New Pain Relief

[Guest guest]

anybody receive a new type of powerful painkiller PELIXIA SR

 

this is a dual-acting painkiller wich doctors say has fewer side effects than

drugs currently available

 

strong pain killers such as morphine contain opioids but side effects of opiods

include vomiting and constipation and often result in patients stopping their

medication

 

the treatment costs gbp 1.87/usd 3.20 a day and is available now

 

it reduces two types of pain: tissue pain[felt when you cut yourself, for

instance] and neuro pain due to nerve damage [buring sensation or electric

shock]

 

any feedback grateful as understand NHS approved [uk]

 

regards/peter/london/ppms

[Guest guest]

hi jim and thanks your reply

 

would appear this drug similar to tramadol and the only place you stick-it is in

your month with water

 

link:

http://worldpainfoundation.org/first-in-class-painkiller-palexia-hits-uk-shores-\

pharma-times.htm

 

brgds/peter

I tell any Dr. at my first appt., not to even mention or suggest any Rx.

medication, that is not available in generic form.They can use them on

themselves as a suppository, but I want nothing to do with them.(Take 'em and

shove 'em, in other words)

This is because any 'new' drug is going throught the final stage of drug

testing, otherwise known as marketing.During the mext 5-10 years, they will find

out all the things they didn't find out, during the approval process, like,...it

rots your liver, gives you heart attacks, causes neuro damage, etc.

And unlike the volonteers, for their pre-approval testing, who at least get PAID

for being guinea pigs, the not only DON'T pay us, they charge us much more, per

pill, for 'new' drugs than for the older established ones.

For chronic pain, I use Codiene, and 'Bioperine', an OTC 'supplement' which

A)shuts off the acid pumps in the stomach, for about an hour, and B)stops the

liver from metabolising, for about 24 hrs.Doesn't HARM the liver, just doesn't

metabolise.Combination of these 2 effects means greatly increased

bioavailability; such that 1/4 of a 15mg codiene, with 5mg. Bioperine, was

eaqual to 15-20mg. of codiene, in terms of pain relief, AND it lasted about

18-24 hrs, when normal dose of codiene would have been metabolised in 4 hrs.

Additional plus's; Bioperine reduces " P " substance, the neurotransmitter which

conveys pain, in a small way.

And, it is a SELECTIVE opiod blocker; it only blocks the respiratory depression

of opiods, while not blocking the pain relief aspects.

Must be used with caution, as effect of stopping metabolism are not limited to

meds/substances its taken with.I couldn't understand why I was having insomnia,

till I realised DOH!, I had drunk my normal 4 cups of coffee in the a.m.

Normally, it would have been metabolised by the liver, by 10:00 at nite.Not when

Bioperine is in your system.

Main downsides of organic opiods like morhine and codiene; short 1/2 life, so

need for multi dosing, potential for O.D. and respiratory depression leading to

death, and constipation.As I am taking with Bioperine, and am therfore taking a

much smaller dose, all of these are either reduced or eliminated.:-) However,

since I have started LDN, am not taking either, hoping it will reduce/eliminate

need for Codiene/Bioperine.Anyway,Thats my take.Jim