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WELCOME JOHN COLE

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Welcome to PLS-FRIENDS...this is probably where you belong! I was dx'd.

with PLS Dec. 1997 at the Mayo Clinic after receiving a " Probable PLS " from

Stanford University prior to going to Mayo Clinic in Rochester, MN. I had

symptoms as early as 1994. I just turned 58 and live in Fremont, California

(40 miles south of San Francisco) and I go to the UCSF ALS Research Center

every 6 months. At my last EMG appointment, I showed minor abnormality in my

lower motor neurons (left thumb) so " technically " I have ALS for purposes of

" qualifying " for ALS research.

My neurologist says minor LMN abnormalities are not unexpected in people who

have PLS.

Doctors often disagree in diagnosis. My husband's aunt (by marriage) was

diagnosed with ALS well over 15 years ago and her symptoms are much milder

than mine and I consider my symtpoms fairly mild. I don't use a cane or

walker but I do hang onto my husband for balance when we're out. I insist

that his aunt doesn't have ALS and she, of course, responds with her doctors

say she does.

We are in the process of fundraising for a Symposium.

(Northwestern University Medical School-Primary Lateral Sclerosis Symposium)

Two eminent neurologists have teamed up to plan a symposium in order for the

neurological community to clinically define Primary Lateral Sclerosis. See

<A

HREF= " http://synapsepls.home.attbi.com/donor.html " >http://synapsepls.home.attbi.\

com/donor.html</A> for more information. Only when

PLS is clinically-defined will we be able to see real research for PLS and

hopefully then a cure.

Welcome again and hope you're in our group for a long time.

Gentner

Fremont, CA

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