Second-Line Antiretroviral Drugs: Report of a WHO Working Group Meeting

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Prioritizing Second-Line Antiretroviral Drugs for Adults and

Adolescents: a Public Health Approach:

Report of a WHO Working Group Meeting

National HIV/AIDS programmes are requesting additional operational

guidance on the composition of their antiretroviral (ARV) formularies

based on programme efficiencies and costs. As these drug formularies

are generally limited in developing countries, there is an increasing

and urgent need to establish principles and adequate criteria to

prioritize ARV options in this context. Prioritization of agents for

use in 2nd†" line regimens, comprising protease inhibitors,

nucleoside and nucleotide reverse transcriptase inhibitors are needed.

This report provides guidance on simplified second-line regimen

options that countries can choose and will also inform readers about

future revisions of the WHO ARV treatment guidelines.

Download file in English [pdf 593kb]

http://www.who.int/hiv/pub/meetingreports/second_line_art_report_2008.pdf