse

> effects of excessive intake of glucose in patients with arteriosclerosis

> as

> use of this vitamin decreased death from heart attacks in population

> [5]

> studies involving women.

>

> Supplemental Vitamin B6 also increases the possibility of avoiding cancer.

> [6]

> Therefore all persons may benefit from taking 100 mg of B6 Pyridoxine

> daily.

>

> What happens to patients who lower their insulin values? Dr. Dean Ornish

> uses a plant based diet. The cancer markers for the men on this diet

> decreased

> [7]

> over a one year followup whereas the control patients on a standard diet

> saw their tumor markers get worse. This suggests that individuals on a low

> fat

> low carbohydrate diet will do well in avoiding and defeating cancer by

> keeping their insulin values low. This diet is exactly the same as the

> diet

> used

> in the initial stage of therapy for Type 2 diabetes.

> [8]

>

> Dr. Rowen advises getting an 8 hour fasting insulin test annually

> which is a good idea because it identifies persons at risk of becoming

> diabetics

> when elevated values are discovered. This test may be even more important

> for patients with malignancies because elevated insulin results select out

> the

> cancer patients at risk of early death because of rapid uncontrolled

> spread

> of cancer. Persons with or concerned about cancer will probably fare

> better

> if they go on a low fat, low carbohydrate diet. The fasting insulin value

> needs to be below 5 mU/L.

> [9]

> The nearer this value is to zero the better. On a vegetarian low fat low

> carbohydrate diet Dr. Rowen has been able to reduce his fasting insulin

> blood

> level to zero. Decreasing fat intake in the diet permits smaller

> quantities

> of insulin to control blood sugar values than when fat intake is

> uncontrolled.

> When there is no carbohydrate excess in the diet and the carbohydrates

> being

> eaten are low glycemic (do not cause prompt large increases in insulin

> output)

> the pancreas produces less or no insulin. High glycemic carbohydrates

> include potatoes, corn, rice, bananas and pasta.

>

> images/Article-Support-NWV

>

> To the best of my knowledge no other cancers have yet been studied to see

> if

> this relationship between high carbohydrate diet with corresponding high

> insulin

> levels causes increasing cancer deaths holds up for other cancers as well.

> My guess is this is likely to turn out to be just as dangerous for these

> cancers

> as it is for prostate cancer.

>

> images/Free-Alerts

>

> The fasting insulin blood test is probably the most important blood test

> that is rarely utilized by U.S. health care providers. Insist on obtaining

> this

> test at least once a year. Early discovery of high insulin values enables

> the pre Type 2 diabetic to institute restriction of sugar and fat which

> will

> reverse the impending diabetic state in 90 % of persons. This will permit

> these individuals to avoid the ravages of long term hyperinsulinemia

> (premature

> aging and death).

>

> Footnotes:

>

> #_ftnref1

> 1, Ottoboni F. Ottoboni A. Ascorbic acid and the immune system. The

> Journal

> of Orthomolecular Medicine 2005;20(3):179-183

> #_ftnref2

> 2, Hyperinsulinemia: a prospective Risk Factor for Lethal Clinical

> Prostate

> Cancer Eur J. Cancer, 2005 Dec; 41(18):2887-95 EPub 2005,October 20.44412

> (5/2006);

> #_ftnref3

> 3, Grant WB Reassessing the role of sugar in the etiology of heart

> disease.

> J Orthomolecular Med 1998;13(2): 95-104

> #_ftnref4

> 4, LS et al Vitamin B6 and immune competence Nutrition Reviews 1993;51,

> 8:217-25

> #_ftnref5

> 5, Rimm EB et al Folate and vitamin B6 from diet and supplements in

> relation

> to the risk of coronary heart disease among women Journal American Medical

> Assoc 1998; 279:5:359-364

> #_ftnref6

> 6, Maksymowych AB et all Efficacy of Pyridoxal treatment in controlling

> the

> growth of melanomas in cell cultures and an animal pilot study. Anticancer

> Research

> 1993; 13: 1925-1938

> #_ftnref7

> 7, Ornish, Dean et al J. Urol.. 2005; 174(3) 1065-9

> #_ftnref8

> 8, Howenstine, A. A Physicians Guide To Natural Health Products That

> Work 2002 pg. 100-04 Penhurst Books Miami, Fl.

> #_ftnref9

> 9,

> Global/story

> Rowen, M.D. Second Opinion Vol XVI No. 11 November pg 1-3.

>

> © 2006 Dr. Howenstine - All Rights Reserved

>

> Sign Up For Free E-Mail Alerts

>

> E-Mails are used strictly for NWVs alerts, not for sale

>

--------------------------------------------------------------------------------

>

> Dr. A. Howenstine is a board certified specialist in internal

> medicine

> who cared for office and hospital patients for 34 years. Four years of

> research

> into natural health convinced him that natural products are safer, more

> effective and generally less expensive than pharmaceutical drugs. This

> research

> culminated in writing the book A Physician's Guide To Natural Health

> Products That Work (328 pages) $17.95.

>

> This book and recommended products can be obtained from

> www.naturalheathteam.com

> and by phoning 1-. Dr. Howenstine can be reached at

> dr.jimhow@... and by writing Dr. Howenstine C/O Remarsa USA SB

> 37, P.O. Box

> 25292, Miami, Fl. 33102-5292.

>

> E-Mail:

> dr.jimhow@...

>

>

--------------------------------------------------------------------------------

>

> Home

>

> Glucose and ascorbic acid are constantly competing for insulin transport

> so

> diets high in sugar and carbohydrates will decrease the amount of ascorbic

> acid that enters cells and thus create undesirable effects on the immune

> response.

>

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