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Re: Hair, TPN

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,

Your situation reminds me of something Jeannine said once about Caitlin and

her steroid dependency. Try telling the doctor the following and see if

she's more open to chelation:

" We can have a short and skinny child that's alive or we can have a tall

dead child - I prefer the former. " I know it sounds harsh, but it might

give her a new perspective.

Good Luck.

Terri

>

>Reply-To: Mitoonelist

>To: Mitoonelist

>Subject: Re: Hair, TPN

>Date: Sun, 19 Dec 1999 15:32:51 -0800

>

>Ken,

> Hi again. It's me, the bother. lol We are trying to get an appointment

>with the metabolic docs at our

>hospital again, hoping that they will have a change of heart when they

>realize that we do have doctors

>with more experience with mito ready and willing to consult on 's

>case. Cross your fingers for us.

>Also, I took your advice and went to a general peds doc to see if she could

>help manage Matt. Looks

>promising right now, thanks for the excellent advice. We're going to L.A.

>to see Dr. Boles in January to

>get Matt's dietary challenges repeated, so we'll have that information

>also.

> On the down side, our hematologist still does not want to chelate Matt,

>even with Dr. Cohen's advice to

>do so. She feels that because chelation causes kids to stop growing, and

> has just come out of a 4

>month period of no growth and no weight gain, that we should still wait for

>him to grow a bit more. It's

>all so confusing to me, but I'm putting my money on Dr. Cohen's advice, for

>obvious reasons. Now the trick

>is to get her to do it, even though she doesn't want to. She also doesn't

>want Matt to get a g-tube, and

>Dr. Cohen also recommended that. She feels that Matt has so much trouble

>with the little amount of formula

>he does take by mouth (about 5 oz. a day), that we would have no luck with

>a g-tube. I proposed to her a

>compromise, like trying an ng-tube and seeing if that helped him before

>putting him through surgery to

>place a g-tube. I'm still waiting for a response on that issue.

>

>

>

>

>Ken Hirsch wrote:

>

> >

> >

> > Zinc deficiency is a well-known cause for brittle, thin hair. Rhys had

> > problems with it and we cautiously supplemented him for a while. It's

>just

> > one of those nutritional things that must be balanced depending on

>anyone's

> > own particular issues (with either fat, carbo, protein - or combination

> > thereof - intolerances.

> >

> > --------

> >

> > ,

> >

> > Hopefully your docs are checking pyruvate and lactate levels to make

>sure

> > that there aren't any SIGNIFICANT abnormalities caused by the TPN. Too

>bad

> > your metabolic docs at the academic center don't want to take charge.

> >

> > Ken

> >

> > > Brought to you by www.imdn.org - an on-line support group for those

>affected by mitochondrial disease.

>

>

>------------------------------------------------------------------------

>Brought to you by www.imdn.org - an on-line support group for those

>affected by mitochondrial disease.

><< text3.html >>

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Ken,

Hi again. It's me, the bother. lol We are trying to get an appointment with

the metabolic docs at our

hospital again, hoping that they will have a change of heart when they realize

that we do have doctors

with more experience with mito ready and willing to consult on 's case.

Cross your fingers for us.

Also, I took your advice and went to a general peds doc to see if she could help

manage Matt. Looks

promising right now, thanks for the excellent advice. We're going to L.A. to see

Dr. Boles in January to

get Matt's dietary challenges repeated, so we'll have that information also.

On the down side, our hematologist still does not want to chelate Matt, even

with Dr. Cohen's advice to

do so. She feels that because chelation causes kids to stop growing, and

has just come out of a 4

month period of no growth and no weight gain, that we should still wait for him

to grow a bit more. It's

all so confusing to me, but I'm putting my money on Dr. Cohen's advice, for

obvious reasons. Now the trick

is to get her to do it, even though she doesn't want to. She also doesn't want

Matt to get a g-tube, and

Dr. Cohen also recommended that. She feels that Matt has so much trouble with

the little amount of formula

he does take by mouth (about 5 oz. a day), that we would have no luck with a

g-tube. I proposed to her a

compromise, like trying an ng-tube and seeing if that helped him before putting

him through surgery to

place a g-tube. I'm still waiting for a response on that issue.

Ken Hirsch wrote:

>

>

> Zinc deficiency is a well-known cause for brittle, thin hair. Rhys had

> problems with it and we cautiously supplemented him for a while. It's just

> one of those nutritional things that must be balanced depending on anyone's

> own particular issues (with either fat, carbo, protein - or combination

> thereof - intolerances.

>

> --------

>

> ,

>

> Hopefully your docs are checking pyruvate and lactate levels to make sure

> that there aren't any SIGNIFICANT abnormalities caused by the TPN. Too bad

> your metabolic docs at the academic center don't want to take charge.

>

> Ken

>

> > Brought to you by www.imdn.org - an on-line support group for those affected

by mitochondrial disease.

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In a message dated 12/20/99 12:41:35 AM Eastern Standard Time,

momalboe@... writes:

<< Try telling the doctor the following and see if

she's more open to chelation:

" We can have a short and skinny child that's alive or we can have a tall

dead child - I prefer the former. " I know it sounds harsh, but it might

give her a new perspective.

>>

-

I just wrote and deleted a post . . . trying to figure out a way to say

delicately that (though I am not a doctor) the heme's point of view doesn't

seem to make sense to me. (And I know by your post that it doesn't to you

either as you say it is all confusing.) What I was struck by is the fact

that even though does not have the toxic iron build up that requires

chelation, he doesn't grow very well (he is the height of a child half his

age) due to his mito problems. Many children with mito have growth

difficulty. Maybe even most children with mito. So, even if you don't

chelate, he may not grow all that well. He may require other intervention in

order to grow (some kids with mito are growth hormone deficient). It seems

to be two almost entirely separate issues . . . with the only overlap being

that perhaps the chelation will exacerbate an already poor situation for

growth. But, the toxicity of the iron seems to be the worse of the rock and

the hard space you guys are stuck between.

I know how very hard it is to keep discussing issues with the docs, and then

going back again to revisit because you disagree . . . I have been there

myself. It is a horrible balancing act . . . you are dependent on these docs

not getting TOO irritated, yet you have to act as your conscience dictates

for your child. What a tremendous responsibility that is. It just seems so

unfair.

I have noticed that you are very talented at communicating clearly without

being confrontational . . . so I bet you are great at that balancing act.

(I, personally, tend to boil under the surface and then start to cry. I hate

it.)

Hope things work out for you guys soon . . .

Kathy C

mom to (age 8, nda) and (age 3, Complex I and III)

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Terri,

My sentiments exactly!! Thank you for backing me up. I don't understand what

her reluctance is for, it

won't matter how much Matt weighs if he is dead. So thank you.

Terri Mason wrote:

>

>

> ,

>

> Your situation reminds me of something Jeannine said once about Caitlin and

> her steroid dependency. Try telling the doctor the following and see if

> she's more open to chelation:

>

> " We can have a short and skinny child that's alive or we can have a tall

> dead child - I prefer the former. " I know it sounds harsh, but it might

> give her a new perspective.

>

> Good Luck.

>

> Terri

>

> >

> >Reply-To: Mitoonelist

> >To: Mitoonelist

> >Subject: Re: Hair, TPN

> >Date: Sun, 19 Dec 1999 15:32:51 -0800

> >

> >Ken,

> > Hi again. It's me, the bother. lol We are trying to get an appointment

> >with the metabolic docs at our

> >hospital again, hoping that they will have a change of heart when they

> >realize that we do have doctors

> >with more experience with mito ready and willing to consult on 's

> >case. Cross your fingers for us.

> >Also, I took your advice and went to a general peds doc to see if she could

> >help manage Matt. Looks

> >promising right now, thanks for the excellent advice. We're going to L.A.

> >to see Dr. Boles in January to

> >get Matt's dietary challenges repeated, so we'll have that information

> >also.

> > On the down side, our hematologist still does not want to chelate Matt,

> >even with Dr. Cohen's advice to

> >do so. She feels that because chelation causes kids to stop growing, and

> > has just come out of a 4

> >month period of no growth and no weight gain, that we should still wait for

> >him to grow a bit more. It's

> >all so confusing to me, but I'm putting my money on Dr. Cohen's advice, for

> >obvious reasons. Now the trick

> >is to get her to do it, even though she doesn't want to. She also doesn't

> >want Matt to get a g-tube, and

> >Dr. Cohen also recommended that. She feels that Matt has so much trouble

> >with the little amount of formula

> >he does take by mouth (about 5 oz. a day), that we would have no luck with

> >a g-tube. I proposed to her a

> >compromise, like trying an ng-tube and seeing if that helped him before

> >putting him through surgery to

> >place a g-tube. I'm still waiting for a response on that issue.

> >

> >

> >

> >

> >Ken Hirsch wrote:

> >

> > >

> > >

> > > Zinc deficiency is a well-known cause for brittle, thin hair. Rhys had

> > > problems with it and we cautiously supplemented him for a while. It's

> >just

> > > one of those nutritional things that must be balanced depending on

> >anyone's

> > > own particular issues (with either fat, carbo, protein - or combination

> > > thereof - intolerances.

> > >

> > > --------

> > >

> > > ,

> > >

> > > Hopefully your docs are checking pyruvate and lactate levels to make

> >sure

> > > that there aren't any SIGNIFICANT abnormalities caused by the TPN. Too

> >bad

> > > your metabolic docs at the academic center don't want to take charge.

> > >

> > > Ken

> > >

> > > > Brought to you by www.imdn.org - an on-line support group for those

> >affected by mitochondrial disease.

> >

> >

> >------------------------------------------------------------------------

> >Brought to you by www.imdn.org - an on-line support group for those

> >affected by mitochondrial disease.

> ><< text3.html >>

>

> > Brought to you by www.imdn.org - an on-line support group for those affected

by mitochondrial disease.

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Share on other sites

> On the down side, our hematologist still does not want to chelate Matt,

> even with Dr. Cohen's advice to do so. She feels that because chelation causes

kids to stop growing, and

> has just come out of a 4 month period of no growth and no weight gain,

that we should still wait

> for him to grow a bit more.

, has anyone considered the fact that kids don't grow when they are

chronically ill and stressed and

that chelating him may well eliminate one of the major stresses in his life and

" allow " him to grow. This

is something that we have seen time and time again with Caitlin.

Also, I really have to wonder what the accumulation of the iron is doing to his

mito disease state, not to

mention brain cells, as there is already quite a bit of research documenting the

ill effects of the

accumulation of metals on mitochondrial function. The worse shape he is in

metabolically the less he is

likely to grow. And while we're on the subject, has the doctor considered the

possibility that perhaps

the reason he hasn't grown for the past 4 months is that he " needs " the

chelation and the accumulation of

the iron is interfering with his growth.

If it were me, I'd either push really hard, or get another opinion. Our kids

don't always go by the

rules, and many times with mitochondrial disease, it takes a doc that is willing

to look outside the box,

so to speak. It's been our experience that going strictly by the books has

nearly cost us Caitlin's life.

Jeannine

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Kathy,

Thanks for your input. I, too, would rather have alive in whatever

form that may be, than to

have him die from iron toxicity. As hard as Matt has fought for the last year,

it seems so silly to have

something that we can change or prevent do damage to his health. There is so

much about mito and Pearson's

that we don't know, it is such a shame to waste what information we do have.

Thanks again!!

, mommy to

Adrienne 7, Grace 2, and 1 on Thursday (Pearson's Syndrome)

KCorley309@... wrote:

> From: KCorley309@...

>

> In a message dated 12/20/99 12:41:35 AM Eastern Standard Time,

> momalboe@... writes:

>

> << Try telling the doctor the following and see if

> she's more open to chelation:

>

> " We can have a short and skinny child that's alive or we can have a tall

> dead child - I prefer the former. " I know it sounds harsh, but it might

> give her a new perspective.

> >>

>

> -

>

> I just wrote and deleted a post . . . trying to figure out a way to say

> delicately that (though I am not a doctor) the heme's point of view doesn't

> seem to make sense to me. (And I know by your post that it doesn't to you

> either as you say it is all confusing.) What I was struck by is the fact

> that even though does not have the toxic iron build up that requires

> chelation, he doesn't grow very well (he is the height of a child half his

> age) due to his mito problems. Many children with mito have growth

> difficulty. Maybe even most children with mito. So, even if you don't

> chelate, he may not grow all that well. He may require other intervention in

> order to grow (some kids with mito are growth hormone deficient). It seems

> to be two almost entirely separate issues . . . with the only overlap being

> that perhaps the chelation will exacerbate an already poor situation for

> growth. But, the toxicity of the iron seems to be the worse of the rock and

> the hard space you guys are stuck between.

>

> I know how very hard it is to keep discussing issues with the docs, and then

> going back again to revisit because you disagree . . . I have been there

> myself. It is a horrible balancing act . . . you are dependent on these docs

> not getting TOO irritated, yet you have to act as your conscience dictates

> for your child. What a tremendous responsibility that is. It just seems so

> unfair.

>

> I have noticed that you are very talented at communicating clearly without

> being confrontational . . . so I bet you are great at that balancing act.

> (I, personally, tend to boil under the surface and then start to cry. I hate

> it.)

>

> Hope things work out for you guys soon . . .

>

> Kathy C

> mom to (age 8, nda) and (age 3, Complex I and III)

>

> > Brought to you by www.imdn.org - an on-line support group for those affected

by mitochondrial disease.

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this reminds me of something said at our care conference Friday. the docs

were trying to explain to me why they are reluctant to start uridine on the

kids since it is experimental. Finally the VP says to me, " Anne, do you not

understand that there could be a bad outcome if we try this? " I looked at

him and said " do you not understand that there WILL b a bad outcome if we

do not try this " .

They're going to go for it now. They just kill me with their tunnel

vision sometimes.

Anne - home now!!!!!!

----------

>

>

> Terri,

> My sentiments exactly!! Thank you for backing me up. I don't understand

what her reluctance is for, it

> won't matter how much Matt weighs if he is dead. So thank you.

>

>

>

>

> >

> > " We can have a short and skinny child that's alive or we can have a

tall

> > dead child - I prefer the former. " I know it sounds harsh, but it

might

> > give her a new perspective.

> >

> > Good Luck.

> >

> > Terri

>

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Hi Anne. Have you heard anything about your mtDNA tests?? Just wondering how all

of that turned out. Yeah

for you for finally getting somewhere. Best of luck with the uridine, I truly

hope it turns out well for

you. Just incidentally, do you mind if I ask what exactly your doc told you

about Pearson's?

Thanks.

Juhlmann wrote:

>

>

> this reminds me of something said at our care conference Friday. the docs

> were trying to explain to me why they are reluctant to start uridine on the

> kids since it is experimental. Finally the VP says to me, " Anne, do you not

> understand that there could be a bad outcome if we try this? " I looked at

> him and said " do you not understand that there WILL b a bad outcome if we

> do not try this " .

>

> They're going to go for it now. They just kill me with their tunnel

> vision sometimes.

>

> Anne - home now!!!!!!

>

> ----------

> >

> >

> > Terri,

> > My sentiments exactly!! Thank you for backing me up. I don't understand

> what her reluctance is for, it

> > won't matter how much Matt weighs if he is dead. So thank you.

> >

> >

> >

> >

> > >

> > > " We can have a short and skinny child that's alive or we can have a

> tall

> > > dead child - I prefer the former. " I know it sounds harsh, but it

> might

> > > give her a new perspective.

> > >

> > > Good Luck.

> > >

> > > Terri

> >

>

> > Brought to you by www.imdn.org - an on-line support group for those affected

by mitochondrial disease.

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