abstract /sm and ms in autopsy report

[Guest guest]

J Neurol Sci 2001 Mar 1;184(2):189-96

Multiple sclerosis with secondary syringomyelia. An autopsy report.

yet another ms and sm abstract of a report just published ...this is clearly

being found more often now , with three reports just this year ..thought it

might intrest some others .

sarah in paradise

Matsuda M, Tabata K, Miki J, Ishigame H, Asano M, Ikeda S

Department of Neurology, Saku Central Hospital, 197 Usuda, Minamisaku,

384-0393, Nagano, Japan

[Medline record in process]

We report an elderly woman with multiple sclerosis who showed an extensive

cavity formation in the midthoracic cord in addition to multiple abnormal

intensity signals in the central nervous system on magnetic resonance imaging

(MRI). The cavity decreased in size in response to corticosteroid therapy

with an improvement in neurological symptoms. The autopsy demonstrated a

slit-like cavity lined with no ependymal cells on the luminal surface in the

lower cervical to midthoracic cord, with circumferentially distributed

demyelinative lesions, leading to the pathological diagnosis of secondary

syringomyelia. In this patient a limited necrosis formed in the spinal cord

might have developed into a cavity formation with edematous fluid leading to

subsequent episodes of neurological exacerbation.

PMID: 11239955, UI: 21136610