LDN & Allergies

[Guest guest]

I saw a post about the above and thought I'd share with you something from

Dr Tom Gilhooly who does use LDN to treat allergies quite successfully

(apologies for the length of this post):-

This summer has been one of the best for a long time but the good weather

brings with it its own problems. We have had one of the highest pollen

counts in recent years and this has caused misery to millions of those

susceptible to hay fever. My own son was having severe

symptoms particularly itchy, sore eyes which were not helped with eye drops

or anti histamines. It is a shame to have such good sunny weather at the

same time as having

disturbed sleep with hay fever. The next step after anti histamines has

traditionally been steroids either orally or by injection. When my son asked

what other treatment could be tried I

was reluctant to recommend steroids. This seemed like a sledgehammer to

crack a nut and there is always a concern about the side effects of

steroids. The way steroids work is to block an enzyme that is required to

make repair hormones, these can be inflammatory or anti inflammatory

depending on whether they are based on omega 3 or omega 6 fats. This

obviously reduces the inflammation associated with hayfever, but

obliterating the anti inflammatory hormones along the way can cause

significant side effects such as ulcers and

osteoporosis.

One thing that I had noted from my clinic was that patients on LDN were

reporting having very few hay fever symptoms and as this is an immune based

condition it makes sense that it

would work for this. The big advantage over steroids is that LDN is

relatively free of side

effects. It is an immune modulator rather than an immune suppressant, which

reduces the inflammation of the immune system without flattening the whole

system. I decided it would be a safe medication to try and he started it the

next day. In this clinical trial of one, he reported the best night he has

had for weeks and although his symptoms were not completely

gone, it was now bearable. On the second day he informed me that I did not

know the true potential of this drug! Maybe none of us do but we can add

another new condition that seems to respond to LDN. In atopic conditions one

of the main inflammatory cells are the mast cells. The activity of these

cells is controlled by receptors on the surface known as Toll-like

receptors. The recent Stanford University study into LDN in Fibromyalgia

showed that LDN binds to the toll-like 4 receptors which suppress

inflammatory activity. This binding is the probable mode of action in

hayfever, where LDN binds to these receptors and reduces the production of

inflammation. This suggests that LDN may have a potential action in other

atopic conditions such as asthma and eczema.

http://www.ldnresearchtrustfiles.co.uk/docs/August_2010.pdf (page 5)

Jayne Crocker

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Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the

myriad of uses it shows benefit for.

<

Dr Steele MBE, talking

about LDN

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