Re: Lee/ Introduction/Alkaline Phosphatase/Milk Thistle

[Guest guest]

Hello Lee;

I'm very sorry to hear about your son's PSC diagnosis. As Shauna

mentioned earlier, elevated alkaline phosphatase is common in PSC,

and levels tend to fall once patients are placed on ursodeoxycholic

acid (ursodiol).

How old is your son? The " normal " level of alkaline phosphatase level

depends to a large extent on your son's age .... during normal bone

growth, alkaline phosphatase can be elevated about 3 to 5-fold in

teens! This does not seem to be widely recognized!

This point is discussed in detail in the following article:

http://www.nacb.org/lmpg/Hepatic_LMPG_PDF.stm

and specifically the section on:

Guidelines for Performance of Laboratory Tests of Liver Function and

Injury (366 kb)

http://www.nacb.org/lmpg/hepatic/2_hepatic_Guidelines.pdf

(See section on Alkaline Phosphatase: p. 9)

If your son is still actively growing, some of the elevated alkaline

phosphatase could be due to this normal bone growth!

Here's a detailed article on Milk Thistle:

Milk Thistle: Effects on Liver Disease and Cirrhosis and Clinical

Adverse Effects

http://www.ahrq.gov/clinic/epcsums/milktsum.htm

Hope this information helps.

Best regards,

Dave

(father of (19); PSC 07/03; UC 08/03)

P.S. Whereabouts are you located in MI?

> Thank you for your welcome. We are in MI. I am sorry too

that

> your young son also has this disease. I am concerned because there

is

> still so much that we don't know. My son's AlK was 800 on his last

> check when normal high is only 130. Is this typical with PSC? I

would

> also like to know about the Milk Thistle.

> Best wishes for improved health,

> Lee

>

[Guest guest]

Thanks for the reply . We are in Ann Arbor MI. My son is 21 and is

probably done growing. I tried to get to the article but I couldn't

open it. I am on a Mac computer and new to using it for anything other

than email. I will ask my husband to help me open it when he is home.

Thanks again.

Lee

> Hello Lee;

>

> I'm very sorry to hear about your son's PSC diagnosis. As Shauna

> mentioned earlier, elevated alkaline phosphatase is common in PSC,

> and levels tend to fall once patients are placed on ursodeoxycholic

> acid (ursodiol).

>

> How old is your son? The " normal " level of alkaline phosphatase level

> depends to a large extent on your son's age .... during normal bone

> growth, alkaline phosphatase can be elevated about 3 to 5-fold in

> teens! This does not seem to be widely recognized!

>

> This point is discussed in detail in the following article:

>

> http://www.nacb.org/lmpg/Hepatic_LMPG_PDF.stm

>

> and specifically the section on:

>

> Guidelines for Performance of Laboratory Tests of Liver Function and

> Injury (366 kb)

>

> http://www.nacb.org/lmpg/hepatic/2_hepatic_Guidelines.pdf

>

> (See section on Alkaline Phosphatase: p. 9)

>

> If your son is still actively growing, some of the elevated alkaline

> phosphatase could be due to this normal bone growth!

>

> Here's a detailed article on Milk Thistle:

>

> Milk Thistle: Effects on Liver Disease and Cirrhosis and Clinical

> Adverse Effects

>

> http://www.ahrq.gov/clinic/epcsums/milktsum.htm

>

> Hope this information helps.

>

> Best regards,

>

> Dave

>

> (father of (19); PSC 07/03; UC 08/03)

>

> P.S. Whereabouts are you located in MI?

>

>

>> Thank you for your welcome. We are in MI. I am sorry too

> that

>> your young son also has this disease. I am concerned because there

> is

>> still so much that we don't know. My son's AlK was 800 on his last

>> check when normal high is only 130. Is this typical with PSC? I

> would

>> also like to know about the Milk Thistle.

>> Best wishes for improved health,

>> Lee

>>

>

>

>

>

>

>

>

[Guest guest]

Thanks for the reply . We are in Ann Arbor MI. My son is 21 and is

probably done growing. I tried to get to the article but I couldn't

open it. I am on a Mac computer and new to using it for anything other

than email. I will ask my husband to help me open it when he is home.

Thanks again.

Lee

> Hello Lee;

>

> I'm very sorry to hear about your son's PSC diagnosis. As Shauna

> mentioned earlier, elevated alkaline phosphatase is common in PSC,

> and levels tend to fall once patients are placed on ursodeoxycholic

> acid (ursodiol).

>

> How old is your son? The " normal " level of alkaline phosphatase level

> depends to a large extent on your son's age .... during normal bone

> growth, alkaline phosphatase can be elevated about 3 to 5-fold in

> teens! This does not seem to be widely recognized!

>

> This point is discussed in detail in the following article:

>

> http://www.nacb.org/lmpg/Hepatic_LMPG_PDF.stm

>

> and specifically the section on:

>

> Guidelines for Performance of Laboratory Tests of Liver Function and

> Injury (366 kb)

>

> http://www.nacb.org/lmpg/hepatic/2_hepatic_Guidelines.pdf

>

> (See section on Alkaline Phosphatase: p. 9)

>

> If your son is still actively growing, some of the elevated alkaline

> phosphatase could be due to this normal bone growth!

>

> Here's a detailed article on Milk Thistle:

>

> Milk Thistle: Effects on Liver Disease and Cirrhosis and Clinical

> Adverse Effects

>

> http://www.ahrq.gov/clinic/epcsums/milktsum.htm

>

> Hope this information helps.

>

> Best regards,

>

> Dave

>

> (father of (19); PSC 07/03; UC 08/03)

>

> P.S. Whereabouts are you located in MI?

>

>

>> Thank you for your welcome. We are in MI. I am sorry too

> that

>> your young son also has this disease. I am concerned because there

> is

>> still so much that we don't know. My son's AlK was 800 on his last

>> check when normal high is only 130. Is this typical with PSC? I

> would

>> also like to know about the Milk Thistle.

>> Best wishes for improved health,

>> Lee

>>

>

>

>

>

>

>

>